PIMA532283

Phospho-SIRT1 (Ser47) Recombinant Rabbit Monoclonal Antibody (SN06-40), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532283-Each-of-1 In Stock ₹ 45,646.26

PIMA532283 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

Phospho-SIRT1 (Ser47)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

Q96EB6

Gene Symbols

SIRT1

Immunogen

Synthetic phospho-peptide corresponding to residues surrounding Ser47 of Human SIRT1 aa 30-79

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

SN06-40

Conjugate

Unconjugated

Gene

SIRT1

Gene Alias

75SirT1, AA673258, hSIR2, hSIRT1, mSIR2a, NAD-dependent deacetylase sirtuin-1, NAD-dependent protein deacetylase sirtuin-1, OTTHUMP00000198111, OTTHUMP00000198112, Regulatory protein SIR2 homolog 1, RP11-57G10.3, SIR2, Sir2a, SIR2alpha, SIR2L1, sir2-like 1, SIR2-like protein 1, SIRT 1, SIRT1, SIRT-1, SirtT1 75 kDa fragment, sirtuin 1, sirtuin 1 ((silent mating type information regulation 2, homolog) 1, sirtuin type 1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

23411

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • NAD-dependent protein deacetylase sirtuin-1 (SIRT1) links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, repsonse to DNA damage, metabolism, apoptosis, and autophagy
  • SIRT1 can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histone and DNA, leading to transcriptional repression
  • It is essential in skeletal muscle cell differentiation and in response to low nutrients mediates the inhibitory effect on skeletal myoblast differentiation which also involves 5'-AMP-activated protein kinase (AMPK) and nicotinamide phosphoribosyltransferase (NAMPT).

Compare Similar Items

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Img

Thermo Scientific

PIMA532283

--


Antigen:
Phospho-SIRT1 (Ser47)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q96EB6

Gene Symbols:
SIRT1

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Ser47 of Human SIRT1 aa 30-79

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SN06-40

Conjugate:
Unconjugated

Gene:
SIRT1

Gene Alias:
75SirT1, AA673258, hSIR2, hSIRT1, mSIR2a, NAD-dependent deacetylase sirtuin-1, NAD-dependent protein deacetylase sirtuin-1, OTTHUMP00000198111, OTTHUMP00000198112, Regulatory protein SIR2 homolog 1, RP11-57G10.3, SIR2, Sir2a, SIR2alpha, SIR2L1, sir2-like 1, SIR2-like protein 1, SIRT 1, SIRT1, SIRT-1, SirtT1 75 kDa fragment, sirtuin 1, sirtuin 1 ((silent mating type information regulation 2, homolog) 1, sirtuin type 1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
23411

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532284

--


Antigen:
RAD18

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q9NS91, Q9QXK2

Gene Symbols:
Rad18

Immunogen:
Synthetic peptide within Human RAD18 aa 50-99

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SN66-01

Conjugate:
Unconjugated

Gene:
Rad18

Gene Alias:
2810024C04Rik, E3 ubiquitin-protein ligase RAD18, hHR18, hRAD18, mRAD18Sc, postreplication repair protein hRAD18p, postreplication repair protein RAD18, post-replication repair protein RAD18SC, Rad18, RAD18 E3 ubiquitin protein ligase, RAD18 homolog, RAD18 homolog (S. cerevisiae), RAD18, E3 ubiquitin protein ligase, RAD18, S. cerevisiae, homolog, Rad18sc, RING finger protein 73, RING-type E3 ubiquitin transferase RAD18, RNF73

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
362412, 56852, 58186

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532285

--


Antigen:
MMP11

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P24347, Q02853, Q499S5

Gene Symbols:
Mmp11

Immunogen:
Synthetic peptide within Human MMP11 aa 439-488

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SN74-08

Conjugate:
Unconjugated

Gene:
Mmp11

Gene Alias:
matrix metallo protease, matrix metallopeptidase 11, matrix metallopeptidase 11 (stromelysin 3), Matrix metalloproteinase 11 (stromelysin 3), matrix metalloproteinase-11, MMP, MMP11, MMP-11, MMPs, SL-3, ST3, Stmy3, stromelysin III, stromelysin-3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
17385, 25481, 4320

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532286

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Antigen:
TACC3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q9JJ11, Q9Y6A5

Gene Symbols:
TACC3

Immunogen:
Synthetic peptide within Human TACC3 aa 35-84

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SN73-05

Conjugate:
Unconjugated

Gene:
TACC3

Gene Alias:
Aint, Arnt interacting protein, ARNT-interacting protein, C86661, ERIC1, ERIC-1, Tacc3, transforming acidic coiled coil 3, transforming acidic coiled-coil containing protein 3, transforming acidic coiled-coil-containing protein 3, transforming, acidic coiled-coil containing protein 3

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10460, 21335, 360962

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid