PIMA532684
CD163 Recombinant Rabbit Monoclonal Antibody (JA51-30), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532684-Each-of-1 | In Stock | ₹ 44,619.54 |
PIMA532684 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,619.54
GST (18%): ₹ 8,031.517
Total Price: ₹ 52,651.057
Antigen
CD163
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
Q86VB7
Gene Symbols
CD163
Immunogen
Recombinant protein within Human CD163 aa 1012-1149
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunohistochemistry, Western Blot
Clone
JA51-30
Conjugate
Unconjugated
Gene
CD163
Gene Alias
CD163, CD163 antigen, CD163 molecule, CD163v2, CD163v3, Hemoglobin scavenger receptor, M130, macrophage-associated antigen, MM130, putative CD163 antigen, SCARI1, Scavenger receptor cysteine-rich type 1 protein M130, sCD163, Soluble CD163, Soluble sCD163
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
9332
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- CD163 (M130 antigen, Ber-Mac3, Ki-M8, SM4) is a 130 kDa membrane glycoprotein, a member of the scavenger receptor cysteine-rich superfamily, and a receptor for the hemoglobin-haptoglobin complex
- CD163 protects tissues from free hemoglobin-mediated oxidative damage, and may play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme
- CD163 is expressed exclusively on the cell surface of human monocytes and macrophages that evolve predominantly in the late phase of inflammation
- Specifically, CD163 is present on all circulating monocytes and most tissue macrophages except those found in the mantle zone and germinal centers of lymphoid follicles, interdigitating reticulum cells and Langerhan's cells
- CD163 is present on all CD14 positive monocytes, most CD64 positive monocytes, and shows higher expression on CD16 positive monocytes
- CD163 is upregulated on mononuclear phagocytes by IL-10, IL-6 and dexamethasone
- Lipopolysaccharide (LPS) and phorbol myristate acetate (PMA) both induce shedding of CD163 from the cell surface into plasma or cell supernatant
- CD163 binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner, and exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP1S phenotype
- Further, CD163 also induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1.
Compare Similar Items
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Antigen: CD163
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: Q86VB7
Gene Symbols: CD163
Immunogen: Recombinant protein within Human CD163 aa 1012-1149
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunohistochemistry, Western Blot
Clone: JA51-30
Conjugate: Unconjugated
Gene: CD163
Gene Alias: CD163, CD163 antigen, CD163 molecule, CD163v2, CD163v3, Hemoglobin scavenger receptor, M130, macrophage-associated antigen, MM130, putative CD163 antigen, SCARI1, Scavenger receptor cysteine-rich type 1 protein M130, sCD163, Soluble CD163, Soluble sCD163
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 9332
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
CD163
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
Q86VB7
Gene Symbols:
CD163
Immunogen:
Recombinant protein within Human CD163 aa 1012-1149
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunohistochemistry, Western Blot
Clone:
JA51-30
Conjugate:
Unconjugated
Gene:
CD163
Gene Alias:
CD163, CD163 antigen, CD163 molecule, CD163v2, CD163v3, Hemoglobin scavenger receptor, M130, macrophage-associated antigen, MM130, putative CD163 antigen, SCARI1, Scavenger receptor cysteine-rich type 1 protein M130, sCD163, Soluble CD163, Soluble sCD163
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
9332
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: NFATC1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: O95644
Gene Symbols: NFATC1
Immunogen: Synthetic peptide within Human NFAT2 aa 894-943
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: JA81-03
Conjugate: Unconjugated
Gene: NFATC1
Gene Alias: 2210017P03Rik, AI449492, AV076380, MGC138448, NFAT tra, NFAT trans, NFAT transcription complex cytosolic component, NFAT2, NFATc, NF-ATC, NFATC1, NF-ATc1, NF-ATc1.2, Nfatcb, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1, nuclear factor of activated T-cells 1, nuclear factor of activated T-cells 'c', nuclear factor of activated T-cells, cytoplasmic 1, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1, transcription factor NF-ATc
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4772
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
NFATC1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
O95644
Gene Symbols:
NFATC1
Immunogen:
Synthetic peptide within Human NFAT2 aa 894-943
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
JA81-03
Conjugate:
Unconjugated
Gene:
NFATC1
Gene Alias:
2210017P03Rik, AI449492, AV076380, MGC138448, NFAT tra, NFAT trans, NFAT transcription complex cytosolic component, NFAT2, NFATc, NF-ATC, NFATC1, NF-ATc1, NF-ATc1.2, Nfatcb, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1, nuclear factor of activated T-cells 1, nuclear factor of activated T-cells 'c', nuclear factor of activated T-cells, cytoplasmic 1, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1, transcription factor NF-ATc
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4772
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: MRP2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: Q92887
Gene Symbols: ABCC2
Immunogen: Synthetic peptide within Human MRP2 aa 1496-1545
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: JA32-01
Conjugate: Unconjugated
Gene: ABCC2
Gene Alias: ABC30, Abcc2, AI173996, ATP binding cassette subfamily C member 2, ATP-binding cassette sub-family C member 2, ATP-binding cassette, subfamily C (CFTR/MRP), member 2, ATP-binding cassette, sub-family C (CFTR/MRP), member 2, calicular multispecific organic anion transporter, canalicular multidrug resistance protein, Canalicular multispecific organic anion transporter 1, Cmoat, CMOAT1, Cmrp, DJS, Human MRP2, KIAA1010, MRP2, multidrug resistance associated protein 2, multidrug resistance protein 2, multidrug resistance-associated protein 2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1244
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
MRP2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
Q92887
Gene Symbols:
ABCC2
Immunogen:
Synthetic peptide within Human MRP2 aa 1496-1545
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
JA32-01
Conjugate:
Unconjugated
Gene:
ABCC2
Gene Alias:
ABC30, Abcc2, AI173996, ATP binding cassette subfamily C member 2, ATP-binding cassette sub-family C member 2, ATP-binding cassette, subfamily C (CFTR/MRP), member 2, ATP-binding cassette, sub-family C (CFTR/MRP), member 2, calicular multispecific organic anion transporter, canalicular multidrug resistance protein, Canalicular multispecific organic anion transporter 1, Cmoat, CMOAT1, Cmrp, DJS, Human MRP2, KIAA1010, MRP2, multidrug resistance associated protein 2, multidrug resistance protein 2, multidrug resistance-associated protein 2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1244
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Annexin A2
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P07355, P07356, Q07936
Gene Symbols: ANXA2
Immunogen: Synthetic peptide within Human Annexin A2 aa 26-75
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: JA42-30
Conjugate: Unconjugated
Gene: ANXA2
Gene Alias: 33-kDa calcimedin, 33-kDa lymphocyte Ca<2+>- binding protein, 33kDa lymphocyte Ca<2+>- binding protein, 36-kDa calelectrin, annexin 2, annexin A2, annexin A2 isoform 2, annexin II, Annexin-2, ANX2, ANX2L4, ANXA2, AW215814, CAL1H, calpactin I heavy chain, calpactin I heavy chain (p36), calpactin I heavy polypeptide, calpactin-1 heavy chain, chromobindin 8, chromobindin-8, epididymis secretory protein Li 270, HEL-S-270, LIP2, lipocortin II, LPC2, LPC2D, p36, PAP-IV, Placental anticoagulant protein IV, protein I
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 12306, 302, 56611
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Annexin A2
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P07355, P07356, Q07936
Gene Symbols:
ANXA2
Immunogen:
Synthetic peptide within Human Annexin A2 aa 26-75
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
JA42-30
Conjugate:
Unconjugated
Gene:
ANXA2
Gene Alias:
33-kDa calcimedin, 33-kDa lymphocyte Ca<2+>- binding protein, 33kDa lymphocyte Ca<2+>- binding protein, 36-kDa calelectrin, annexin 2, annexin A2, annexin A2 isoform 2, annexin II, Annexin-2, ANX2, ANX2L4, ANXA2, AW215814, CAL1H, calpactin I heavy chain, calpactin I heavy chain (p36), calpactin I heavy polypeptide, calpactin-1 heavy chain, chromobindin 8, chromobindin-8, epididymis secretory protein Li 270, HEL-S-270, LIP2, lipocortin II, LPC2, LPC2D, p36, PAP-IV, Placental anticoagulant protein IV, protein I
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
12306, 302, 56611
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid