PIMA532677

ITGA4 Recombinant Rabbit Monoclonal Antibody (JA09-36), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532677-Each-of-1 In Stock ₹ 45,646.26

PIMA532677 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

ITGA4

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P13612, Q00651

Gene Symbols

ITGA4

Immunogen

Synthetic peptide within Human Integrin alpha 4 aa 983-1032

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunohistochemistry, Western Blot

Clone

JA09-36

Conjugate

Unconjugated

Gene

ITGA4

Gene Alias

269C wild type, alpha 4 subunit of VLA-4 receptor, antigen CD49D, alpha-4 subunit of VLA-4 receptor, CD49 antigen-like family member D, CD49d, IA4, integrin alpha 4, integrin alpha-4, integrin alpha4B, Integrin alpha-IV, integrin subunit alpha 4, integrin, alpha 4, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), Itga4, Itga4B, ITGA-IV, LPAM subunit alpha, lymphocyte Peyer patch adhesion molecules subunit alpha, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 receptor, alpha 4 subunit, VLA-4 subunit alpha

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

16401, 311144, 3676

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • The integrin alpha 4 (also known as CD49d and ITGA4) belongs to the integrin alpha chain family of proteins
  • Integrins are heterodimeric integral membrane proteins composed of an alpha and beta chains
  • Alpha4 chain associates with either beta1 or beta7 chain
  • It has been demonstrated that the putative ligand-binding sites of both integrin alpha4beta1 and alpha4beta7 is located on the alpha4 chain
  • These ligands included Madcam, VCAM, and fibronectin
  • Madcam is known as the principal ligand for integrin alpha4beta7
  • Recently it was also demonstrated that HIV-1 envelope can mimic Madcam by binding to and signaling though integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.

Compare Similar Items

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Img

Thermo Scientific

PIMA532677

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Antigen:
ITGA4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P13612, Q00651

Gene Symbols:
ITGA4

Immunogen:
Synthetic peptide within Human Integrin alpha 4 aa 983-1032

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunohistochemistry, Western Blot

Clone:
JA09-36

Conjugate:
Unconjugated

Gene:
ITGA4

Gene Alias:
269C wild type, alpha 4 subunit of VLA-4 receptor, antigen CD49D, alpha-4 subunit of VLA-4 receptor, CD49 antigen-like family member D, CD49d, IA4, integrin alpha 4, integrin alpha-4, integrin alpha4B, Integrin alpha-IV, integrin subunit alpha 4, integrin, alpha 4, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), Itga4, Itga4B, ITGA-IV, LPAM subunit alpha, lymphocyte Peyer patch adhesion molecules subunit alpha, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 receptor, alpha 4 subunit, VLA-4 subunit alpha

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
16401, 311144, 3676

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532679

--


Antigen:
NOXA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q13794

Gene Symbols:
PMAIP1

Immunogen:
Synthetic peptide within Human Noxa aa 5-54

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunohistochemistry, Western Blot

Clone:
JA30-03

Conjugate:
Unconjugated

Gene:
PMAIP1

Gene Alias:
adult T cell leukemia-derived PMA-responsive, APR, Immediate-early-response protein APR, Noxa, Phorbol-12-myristate-13-acetate-induced protein 1, PMA-ind, PMA-induced protein 1, Pmaip1, Protein Noxa

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5366

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532683

--


Antigen:
Profilin 1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P07737, P62962, P62963

Gene Symbols:
Pfn1

Immunogen:
Synthetic peptide within Human Profilin 1 aa 91-140

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JA30-13

Conjugate:
Unconjugated

Gene:
Pfn1

Gene Alias:
actin binding protein, ALS18, Epididymis tissue protein Li 184a, Pfn, Pfn1, profilin 1, profilin I, Profilin-1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
18643, 5216, 64303

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532684

--


Antigen:
CD163

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q86VB7

Gene Symbols:
CD163

Immunogen:
Recombinant protein within Human CD163 aa 1012-1149

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunohistochemistry, Western Blot

Clone:
JA51-30

Conjugate:
Unconjugated

Gene:
CD163

Gene Alias:
CD163, CD163 antigen, CD163 molecule, CD163v2, CD163v3, Hemoglobin scavenger receptor, M130, macrophage-associated antigen, MM130, putative CD163 antigen, SCARI1, Scavenger receptor cysteine-rich type 1 protein M130, sCD163, Soluble CD163, Soluble sCD163

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9332

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid