PIMA532613

NEFM Recombinant Rabbit Monoclonal Antibody (JM11-20), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532613-Each-of-1 In Stock ₹ 56,041.80

PIMA532613 - Each of 1

₹ 56,041.80

In Stock

Quantity

1

Base Price: ₹ 56,041.80

GST (18%): ₹ 10,087.524

Total Price: ₹ 66,129.324

Antigen

NEFM

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P07197, P08553, P12839

Gene Symbols

NEFM

Immunogen

Synthetic peptide within Human NEFM aa 651-692

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

JM11-20

Conjugate

Unconjugated

Gene

NEFM

Gene Alias

160 kDa neurofilament protein, major neuronal intermediate filament subunit, medium neurofilament subunit, middle molecular weight neurofilament protein NF-M(2), Nef3, Nefm, nef-m, nefm.S, nefm-a, nefm-b, Neurofilament 3, neurofilament 3 (150kDa medium), neurofilament 3, medium, neurofilament M subunit, neurofilament medium, neurofilament medium polypeptide, neurofilament medium S homeolog, neurofilament medium tail domain, neurofilament protein M, Neurofilament protein, middle polypeptide, neurofilament triplet M protein, neurofilament, medium polypeptide, neurofilament, medium polypeptide 150kDa, neurofilament, medium polypeptide S homeolog, neurofilament-3 (150 kD medium), neurofilament-M, neurofilament-M subunit, neuronal intermediate filament, NF160, NF165, NFM, NF-M, NF-M c-terminus, NF-M protein, NMC, XELAEV_18020229mg

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

18040, 24588, 4741

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • Neurofilaments (NFs) are a type of intermediate filament (IF) expressed almost exclusively in neuronal cells, and in those cells most prominently in large axons
  • NFs, in most vertebrates, are composed of three different polypeptide chains with different molecular weights - neurofilament medium protein (NF-M), high (NF-H) and light protein (NF-L), which share sequence and structural similarity in a coiled-coil core domain, but differ in the length and sequence of their N-termini and more dramatically of their C-termini which in the case of NF-M and NF-H form the flexible extensions that link NFs to each other and to other elements in the cytoplasm
  • NF-M protein tail-mediated interactions of neurofilaments are critical for size and cytoskeletal architecture of axons, and are mediated, in part, by the highly phosphorylated tail domain of this protein
  • NF-M phosphorylation and O-GlcNAcylation are regulated reciprocally and affect its translocation and filament formation and function
  • Antibodies to the various neurofilament subunits are very useful cell type markers since the proteins are among the most abundant of the nervous system, are expressed only in neurons and are biochemically very stable.

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Img

Thermo Scientific

PIMA532613

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Antigen:
NEFM

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P07197, P08553, P12839

Gene Symbols:
NEFM

Immunogen:
Synthetic peptide within Human NEFM aa 651-692

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JM11-20

Conjugate:
Unconjugated

Gene:
NEFM

Gene Alias:
160 kDa neurofilament protein, major neuronal intermediate filament subunit, medium neurofilament subunit, middle molecular weight neurofilament protein NF-M(2), Nef3, Nefm, nef-m, nefm.S, nefm-a, nefm-b, Neurofilament 3, neurofilament 3 (150kDa medium), neurofilament 3, medium, neurofilament M subunit, neurofilament medium, neurofilament medium polypeptide, neurofilament medium S homeolog, neurofilament medium tail domain, neurofilament protein M, Neurofilament protein, middle polypeptide, neurofilament triplet M protein, neurofilament, medium polypeptide, neurofilament, medium polypeptide 150kDa, neurofilament, medium polypeptide S homeolog, neurofilament-3 (150 kD medium), neurofilament-M, neurofilament-M subunit, neuronal intermediate filament, NF160, NF165, NFM, NF-M, NF-M c-terminus, NF-M protein, NMC, XELAEV_18020229mg

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
18040, 24588, 4741

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532615

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Antigen:
TIA-1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P31483, P52912

Gene Symbols:
TIA1

Immunogen:
Synthetic peptide within Human TIA1 aa 353-386

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Immunoprecipitation, Western Blot, Western Blot

Clone:
JM42-11

Conjugate:
Unconjugated

Gene:
TIA1

Gene Alias:
2310050N03Rik, AI256674, cytotoxic granule-associated RNA binding protein 1, cytotoxic granule-associated RNA-binding protein 1, mTIA-1, Nucleolysin TIA-1, nucleolysin TIA-1 isoform p40, p40 TIA 1, p40-TIA-1, p40-TIA-1 (containing p15-TIA-1), RNA-binding protein TIA-1, T-cell-restricted intracellular antigen-1, Tia, TIA 1, TIA1, TIA-1, TIA1 cytotoxic granule-associated RNA binding protein, TIA1 protein, TIAL1, TIAR, WDM

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
21841, 7072

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532618

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Antigen:
TNFR2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P20333, P25119, Q80WY6

Gene Symbols:
Tnfrsf1b

Immunogen:
Synthetic peptide within Human TNF Receptor II aa 426-461

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot, Western Blot

Clone:
JM113-01

Conjugate:
Unconjugated

Gene:
Tnfrsf1b

Gene Alias:
CD120b, Etanercept, p75, p75 TNF receptor, p75 TNFR, p75TNFR, p80 TNF-alpha receptor, sCD120b, soluble CD120b, soluble TNFR1B variant 1, soluble TNFR2, sTNF R2, sTNFR 2, sTNFR2, TBP-2, TBPII, TNF receptor beta chain, TNF receptor superfamily member 1B, TNF-alphaR2, TNFalpha-R2, TNFBR, TNFR, TNFR II, Tnfr-1, TNFR1B, TNFR2, TNF-R2, Tnfr-2, TNF-R75, TNFR80, TNFRII, TNF-RII, TNF-R-II, TNFR-II, TNFRSF1B, tumor necrosis factor beta receptor, tumor necrosis factor binding protein 2, Tumor necrosis factor receptor, tumor necrosis factor receptor 2, Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor superfamily member 1b, membrane form, tumor necrosis factor receptor superfamily, member 1B, tumor necrosis factor receptor type II, Tumor necrosis factor-binding protein 2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
156767, 21938, 7133

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532619

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Antigen:
CD154 (CD40 Ligand)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P27548, P29965

Gene Symbols:
CD40LG

Immunogen:
Synthetic peptide within Human CD40L aa 103-150

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JM11-34

Conjugate:
Unconjugated

Gene:
CD40LG

Gene Alias:
CD154, CD40 antigen ligand, CD40 ligand, CD40 ligand CD154, CD40 ligand, membrane form, CD40 ligand, soluble form, CD40L, CD40-L, Cd40lg, gp39, hCD40L, H-CD-40-L, HIGM1, IGM, IMD3, Ly62, Ly-62, M-CD-40-L, RP23-153G22.3, T-B cell-activating molecule, T-BAM, T-cell antigen Gp39, TNF-related activation protein, TNFSF5, TRAP, tumor necrosis factor (ligand) superfamily member 5, tumor necrosis factor (ligand) superfamily, member 5, tumor necrosis factor ligand superfamily member 5

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
21947, 959

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid