PIMA532207

Phospho-TrkB (Tyr817) Recombinant Rabbit Monoclonal Antibody (SC0556), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532207-Each-of-1 In Stock ₹ 44,619.54

PIMA532207 - Each of 1

₹ 44,619.54

In Stock

Quantity

1

Base Price: ₹ 44,619.54

GST (18%): ₹ 8,031.517

Total Price: ₹ 52,651.057

Antigen

Phospho-TrkB (Tyr817)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P15209, Q16620, Q63604

Gene Symbols

Ntrk2

Immunogen

Synthetic phospho-peptide corresponding to residues surrounding Tyr817 of Human TrkB aa 789-822

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

SC0556

Conjugate

Unconjugated

Gene

Ntrk2

Gene Alias

AI848316, BDNF/NT-3 growth factors receptor, BDNF-tropomyosine receptor kinase B, C030027L06Rik, EC 2.7.10.1, GP145 TrkB, GP145TrkB, GP145-TrkB, GP145-TrkB/GP95-TrkB, GP95 TrkB, GP95-TrkB, hyperphagia, kinase TrkB, neural receptor protein-tyrosine kinase (trkB), neurotrophic receptor tyrosine kinase 2, neurotrophic tyrosine kinase receptor type 2, neurotrophic tyrosine kinase, receptor, type 2, neurotrophic tyrosine receptor kinase type 2, NTRK 2, Ntrk2, OTTHUMP00000021573, OTTHUMP00000021574, OTTHUMP00000021576, OTTHUMP00000021577, RATTRKB1, Tkrb, Trk B, TRKB, trk-B, trkB protein, trkB tyrosine kinase, TRKB1, Tropomyosin-related kinase B, tyrosine kinase receptor B

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

18212, 25054, 4915

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • NTRK2 (TRKB) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system
  • NTRK2 is the receptor for brain-derived neurotrophic factor (BDNF)
  • Together, NTRK2 and BDNF regulate both short-term synaptic functions and long-term potentiation of brain synapses
  • TrkB is involved in the development and maintenance of the nervous system
  • Moreover, Trk B is a tyrosine kinase gene highly related to Trk A
  • Trk B expression is confined to tissues within the central and peripheral nervous systems
  • The brain-derived neurotrophic factor (BDNF) and NT-3, but not NGF, can induce rapid phosphorylation on tyrosine of Trk B gp145, one of the receptors encoded by Trk B, although BDNF elicits a response at least two orders of magnitude greater than NT-3
  • TrkB is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway
  • Signaling through TrkB leads to cell differentiation
  • Mutations in the TrkB gene have been associated with obesity and mood disorders
  • Alternate transcriptional splice variants encoding different isoforms have been found for the TrkB gene.

Compare Similar Items

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Thermo Scientific

PIMA532207

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Antigen:
Phospho-TrkB (Tyr817)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P15209, Q16620, Q63604

Gene Symbols:
Ntrk2

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Tyr817 of Human TrkB aa 789-822

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SC0556

Conjugate:
Unconjugated

Gene:
Ntrk2

Gene Alias:
AI848316, BDNF/NT-3 growth factors receptor, BDNF-tropomyosine receptor kinase B, C030027L06Rik, EC 2.7.10.1, GP145 TrkB, GP145TrkB, GP145-TrkB, GP145-TrkB/GP95-TrkB, GP95 TrkB, GP95-TrkB, hyperphagia, kinase TrkB, neural receptor protein-tyrosine kinase (trkB), neurotrophic receptor tyrosine kinase 2, neurotrophic tyrosine kinase receptor type 2, neurotrophic tyrosine kinase, receptor, type 2, neurotrophic tyrosine receptor kinase type 2, NTRK 2, Ntrk2, OTTHUMP00000021573, OTTHUMP00000021574, OTTHUMP00000021576, OTTHUMP00000021577, RATTRKB1, Tkrb, Trk B, TRKB, trk-B, trkB protein, trkB tyrosine kinase, TRKB1, Tropomyosin-related kinase B, tyrosine kinase receptor B

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
18212, 25054, 4915

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532208

--


Antigen:
PIK3CB

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P42338

Gene Symbols:
PIK3CB

Immunogen:
Synthetic peptide within Human PIK3CB aa 5-52

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Western Blot

Clone:
SC0580

Conjugate:
Unconjugated

Gene:
PIK3CB

Gene Alias:
1110001J02Rik, AI447572, catalytic phosphatidylinositol 3-kinase beta, p110beta, phosphatidylinositol 3-kinase catalytic subunit beta isoform, phosphatidylinositol 3-kinase, catalytic subunit, beta isoform, phosphatidylinositol 3-kinase, catalytic, beta polypeptide, phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform, phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta, phosphoinositide-3-kinase, catalytic, beta polypeptide, PI3K, PI3Kbeta, PI3K-beta, pi3kcb, PI3-kinase p110 subunit beta, PI3-kinase subunit beta, PIK3C1, Pik3cb, PtdIns-3-kinase p110, ptdIns-3-kinase subunit beta, ptdIns-3-kinase subunit p110-beta

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5291

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532209

--


Antigen:
TPH1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P09810, P17532, P17752

Gene Symbols:
TPH1

Immunogen:
Synthetic peptide within Human TPH1 aa 372-419

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SC53-07

Conjugate:
Unconjugated

Gene:
TPH1

Gene Alias:
indoleacetic acid-5-hydroxylase, L-tryptophan hydroxylase, MGC119994, TPH, Tph1, TPH2, TPRH, TRPH, tryptophan 5-hydroxylase 1, Tryptophan 5-monooxygenase 1, tryptophan hydroxylase, tryptophan hydroxylase (tryptophan 5-monooxygenase), tryptophan hydroxylase 1, tryptophan hydroxylase 1 (tryptophan 5-monooxygenase)

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
21990, 24848, 7166

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532211

--


Antigen:
Phospho-EGFR (Tyr1173)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P00533

Gene Symbols:
EGFR

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Tyr1173 of Human EGFR .

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SC57-04

Conjugate:
Unconjugated

Gene:
EGFR

Gene Alias:
2.7.10.1, 9030024J15Rik, AI552599, avian erythroblastic leukemia viral (v-erbB) oncogene homolog, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10.1, egf receptor, Egfr, EGFR-related peptide, epidermal growth factor receptor, epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian), Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1), epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1), ERBB, ERBB1, ErbB-1, erb-b2 receptor tyrosine kinase 1, Errb1, Errp, HER1, kinase EGFR, mENA, NISBD2, Oncogene ERBB, PIG61, Proto-oncogene c-ErbB-1, receptor tyrosine-protein kinase erbB-1, Urogastrone, wa2, wa-2, Wa5, waved 2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1956

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid