PIMA532793

CD11b Recombinant Rabbit Monoclonal Antibody (JU93-81), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532793-Each-of-1 In Stock ₹ 45,817.38

PIMA532793 - Each of 1

₹ 45,817.38

In Stock

Quantity

1

Base Price: ₹ 45,817.38

GST (18%): ₹ 8,247.128

Total Price: ₹ 54,064.508

Antigen

CD11b

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P11215

Gene Symbols

ITGAM

Immunogen

Synthetic peptide within Human CD11b 1103-1152

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Western Blot

Clone

JU93-81

Conjugate

Unconjugated

Gene

ITGAM

Gene Alias

antigen CD11b (p170), antigen CD11b (p170), macrophage antigen alpha polypeptide, CD11 antigen-like family member B, CD11b, CD11B (p170), CD11b/CD18, cell surface glycoprotein MAC-1 alpha subunit, cell surface glycoprotein MAC-1 subunit alpha, complement component 3 receptor 3 subunit, complement component receptor 3 alpha-a, complement receptor type 3, CR3, CR-3 alpha chain, CR3A, F730045J24Rik, integrin alpha M, integrin alpha-M, integrin subunit alpha M, integrin, alpha M, integrin, alpha M (complement component 3 receptor 3 subunit), ITGAM, Leukocyte adhesion receptor MO1, leukocyte integrin alpha-M chain, LOC100351865, Ly-40, MAC1, Mac-1, Mac-1 alpha, Mac-1 alpha (Mac1A), MAC-1 alpha subunit, MAC1A, Mac-1a, macrophage antigen alpha, macrophage antigen alpha polypeptide, MGC117044, MO1A, Neutrophil adherence receptor, neutrophil adherence receptor alpha-M subunit, SLEB6, unnamed protein product

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

3684

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Related Products

Img

Thermo Scientific

PIMA532189

--

Img

Thermo Scientific

PIMA532306

--

Img

Thermo Scientific

PIMA532677

--

Img

Thermo Scientific

PIMA533356

--

Img

Thermo Scientific

PIMA532195

--

Img

Thermo Scientific

PIMA532050

--

Img

Thermo Scientific

PIMA532278

--

Img

Thermo Scientific

PIMA532433

--

Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • CD11b (integrin alpha-M, ITGAM, integrin alpha-X, ITGAX) is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18)
  • The CD11b/CD18 heterodimeric complex is also known as integrin alpha-M beta-2, Mac-1, and CR3 (complement receptor 3)
  • CD11b is expressed on the surface of monocytes/macrophages, granulocytes, activated lymphocytes, a subset of NK cells, a subset of dendritic cells, and microglia in the brain
  • CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions
  • CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue
  • The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages
  • Further, peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages
  • Diseases associated with CD11b dysfunction include systemic lupus erythematosus 6 and ITGAM-related susceptibility to systemic lupus erythematosus.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA532793

--


Antigen:
CD11b

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P11215

Gene Symbols:
ITGAM

Immunogen:
Synthetic peptide within Human CD11b 1103-1152

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Western Blot

Clone:
JU93-81

Conjugate:
Unconjugated

Gene:
ITGAM

Gene Alias:
antigen CD11b (p170), antigen CD11b (p170), macrophage antigen alpha polypeptide, CD11 antigen-like family member B, CD11b, CD11B (p170), CD11b/CD18, cell surface glycoprotein MAC-1 alpha subunit, cell surface glycoprotein MAC-1 subunit alpha, complement component 3 receptor 3 subunit, complement component receptor 3 alpha-a, complement receptor type 3, CR3, CR-3 alpha chain, CR3A, F730045J24Rik, integrin alpha M, integrin alpha-M, integrin subunit alpha M, integrin, alpha M, integrin, alpha M (complement component 3 receptor 3 subunit), ITGAM, Leukocyte adhesion receptor MO1, leukocyte integrin alpha-M chain, LOC100351865, Ly-40, MAC1, Mac-1, Mac-1 alpha, Mac-1 alpha (Mac1A), MAC-1 alpha subunit, MAC1A, Mac-1a, macrophage antigen alpha, macrophage antigen alpha polypeptide, MGC117044, MO1A, Neutrophil adherence receptor, neutrophil adherence receptor alpha-M subunit, SLEB6, unnamed protein product

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3684

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532797

--


Antigen:
HPRT1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P00492, P00493, P27605

Gene Symbols:
Hprt, HPRT1

Immunogen:
Synthetic peptide within Human HPRT aa 169-218

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat, Zebrafish

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
JU03-26

Conjugate:
Unconjugated

Gene:
HPRT1

Gene Alias:
C81579, HGPRT, HGPRTase, HPGRT, Hprt, HPRT 1, HPRT B, Hprt1, hprt1 protein, hypoxanthine guanine phosphoribosyl transferase, hypoxanthine guanine phosphoribosyl transferase 1, hypoxanthine phosphoribosyl transferase, hypoxanthine phosphoribosyltransferase 1, hypoxanthine-guanine phosphoribosyltransferase, hypoxanthine-guanine phosphoribosyltransferase 1, id:ibd1344, id:ibd5108, testicular tissue protein Li 89, wu:fc10g09, zgc:56221, zgc:86608

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
15452, 24465, 3251, 406259

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532798

--


Antigen:
IFITM3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q01628

Gene Symbols:
IFITM3

Immunogen:
Synthetic peptide within Human Fragilis aa 1-50

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JU73-02

Conjugate:
Unconjugated

Gene:
IFITM3

Gene Alias:
1110004C05Rik, 1-8U, Cd225, Cdw217, Dispanin subfamily A member 2b, DSPA2b, Fgls, Fragilis, Fragilis 3, Fragilis protein, Ifitm3, ifitm-like protein 1, interferon induced transmembrane protein 3, interferon-induced transmembrane protein 3, interferon-inducible protein 15, Interferon-inducible protein 1-8U, interferon-inducible protein variant 10, IP15, mil-1, Mouse ifitm-like protein 1, rat8

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10410

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532799

--


Antigen:
Hemopexin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P02790

Gene Symbols:
Hpx

Immunogen:
Synthetic peptide within Human Hemopexin aa 413-462

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot, Western Blot

Clone:
JU83-33

Conjugate:
Unconjugated

Gene:
Hpx

Gene Alias:
Beta-1B-glycoprotein, hemopexin, HPX, Hpxn, hx, hyaluronidase

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3263

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid