PIMA532234

GART Recombinant Rabbit Monoclonal Antibody (SC66-02), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532234-Each-of-1 In Stock ₹ 45,646.26

PIMA532234 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

GART

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P22102, Q64737

Gene Symbols

GART

Immunogen

Recombinant protein within Human GART aa 570-750

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

SC66-02

Conjugate

Unconjugated

Gene

GART

Gene Alias

5'-phosphoribosylglycinamide transformylase, AIR synthase, AIRS, Gaps, GAR transformylase, GARS, Gart, GARTF, glycinamide ribonucleotide formyltransferase, Glycinamide ribonucleotide synthetase, MGC47764, PAIS, PGFT, Phosphoribosylamine--glycine ligase, Phosphoribosyl-aminoimidazole synthetase, Phosphoribosylformylglycinamidine cyclo-ligase, Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide synthetase, PRGS, Trifunctional purine biosynthetic protein adenosine-3, Trifunctional purine biosynthetic protein adenosine-3-like protein

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

14450, 2618, 288259

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Related Products

Img

Thermo Scientific

PIPA5115269

--

Img

Thermo Scientific

PIMA532233

--

Img

Novus Biologicals

NB265621

--

Img

Novus Biologicals

NB268306

--

Img

Novus Biologicals

NB265526

--

Img

Novus Biologicals

NB266076

--

Img

Thermo Scientific

PIPA5119903

--

Img

Novus Biologicals

NBP169008

--

Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • MERTK is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including LGALS3, TUB, TULP1 or GAS6
  • Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis)
  • Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules
  • Following activation by ligand, interacts with GRB2 or PLCG2 and induces phosphorylation of MAPK1, MAPK2, FAK/PTK2 or RAC1
  • MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment
  • Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis
  • Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA532234

--


Antigen:
GART

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P22102, Q64737

Gene Symbols:
GART

Immunogen:
Recombinant protein within Human GART aa 570-750

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SC66-02

Conjugate:
Unconjugated

Gene:
GART

Gene Alias:
5'-phosphoribosylglycinamide transformylase, AIR synthase, AIRS, Gaps, GAR transformylase, GARS, Gart, GARTF, glycinamide ribonucleotide formyltransferase, Glycinamide ribonucleotide synthetase, MGC47764, PAIS, PGFT, Phosphoribosylamine--glycine ligase, Phosphoribosyl-aminoimidazole synthetase, Phosphoribosylformylglycinamidine cyclo-ligase, Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase, Phosphoribosylglycinamide synthetase, PRGS, Trifunctional purine biosynthetic protein adenosine-3, Trifunctional purine biosynthetic protein adenosine-3-like protein

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
14450, 2618, 288259

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532235

--


Antigen:
WAVE2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q8BH43, Q9Y6W5

Gene Symbols:
WASF2

Immunogen:
Synthetic peptide within Human WASF2 aa 440-485

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Clone:
SC66-05

Conjugate:
Unconjugated

Gene:
WASF2

Gene Alias:
AW742646, D4Ertd13e, dJ393P12.2, IMD2, protein WAVE-2, putative Wiskott-Aldrich syndrome protein family member 4, SCAR2, suppressor of cyclic-AMP receptor (WASP-family), verprolin homology domain-containing protein 2, WAS protein family member 2, WAS protein family, member 2, Wasf2, WASF4, WASP family protein member 2, WASP family protein member 4, WASP family Verprolin-homologous protein 2, WAVE2, Wiskott-Aldrich syndrome protein family member 2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10163, 242687, 313024

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532236

--


Antigen:
DAXX

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q9UER7

Gene Symbols:
DAXX

Immunogen:
Recombinant protein within Human Daxx aa 195-313

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot, Western Blot

Clone:
SC54-06

Conjugate:
Unconjugated

Gene:
DAXX

Gene Alias:
BING2, CENP-C binding protein, DADB-159G18.9, DAP6, Daxx, death domain associated protein, Death domain-associated protein 6, death-associated protein 6, death-domain associated protein, EAP1, ETS1-associated protein 1, Fas death domain-associated protein, Fas-binding protein, hDaxx, MGC126245, MGC126246, SMIM40, Unknown (protein for MGC:138055)

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1616

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532237

--


Antigen:
MEKK2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q61083, Q9Y2U5

Gene Symbols:
Map3k2

Immunogen:
Synthetic peptide within Human MEKK2 aa 1-47

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SC68-02

Conjugate:
Unconjugated

Gene:
Map3k2

Gene Alias:
2.7.11.25, 9630061B06Rik, AI585793, MAP/ERK kinase kinase 2, MAP3K2, MAPK/ERK kinase kinase 2, MAPKKK2, MEK kinase 2, MEKK 2, MEKK2, MEKK2B, mitogen activated protein kinase kinase kinase 2, mitogen-activated protein kinase kinase kinase 2, protein kinase MEKK2b

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10746, 171492, 26405

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid