PIMA533121

Caspase 9 Recombinant Rabbit Monoclonal Antibody (2D5), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA533121-Each-of-1 In Stock ₹ 48,640.86

PIMA533121 - Each of 1

₹ 48,640.86

In Stock

Quantity

1

Base Price: ₹ 48,640.86

GST (18%): ₹ 8,755.355

Total Price: ₹ 57,396.215

Antigen

Caspase 9

Classification

Recombinant Monoclonal

Concentration

1.75 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

P55211

Gene Symbols

CASP9

Immunogen

A synthesized peptide derived from human CASP9

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Western Blot

Clone

2D5

Conjugate

Unconjugated

Gene

CASP9

Gene Alias

25 kDa caspase-9 dominant negative protein, AI115399, APAF3, APAF-3, apoptotic protease activating factor 3, apoptotic protease MCH-6, Apoptotic protease-activating factor 3, AW493809, cas9, CASP 9, CASP9, CASP-9, Casp9_v1, Casp-9-CTD, caspase 9, caspase 9, apoptosis-related cysteine peptidase, caspase 9, apoptosis-related cysteine protease, Caspase9, caspase-9, caspase-9 dominant negative form, Caspase-9 precursor, Caspase-9 subunit p10, Caspase-9 subunit p35, CASPASE-9c, caspase-9-carboxyl-terminal divergent, CTD, Ice-Lap6, ICE-like apoptotic protease 6, Mch6, OTTHUMP00000002324, PPP1R56, protein phosphatase 1, regulatory subunit 56, RNCASP9, RP11-265F14.3

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

842

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

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Description

  • Caspase 9 (ICE-like apoptotic protease 6, ICE LAP6, apoptotic protease Mch6, apoptotic protease activating factor 3, Apaf3) is a member of the peptidase family C14 that contains a CARD domain
  • Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates
  • Caspase 9 is active as a heterotetramer, is present in the cytosol and, upon activation, translocates to the mitochondria
  • Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6
  • Further, Caspase 9 is involved in the activation cascade of caspases responsible for apoptosis execution
  • Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3
  • Caspase 9 promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner, and proteolytically cleaves poly(ADP- ribose) polymerase (PARP)
  • Caspase 9 is expressed in variety of human tissues
  • An isoform of rat Caspase-9 has been identified in which the C terminus of full-length Caspase-9 is replaced with an alternative peptide sequence
  • Mutations in Caspase 9 affect brain development
  • In mice, insufficient Caspase 9 have resulted in abnormal cerebrum development and neuron development
  • In humans, dysfunctional Caspase 9 expression vary from tissue to tissue
  • Low levels of Caspase 9 may play a role in cancer development and neurodegenerative diseases such as Alzheimer’s Disease (AD).

Compare Similar Items

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Img

Thermo Scientific

PIMA533121

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Antigen:
Caspase 9

Classification:
Recombinant Monoclonal

Concentration:
1.75 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P55211

Gene Symbols:
CASP9

Immunogen:
A synthesized peptide derived from human CASP9

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
2D5

Conjugate:
Unconjugated

Gene:
CASP9

Gene Alias:
25 kDa caspase-9 dominant negative protein, AI115399, APAF3, APAF-3, apoptotic protease activating factor 3, apoptotic protease MCH-6, Apoptotic protease-activating factor 3, AW493809, cas9, CASP 9, CASP9, CASP-9, Casp9_v1, Casp-9-CTD, caspase 9, caspase 9, apoptosis-related cysteine peptidase, caspase 9, apoptosis-related cysteine protease, Caspase9, caspase-9, caspase-9 dominant negative form, Caspase-9 precursor, Caspase-9 subunit p10, Caspase-9 subunit p35, CASPASE-9c, caspase-9-carboxyl-terminal divergent, CTD, Ice-Lap6, ICE-like apoptotic protease 6, Mch6, OTTHUMP00000002324, PPP1R56, protein phosphatase 1, regulatory subunit 56, RNCASP9, RP11-265F14.3

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
842

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Img

Thermo Scientific

PIMA533122

--


Antigen:
CCR9

Classification:
Recombinant Monoclonal

Concentration:
1.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P51686, Q9WUT7

Gene Symbols:
Ccr9

Immunogen:
A synthesized peptide derived from human CCR9

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
4G2

Conjugate:
Unconjugated

Gene:
Ccr9

Gene Alias:
A130091K22Rik, C-C chemokine receptor type 9, C-C CKR-9, C-C motif chemokine receptor 9, CC-CKR-9, Ccr9, CCR-9, CDw199, CDw199 antigen, chemokine (C-C motif) receptor 9, chemokine C-C receptor 10, Cmkbr10, G protein-coupled receptor 28, GPR28, GPR-9-6, G-protein coupled receptor 28

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10803, 12769

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Img

Thermo Scientific

PIMA533123

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Antigen:
CD81

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P35762, P60033, Q62745

Gene Symbols:
CD81

Immunogen:
Synthesized CD81 (150-200aa)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
9F7

Conjugate:
Unconjugated

Gene:
CD81

Gene Alias:
26 kDa cell surface protein TAPA-1, CD 81 antigen, Cd81, CD81 antigen, CD81 antigen (target of antiproliferative antibody 1), CD81 molecule, CVID6, S5.7, Tapa1, Tapa-1, Target of the antiproliferative antibody 1, Tetraspanin28, tetraspanin-28, Tspan28, Tspan-28

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
12520, 25621, 975

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Img

Thermo Scientific

PIMA533125

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Antigen:
CD9

Classification:
Recombinant Monoclonal

Concentration:
0.25 mg/mL

Formulation:
PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P21926

Gene Symbols:
CD9

Immunogen:
Synthesized CD9

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunohistochemistry (Paraffin)

Clone:
3A2

Conjugate:
Unconjugated

Gene:
CD9

Gene Alias:
5H9, 5H9 antigen, antigen CD9, BA2, BA-2/p24 antigen, BTCC-1, CD9, CD9 antigen, CD9 antigen (p24), CD9 molecule, cell growth-inhibiting gene 2 protein, DRAP-27, GIG2, Leukocyte antigen MIC3, MIC3, motility related protein-1, Motility-related protein, MRP-1, p24, sCD 9, sCD9, soluble CD 9, soluble CD9, Tetraspanin29, Tetraspanin-29, transmembrane protein CD9, TSPAN29, Tspan-29

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
928

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid