PIMA532753

CD66e (CEA) Recombinant Rabbit Monoclonal Antibody (JM93-28), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532753-Each-of-1 In Stock ₹ 45,646.26

PIMA532753 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

CD66e (CEA)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P06731

Gene Symbols

Ceacam5

Immunogen

Human Carcinoembryonic Antigen (CEA) purified from human liver.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

JM93-28

Conjugate

Unconjugated

Gene

Ceacam5

Gene Alias

1600029H12Rik, Carcinoembryonic antigen, carcinoembryonic antigen related cell adhesion molecule 5, carcinoembryonic antigen-related cell adhesion molecule 5, CD66e, CEA, CEACAM5, Meconium antigen 100, OTTHUMP00000199033, pregnancy-specific glycoprotein 30, Psg30, sCD66e, soluble CD66e

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

1048

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • CEA (Carcino Embryonic Antigen, CD66e) is synthesized during development in the fetal gut, and re-expressed in increased amounts in intestinal carcinomas and several other tumors
  • CEA is a member of carcinoembryonic antigens, immunoglobulin supergene family and consists of a single N domain (structural homology to the immunoglobulin variable) and six immunoglobulin constant-like A (A1, A2, A3) and B domains (B1, B2, B3)
  • Antibodies to CEA are useful in identifying the origin of various metastatic adenocarcinomas and in distinguishing pulmonary adenocarcinomas (60 to 70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+)
  • CEA is a member of a large family of glycoproteins, a useful tumor marker for adenocarcinoma, and found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon
  • Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19
  • Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster
  • CEA was originally described in bile ducts of liver as biliary glycoprotein
  • Subsequently, CEA was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia
  • The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup
  • Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses
  • Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA532753

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Antigen:
CD66e (CEA)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P06731

Gene Symbols:
Ceacam5

Immunogen:
Human Carcinoembryonic Antigen (CEA) purified from human liver.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JM93-28

Conjugate:
Unconjugated

Gene:
Ceacam5

Gene Alias:
1600029H12Rik, Carcinoembryonic antigen, carcinoembryonic antigen related cell adhesion molecule 5, carcinoembryonic antigen-related cell adhesion molecule 5, CD66e, CEA, CEACAM5, Meconium antigen 100, OTTHUMP00000199033, pregnancy-specific glycoprotein 30, Psg30, sCD66e, soluble CD66e

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1048

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532756

--


Antigen:
ENO1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P04764, P06733, P17182

Gene Symbols:
ENO1

Immunogen:
Synthetic peptide within Human ENO1 aa 1-50

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat, Zebrafish

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot, Western Blot

Clone:
JM63-53

Conjugate:
Unconjugated

Gene:
ENO1

Gene Alias:
0610008I15, 2-phospho-D-glycerate hydrolase, 2-phospho-D-glycerate hydro-lyase, AL022784, alpha enolase, alpha enolase like 1, alpha-enolase, alpha-enolase, c-myc promoter-binding protein-1, c-Myc promoter binding protein, C-myc promoter-binding protein, Eno1, Eno-1, ENO1L1, enoa, Enolase 1, enolase 1, (alpha), enolase 1, alpha non-neuron, enolase-alpha, epididymis secretory protein Li 17, HEL-S-17, MBP-1, MBPB1, MPB1, MPB-1, MYC promoter-binding protein 1, NNE, Non-neural enolase, phosphopyruvate hydratase, Plasminogen-binding protein, PPH, tau-crystallin

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
13806, 2023, 24333

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532758

--


Antigen:
SETD8

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q2YDW7, Q9NQR1

Gene Symbols:
KMT5A

Immunogen:
Synthetic peptide within Human KMT5A aa 51-100

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Western Blot

Clone:
JM73-43

Conjugate:
Unconjugated

Gene:
KMT5A

Gene Alias:
2410195B05Rik, AA617402, AW536475, H4-K20-HMTase, H4-K20-HMTase KMT5A, H4-K20-HMTase SETD8, H4-K20-specific histone methyltransferase, H4K20-specific histone methyltransferase splice variant Set8b, histone methyltransferase Pr-set7/Set8, histone-lysine N-methyltransferase KMT5A, histone-lysine N-methyltransferase SETD8, KMT5A, lysine (K)-specific methyltransferase 5A, lysine methyltransferase 5A, lysine N-methyltransferase 5A, Lysine-specific methylase 5A, N-lysine methyltransferase KMT5A, N-lysine methyltransferase SETD8, PR/SET domain containing protein 8, PR/SET domain-containing protein 07, PR/SET07, PRSET7, PR-Set7, RGD1305893, SET domain containing (lysine methyltransferase) 8, SET domain containing protein 8 variant 1, SET domain containing protein 8 variant 2, SET domain-containing 8, SET domain-containing protein 8, SET07, SET8, SETD8, Unknown (protein for MGC:134426)

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
387893, 67956

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532759

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Antigen:
Angiopoietin 2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
O15123, O35462, O35608

Gene Symbols:
ANGPT2

Immunogen:
Synthetic peptide within Human Angiopoietin 2 aa 351-400

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Clone:
JM71-34

Conjugate:
Unconjugated

Gene:
ANGPT2

Gene Alias:
AGPT2, Ang2, Ang-2, angiopoietin 2, angiopoietin-2, angiopoietin-2a, angiopoietin-2B, ANGPT2, endothelial growth factor, Tie2-ligand

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11601, 285, 89805

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid