PIMA532143

Phospho-SRC (Tyr419) Recombinant Rabbit Monoclonal Antibody (ST0800), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532143-Each-of-1 In Stock ₹ 45,646.26

PIMA532143 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

Phospho-SRC (Tyr419)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P05480, P12931, Q9WUD9

Gene Symbols

SRC

Immunogen

Synthetic phospho-peptide corresponding to residues surrounding Tyr419 of Human Src aa 401-450

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Western Blot

Clone

ST0800

Conjugate

Unconjugated

Gene

SRC

Gene Alias

ASV, AW259666, csrc, c-SRC, c-src protein, C terminus, EC 2.7.10.2, fc54g04, Neuronal proto-oncogene tyrosine-protein kinase Src, non-tyrosine protein kinase, ORF, OTTHUMP00000174476, OTTHUMP00000174477, OTTHUMP00000174478, p60-Src, p60-Src-1, PP60C-SCR, pp60c-src, pp60src, pp60v-src, protein-tyrosine kinase, proto-oncogene c-Src, protooncogene SRC, Rous sarcoma, Proto-oncogene tyrosine-protein kinase Src, Rous sarcoma oncogene, RP5-823N20.1, sb:cb864, SDR, src, src downstream region, src oncogene, SRC proto-oncogene, non-receptor tyrosine kinase, SRC proto-oncogene, non-receptor tyrosine kinase L homeolog, SRC proto-oncogene, non-receptor tyrosine kinase S homeolog, src.L, src.S, SRC1, src-1, src1-A, src-a, src-b, THC6, transforming protein, tyrosine kinase pp60c-src, tyrosine protein kinase c-src, tyrosine protein kinase pp60-c-src, tyrosine-protein kinase SRC-1, Unknown, v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog, v-src sarcoma (Schmidt-Ruppin A-2) viral oncogen

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

20779, 6714, 83805

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • SRC is a cytoplasmic tyrosine kinase and proto-oncogene involved in the regulation of embryonic development and cell growth
  • SRC is involved in the regulation of growth and differentiation of eukaryotic cells
  • SRC associates with the cytoplasmic region of various cell surface receptors to facilitate signal transduction, and is also involved in cytoskeletal organization, cell cycle regulation, and apoptosis
  • In humans, the gene encoding SRC is present on chromosome 20
  • Activity of SRC is regulated by two tyrosine residues (Tyr 416 and Tyr527), and phosphorylation of these two sites have opposing effects
  • Phosphorylation of Tyr416 in the activation loop of the kinase domain upregulates enzyme activity while the phosphorylation of Tyr527 decreases enzyme activity
  • Mutations in the SRC gene could be involved in the malignant progression of colon cancer
  • Two transcript variants encoding the same SRC protein have been found thus far.

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Img

Thermo Scientific

PIMA532143

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Antigen:
Phospho-SRC (Tyr419)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P05480, P12931, Q9WUD9

Gene Symbols:
SRC

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Tyr419 of Human Src aa 401-450

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Western Blot

Clone:
ST0800

Conjugate:
Unconjugated

Gene:
SRC

Gene Alias:
ASV, AW259666, csrc, c-SRC, c-src protein, C terminus, EC 2.7.10.2, fc54g04, Neuronal proto-oncogene tyrosine-protein kinase Src, non-tyrosine protein kinase, ORF, OTTHUMP00000174476, OTTHUMP00000174477, OTTHUMP00000174478, p60-Src, p60-Src-1, PP60C-SCR, pp60c-src, pp60src, pp60v-src, protein-tyrosine kinase, proto-oncogene c-Src, protooncogene SRC, Rous sarcoma, Proto-oncogene tyrosine-protein kinase Src, Rous sarcoma oncogene, RP5-823N20.1, sb:cb864, SDR, src, src downstream region, src oncogene, SRC proto-oncogene, non-receptor tyrosine kinase, SRC proto-oncogene, non-receptor tyrosine kinase L homeolog, SRC proto-oncogene, non-receptor tyrosine kinase S homeolog, src.L, src.S, SRC1, src-1, src1-A, src-a, src-b, THC6, transforming protein, tyrosine kinase pp60c-src, tyrosine protein kinase c-src, tyrosine protein kinase pp60-c-src, tyrosine-protein kinase SRC-1, Unknown, v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog, v-src sarcoma (Schmidt-Ruppin A-2) viral oncogen

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
20779, 6714, 83805

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532144

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Antigen:
Phospho-GATA3 (Ser308)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P23771

Gene Symbols:
GATA3

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Ser308 of Human GATA3 aa 281-330

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Clone:
ST44-09

Conjugate:
Unconjugated

Gene:
GATA3

Gene Alias:
EGK_19445, GATA binding factor-3, GATA binding protein 3, GATA binding protein-3, GATA3, Gata-3, GATA-binding factor 3, GATA-binding protein 3, HDR, HDRS, jal, MGC2346, MGC5199, MGC5445, Trans-acting T-cell-specific transcription factor GATA-3, Transacting T-cell-specific transcription factor GATA-3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2625

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532145

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Antigen:
Androgen Receptor

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P10275

Gene Symbols:
AR

Immunogen:
Synthetic peptide within Human Androgen receptor isform 3 aa 595-644

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
ST0453

Conjugate:
Unconjugated

Gene:
AR

Gene Alias:
AIS, Andr, androgen nuclear receptor variant 2, androgen receptor, androgen receptor (Testicular feminization), same as Tfm, androgen receptor splice variant 4b, Ar, AR8, AR-A, AW320017, DHTR, dihydrotestosterone receptor, HUMARA, HYSP1, KD, NR3C4, Nuclear receptor subfamily 3 group C member 4, RP11-383C12.1, SBMA, SMAX1, TFM, Variant AR45

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
367

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532146

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Antigen:
Aurora A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
O14965, P97477

Gene Symbols:
AURKA

Immunogen:
Synthetic peptide within Human Aurora A aa 1-50

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot, Western Blot

Clone:
ST46-07

Conjugate:
Unconjugated

Gene:
AURKA

Gene Alias:
Aik, Airk, AIRK1, Ark1, ARK-1, AU019385, AURA, AURAK, AURKA, Aurora 2, aurora A, Aurora A Kinase, aurora family kinase 1, Aurora kinase A, aurora/IP, aurora/IPL1-like kinase, aurora/IPL1-related kinase 1, AURORA2, Aurora-A, aurora-related kinase 1, AW539821, Ayk1, Breast tumor-amplified kinase, BTAK, EC 2.7.11.1, hARK1, IAK, IAK1, Ipl1- and aurora-related kinase 1, IPL1-related kinase, MGC34538, OTTHUMP00000031341, OTTHUMP00000166072, PPP1R47, protein phosphatase 1, regulatory subunit 47, ratAurA, RP5-1167H4.6, sereine threonine kinase, serine/threonine kinase 6, serine/threonine protein kinase 15, serine/threonine protein kinase 6, serine/threonine-protein kinase 15, Serine/threonine-protein kinase 6, serine/threonine-protein kinase 6, aurora kinase A, serine/threonine-protein kinase aurora-A, Serine/threonine-protein kinase Ayk1, STK15, STK6, STK7, Unknown (protein for MGC:134472)

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
20878, 6790

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid