PIMA532209
TPH1 Recombinant Rabbit Monoclonal Antibody (SC53-07), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532209-Each-of-1 | In Stock | ₹ 44,619.54 |
PIMA532209 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,619.54
GST (18%): ₹ 8,031.517
Total Price: ₹ 52,651.057
Antigen
TPH1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P09810, P17532, P17752
Gene Symbols
TPH1
Immunogen
Synthetic peptide within Human TPH1 aa 372-419
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
SC53-07
Conjugate
Unconjugated
Gene
TPH1
Gene Alias
indoleacetic acid-5-hydroxylase, L-tryptophan hydroxylase, MGC119994, TPH, Tph1, TPH2, TPRH, TRPH, tryptophan 5-hydroxylase 1, Tryptophan 5-monooxygenase 1, tryptophan hydroxylase, tryptophan hydroxylase (tryptophan 5-monooxygenase), tryptophan hydroxylase 1, tryptophan hydroxylase 1 (tryptophan 5-monooxygenase)
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
21990, 24848, 7166
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Tryptophan hydroxylase (TPH) catalyzes the 5-hydroxylation of tryptophan, which is the first step in the biosynthesis of indoleamines (serotonin and melatonin) (Martinez et al., 2001)
- In mammals, serotonin biosynthesis occurs predominantly in neurons which originate in the Raphe nuclei of the brain, and melatonin synthesis takes place within the pineal gland
- Although TPH catalyzes the same reaction within the Raphe nuclei and the pineal gland, TPH activity is rate-limiting for serotonin but not melatonin biosynthesis
- Serotonin functions mainly as a neurotransmitter, whereas melatonin is the principal hormone secreted by the pineal gland
- The activity of TPH is enhanced by phosphorylation by cAMP-dependent protein kinase (PKA) and Ca2+/calmodulin kinase II (CAM K II) (Jiang et al., 2000; Johansen et al., 1996)
- Both PKA and CAM K II phosphorylate Ser58 which lies within the regulatory domain of TPH (Kuhn et al., 1997).
Compare Similar Items
Show Difference
Antigen: TPH1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P09810, P17532, P17752
Gene Symbols: TPH1
Immunogen: Synthetic peptide within Human TPH1 aa 372-419
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SC53-07
Conjugate: Unconjugated
Gene: TPH1
Gene Alias: indoleacetic acid-5-hydroxylase, L-tryptophan hydroxylase, MGC119994, TPH, Tph1, TPH2, TPRH, TRPH, tryptophan 5-hydroxylase 1, Tryptophan 5-monooxygenase 1, tryptophan hydroxylase, tryptophan hydroxylase (tryptophan 5-monooxygenase), tryptophan hydroxylase 1, tryptophan hydroxylase 1 (tryptophan 5-monooxygenase)
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 21990, 24848, 7166
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
TPH1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P09810, P17532, P17752
Gene Symbols:
TPH1
Immunogen:
Synthetic peptide within Human TPH1 aa 372-419
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SC53-07
Conjugate:
Unconjugated
Gene:
TPH1
Gene Alias:
indoleacetic acid-5-hydroxylase, L-tryptophan hydroxylase, MGC119994, TPH, Tph1, TPH2, TPRH, TRPH, tryptophan 5-hydroxylase 1, Tryptophan 5-monooxygenase 1, tryptophan hydroxylase, tryptophan hydroxylase (tryptophan 5-monooxygenase), tryptophan hydroxylase 1, tryptophan hydroxylase 1 (tryptophan 5-monooxygenase)
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
21990, 24848, 7166
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Phospho-EGFR (Tyr1173)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P00533
Gene Symbols: EGFR
Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Tyr1173 of Human EGFR .
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SC57-04
Conjugate: Unconjugated
Gene: EGFR
Gene Alias: 2.7.10.1, 9030024J15Rik, AI552599, avian erythroblastic leukemia viral (v-erbB) oncogene homolog, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10.1, egf receptor, Egfr, EGFR-related peptide, epidermal growth factor receptor, epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian), Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1), epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1), ERBB, ERBB1, ErbB-1, erb-b2 receptor tyrosine kinase 1, Errb1, Errp, HER1, kinase EGFR, mENA, NISBD2, Oncogene ERBB, PIG61, Proto-oncogene c-ErbB-1, receptor tyrosine-protein kinase erbB-1, Urogastrone, wa2, wa-2, Wa5, waved 2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1956
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Phospho-EGFR (Tyr1173)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P00533
Gene Symbols:
EGFR
Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Tyr1173 of Human EGFR .
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SC57-04
Conjugate:
Unconjugated
Gene:
EGFR
Gene Alias:
2.7.10.1, 9030024J15Rik, AI552599, avian erythroblastic leukemia viral (v-erbB) oncogene homolog, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10.1, egf receptor, Egfr, EGFR-related peptide, epidermal growth factor receptor, epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian), Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1), epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1), ERBB, ERBB1, ErbB-1, erb-b2 receptor tyrosine kinase 1, Errb1, Errp, HER1, kinase EGFR, mENA, NISBD2, Oncogene ERBB, PIG61, Proto-oncogene c-ErbB-1, receptor tyrosine-protein kinase erbB-1, Urogastrone, wa2, wa-2, Wa5, waved 2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1956
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Ku80
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P13010
Gene Symbols: XRCC5
Immunogen: Synthetic peptide within Human Ku80 aa 693-732.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Immunohistochemistry, Western Blot
Clone: SC06-14
Conjugate: Unconjugated
Gene: XRCC5
Gene Alias: 86 kDa subunit of Ku antigen, AI314015, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 80 kDa subunit, CTC box-binding factor 85 kDa subunit, CTC85, CTCBF, DNA repair protein XRCC5, FLJ39089, G22p2, HGNC:12833, KARP1, KARP-1, Ku autoantigen, ku autoantigen protein p86 homolog, Ku autoantigen, 80kD), Ku autoantigen, 80kDa, Ku p80, Ku80, Ku-80, Ku86, Ku-86, Ku86 autoantigen related protein 1, KUB2, Kup80, Lupu, lupus, lupus Ku autoantigen protein p86, NFIV, nuclear factor IV, OTTHUMP00000164061, OTTHUMP00000206791, Thyroid-lupus autoantigen, TLAA, X-ray repair complementing defective repair in Chinese hamster cells 5, X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining), X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining, Ku autoantigen, 80kDa), X-ray repair cross complementation (double-strand-break rejoining, X-ray repair cross complementation (double-strand-break rejoining, Ku autoantigen, 80kD), X-ray repair cross complementing 5, X-ray repair cross-complementing protein 5, Xrcc5
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 7520
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Ku80
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P13010
Gene Symbols:
XRCC5
Immunogen:
Synthetic peptide within Human Ku80 aa 693-732.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Immunohistochemistry, Western Blot
Clone:
SC06-14
Conjugate:
Unconjugated
Gene:
XRCC5
Gene Alias:
86 kDa subunit of Ku antigen, AI314015, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 80 kDa subunit, CTC box-binding factor 85 kDa subunit, CTC85, CTCBF, DNA repair protein XRCC5, FLJ39089, G22p2, HGNC:12833, KARP1, KARP-1, Ku autoantigen, ku autoantigen protein p86 homolog, Ku autoantigen, 80kD), Ku autoantigen, 80kDa, Ku p80, Ku80, Ku-80, Ku86, Ku-86, Ku86 autoantigen related protein 1, KUB2, Kup80, Lupu, lupus, lupus Ku autoantigen protein p86, NFIV, nuclear factor IV, OTTHUMP00000164061, OTTHUMP00000206791, Thyroid-lupus autoantigen, TLAA, X-ray repair complementing defective repair in Chinese hamster cells 5, X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining), X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining, Ku autoantigen, 80kDa), X-ray repair cross complementation (double-strand-break rejoining, X-ray repair cross complementation (double-strand-break rejoining, Ku autoantigen, 80kD), X-ray repair cross complementing 5, X-ray repair cross-complementing protein 5, Xrcc5
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
7520
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Radixin
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P26043, P35241
Gene Symbols: Rdx
Immunogen: Synthetic peptide within Human Radixin aa 389-433
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SC06-22
Conjugate: Unconjugated
Gene: Rdx
Gene Alias: AA516625, DFNB24, ESP10, radixin, radixin isoform, Rdx
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 19684, 315655, 5962
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Radixin
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P26043, P35241
Gene Symbols:
Rdx
Immunogen:
Synthetic peptide within Human Radixin aa 389-433
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SC06-22
Conjugate:
Unconjugated
Gene:
Rdx
Gene Alias:
AA516625, DFNB24, ESP10, radixin, radixin isoform, Rdx
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
19684, 315655, 5962
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid