PIMA532679
NOXA Recombinant Rabbit Monoclonal Antibody (JA30-03), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532679-Each-of-1 | In Stock | ₹ 45,817.38 |
PIMA532679 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,817.38
GST (18%): ₹ 8,247.128
Total Price: ₹ 54,064.508
Antigen
NOXA
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
Q13794
Gene Symbols
PMAIP1
Immunogen
Synthetic peptide within Human Noxa aa 5-54
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunohistochemistry, Western Blot
Clone
JA30-03
Conjugate
Unconjugated
Gene
PMAIP1
Gene Alias
adult T cell leukemia-derived PMA-responsive, APR, Immediate-early-response protein APR, Noxa, Phorbol-12-myristate-13-acetate-induced protein 1, PMA-ind, PMA-induced protein 1, Pmaip1, Protein Noxa
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
5366
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Apoptosis is related to many diseases and development
- The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes including p53R2, p53AIP1, and PUMA
- A new p53 target gene, Noxa, was recently identified, which encodes a protein belonging to the subfamily of BH3-only proapoptic proteins
- Noxa and PUMA are both transcriptional targets of p53 and BH3-only proteins
- X-ray irradiation increased p53-dependent Noxa mRNA and protein levels
- Noxa, when ectopically expressed, interacted with anti-apoptotic Bcl-2 family members, resulting in the activation of caspase-9
- Noxa, like PUMA, localized to mitochondria and induces apoptosis in response to p53
- Noxa and PUMA may represent direct mediators of p53-induced apoptosis
- Increased levels of p53 and its target gene Noxa was found in the impaired tumor development.
Compare Similar Items
Show Difference
Antigen: NOXA
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: Q13794
Gene Symbols: PMAIP1
Immunogen: Synthetic peptide within Human Noxa aa 5-54
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunohistochemistry, Western Blot
Clone: JA30-03
Conjugate: Unconjugated
Gene: PMAIP1
Gene Alias: adult T cell leukemia-derived PMA-responsive, APR, Immediate-early-response protein APR, Noxa, Phorbol-12-myristate-13-acetate-induced protein 1, PMA-ind, PMA-induced protein 1, Pmaip1, Protein Noxa
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5366
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
NOXA
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
Q13794
Gene Symbols:
PMAIP1
Immunogen:
Synthetic peptide within Human Noxa aa 5-54
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunohistochemistry, Western Blot
Clone:
JA30-03
Conjugate:
Unconjugated
Gene:
PMAIP1
Gene Alias:
adult T cell leukemia-derived PMA-responsive, APR, Immediate-early-response protein APR, Noxa, Phorbol-12-myristate-13-acetate-induced protein 1, PMA-ind, PMA-induced protein 1, Pmaip1, Protein Noxa
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5366
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Profilin 1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P07737, P62962, P62963
Gene Symbols: Pfn1
Immunogen: Synthetic peptide within Human Profilin 1 aa 91-140
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: JA30-13
Conjugate: Unconjugated
Gene: Pfn1
Gene Alias: actin binding protein, ALS18, Epididymis tissue protein Li 184a, Pfn, Pfn1, profilin 1, profilin I, Profilin-1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 18643, 5216, 64303
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Profilin 1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P07737, P62962, P62963
Gene Symbols:
Pfn1
Immunogen:
Synthetic peptide within Human Profilin 1 aa 91-140
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
JA30-13
Conjugate:
Unconjugated
Gene:
Pfn1
Gene Alias:
actin binding protein, ALS18, Epididymis tissue protein Li 184a, Pfn, Pfn1, profilin 1, profilin I, Profilin-1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
18643, 5216, 64303
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: CD163
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: Q86VB7
Gene Symbols: CD163
Immunogen: Recombinant protein within Human CD163 aa 1012-1149
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunohistochemistry, Western Blot
Clone: JA51-30
Conjugate: Unconjugated
Gene: CD163
Gene Alias: CD163, CD163 antigen, CD163 molecule, CD163v2, CD163v3, Hemoglobin scavenger receptor, M130, macrophage-associated antigen, MM130, putative CD163 antigen, SCARI1, Scavenger receptor cysteine-rich type 1 protein M130, sCD163, Soluble CD163, Soluble sCD163
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 9332
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
CD163
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
Q86VB7
Gene Symbols:
CD163
Immunogen:
Recombinant protein within Human CD163 aa 1012-1149
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunohistochemistry, Western Blot
Clone:
JA51-30
Conjugate:
Unconjugated
Gene:
CD163
Gene Alias:
CD163, CD163 antigen, CD163 molecule, CD163v2, CD163v3, Hemoglobin scavenger receptor, M130, macrophage-associated antigen, MM130, putative CD163 antigen, SCARI1, Scavenger receptor cysteine-rich type 1 protein M130, sCD163, Soluble CD163, Soluble sCD163
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
9332
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: NFATC1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: O95644
Gene Symbols: NFATC1
Immunogen: Synthetic peptide within Human NFAT2 aa 894-943
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: JA81-03
Conjugate: Unconjugated
Gene: NFATC1
Gene Alias: 2210017P03Rik, AI449492, AV076380, MGC138448, NFAT tra, NFAT trans, NFAT transcription complex cytosolic component, NFAT2, NFATc, NF-ATC, NFATC1, NF-ATc1, NF-ATc1.2, Nfatcb, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1, nuclear factor of activated T-cells 1, nuclear factor of activated T-cells 'c', nuclear factor of activated T-cells, cytoplasmic 1, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1, transcription factor NF-ATc
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4772
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
NFATC1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
O95644
Gene Symbols:
NFATC1
Immunogen:
Synthetic peptide within Human NFAT2 aa 894-943
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
JA81-03
Conjugate:
Unconjugated
Gene:
NFATC1
Gene Alias:
2210017P03Rik, AI449492, AV076380, MGC138448, NFAT tra, NFAT trans, NFAT transcription complex cytosolic component, NFAT2, NFATc, NF-ATC, NFATC1, NF-ATc1, NF-ATc1.2, Nfatcb, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1, nuclear factor of activated T-cells 1, nuclear factor of activated T-cells 'c', nuclear factor of activated T-cells, cytoplasmic 1, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1, transcription factor NF-ATc
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4772
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid