PIMA532216

Catenin alpha-1 Recombinant Rabbit Monoclonal Antibody (SC0619), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532216-Each-of-1 In Stock ₹ 45,646.26

PIMA532216 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

Catenin alpha-1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P26231, P35221

Gene Symbols

CTNNA1

Immunogen

Recombinant protein within Human alpha 1 Catenin aa 1-90

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

SC0619

Conjugate

Unconjugated

Gene

CTNNA1

Gene Alias

[a]E-catenin, 102 kDa cadherin-associated protein, 2010010M04Rik, AA517462, AI988031, alpha E catenin, alpha E-catenin, alpha(E)-catenin, alpha-E-catenin, cadherin associated protein, Cadherin-associated protein, CAP102, catenin (cadherin associated protein), alpha 1, catenin (cadherin-associated protein), alpha, catenin (cadherin-associated protein), alpha 1, catenin (cadherin-associated protein), alpha 1, 102kDa, catenin alpha 1, catenin alpha 1 S homeolog, catenin alpha-1, catenin, alpha 1, Catna1, cell-adhesion protein alphaE catenin, ctnna, ctnna1, ctnna1.S, MDPT2, Renal carcinoma antigen NY-REN-13, XELAEV_18020018mg

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

12385, 1495, 307505

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • Associates with the cytoplasmic domain of a variety of cadherins
  • The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties
  • Can associate with both E- and N-cadherins
  • Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions
  • In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherence junctions components
  • The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments
  • May play a crucial role in cell differentiation.

Compare Similar Items

Show Difference

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Thermo Scientific

PIMA532216

--


Antigen:
Catenin alpha-1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P26231, P35221

Gene Symbols:
CTNNA1

Immunogen:
Recombinant protein within Human alpha 1 Catenin aa 1-90

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SC0619

Conjugate:
Unconjugated

Gene:
CTNNA1

Gene Alias:
[a]E-catenin, 102 kDa cadherin-associated protein, 2010010M04Rik, AA517462, AI988031, alpha E catenin, alpha E-catenin, alpha(E)-catenin, alpha-E-catenin, cadherin associated protein, Cadherin-associated protein, CAP102, catenin (cadherin associated protein), alpha 1, catenin (cadherin-associated protein), alpha, catenin (cadherin-associated protein), alpha 1, catenin (cadherin-associated protein), alpha 1, 102kDa, catenin alpha 1, catenin alpha 1 S homeolog, catenin alpha-1, catenin, alpha 1, Catna1, cell-adhesion protein alphaE catenin, ctnna, ctnna1, ctnna1.S, MDPT2, Renal carcinoma antigen NY-REN-13, XELAEV_18020018mg

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12385, 1495, 307505

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532217

--


Antigen:
Melan-A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q16655

Gene Symbols:
MLANA

Immunogen:
Synthetic peptide within Human MelanA aa 2-43

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
SC56-02

Conjugate:
Unconjugated

Gene:
MLANA

Gene Alias:
A930034P04Rik, Antigen LB39-AA, antigen SK29-AA, MART1, MART-1, melan-A, melanoma antigen recognized by T-cells 1, melanoma associated antigen recognized by T-cells 1, MLANA, Protein Melan-A

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2315

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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Thermo Scientific

PIMA532219

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Antigen:
Asparagine Synthetase

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P08243, P49088, Q61024

Gene Symbols:
Asns

Immunogen:
Synthetic peptide within Human Asparagine synthetase aa 502-538

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SC67-07

Conjugate:
Unconjugated

Gene:
Asns

Gene Alias:
ASNS, ASNSD, asparagine synthetase, asparagine synthetase (glutamine-hydrolyzing), asparagine synthetase [glutamine-hydrolyzing], Cell cycle control protein TS11, Glutamine-dependent asparagine synthetase, TS11, TS11 cell cycle control protein

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
25612, 27053, 440

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532220

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Antigen:
CHK2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
O96017

Gene Symbols:
Chek2

Immunogen:
Recombinant protein within Human Chk2 aa 10-200

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SC604

Conjugate:
Unconjugated

Gene:
Chek2

Gene Alias:
CDS1, cds1 homolog, Checkpoint kinase 2, Checkpoint like protein CHK2, checkpoint-like protein CHK2, Chek2, Chk2, Chk2 (phospho T68), Chk2 (pThr68), CHK2 checkpoint homolog, CHK2 checkpoint homolog (S. pombe), Chk2 phospho, Chk2 phospho T68, del9, EC 2.7.11.1, hCds1, HuCds 1, HuCds1, kinase Chk2, LFS2, OTTHUMP00000199044, OTTHUMP00000199045, OTTHUMP00000199064, OTTHUMP00000199115, OTTHUMP00000199116, phospho Chk2 (T68), phospho Thr68 Chk2, PP1425, protein kinase Chk2, Rad53, Rad53 homolog, RP11-436C9.1, Serine/threonine protein kinase Chk2, serine/threonine-protein kinase Chk2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11200

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid