PIMA532050

CD20 Recombinant Rabbit Monoclonal Antibody (SY12-01), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532050-Each-of-1 In Stock ₹ 45,646.26

PIMA532050 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

CD20

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P11836

Gene Symbols

Ms4a1

Immunogen

Synthetic peptide within Human CD20 aa 248-297

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Non-human Primate

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

SY12-01

Conjugate

Unconjugated

Gene

Ms4a1

Gene Alias

AA960661, APY, ATOPY, B1, B-cell differentiation antigen Ly-44, B-lymphocyte antigen CD20, B-lymphocyte cell-surface antigen B1, B-lymphocyte surface antigen B1, Bp35, Cd20, CD20 antigen, CD20 cell surface protein, CD20 receptor, CVID5, EGK_06167, Fc epsilon receptor I beta chain, Fc Fragment of IgE high affinity I receptor for beta polypeptide, FCER1B, High affinity immunoglobulin epsilon receptor subunit beta, IgE Fc receptor subunit beta, IGEL, IGER, IGHER, LEU16, LEU-16, Leukocyte surface antigen Leu-16, Ly44, Ly-44, Lymphocyte antigen 44, membrane spanning 4-domains A1, membrane-spanning 4-domains subfamily A member 1, membrane-spanning 4-domains, subfamily A, member 1, membrane-spanning 4-domains, subfamily A, member 2, MGC3969, MS4A1, MS4A2, S7

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

931

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • CD20 is a non-glycosylated surface phosphoprotein that has a molecular weight range of 33-37 kDa depending on the degree of phosphorylation
  • CD20 is expressed on mature and most malignant B cells, in a subpopulation of T lymphocytes and follicular dendritic cells
  • CD20 expression on B cells is synchronous with the expression of surface IgM and it regulates transmembrane calcium conductance, cell cycle progression and B-cell proliferation
  • CD20 is also associated with lipid rafts, but the intensity of this association depends on extracellular triggering, employing CD20 conformational change, and/or BCR (B cell antigen receptor) aggregation
  • After the receptor ligation, BCR and CD20 colocalize and then rapidly dissociate before BCR endocytosis, whereas CD20 remains at the cell surface
  • CD20 serves as a useful target for antibody-mediated therapeutic depletion of B cells, as it is expressed at high levels on most B-cell malignancies, but does not become internalized or shed from the plasma membrane following monoclonal antibody treatment
  • Diseases associated with CD20 dysfunction include Ms4a1-related common variable immune deficiency.

Compare Similar Items

Show Difference

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Thermo Scientific

PIMA532050

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Antigen:
CD20

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P11836

Gene Symbols:
Ms4a1

Immunogen:
Synthetic peptide within Human CD20 aa 248-297

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
SY12-01

Conjugate:
Unconjugated

Gene:
Ms4a1

Gene Alias:
AA960661, APY, ATOPY, B1, B-cell differentiation antigen Ly-44, B-lymphocyte antigen CD20, B-lymphocyte cell-surface antigen B1, B-lymphocyte surface antigen B1, Bp35, Cd20, CD20 antigen, CD20 cell surface protein, CD20 receptor, CVID5, EGK_06167, Fc epsilon receptor I beta chain, Fc Fragment of IgE high affinity I receptor for beta polypeptide, FCER1B, High affinity immunoglobulin epsilon receptor subunit beta, IgE Fc receptor subunit beta, IGEL, IGER, IGHER, LEU16, LEU-16, Leukocyte surface antigen Leu-16, Ly44, Ly-44, Lymphocyte antigen 44, membrane spanning 4-domains A1, membrane-spanning 4-domains subfamily A member 1, membrane-spanning 4-domains, subfamily A, member 1, membrane-spanning 4-domains, subfamily A, member 2, MGC3969, MS4A1, MS4A2, S7

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
931

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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PIMA532051

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Antigen:
PCNA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P04961, P12004, P17918

Gene Symbols:
Pcna

Immunogen:
Synthetic peptide within Human PCNA aa 88-137

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SY12-07

Conjugate:
Unconjugated

Gene:
Pcna

Gene Alias:
ATLD2, cb16, Cyclin, DNA polymerase delta auxiliary protein, etID36690.10, fa28e03, fb36g03, HGCN8729, hypothetical protein LOC515499, MGC8367, Pcna, pcna protein, Pcna/cyclin, PCNAR, POL30, Proliferating cell nuclear antigen, wu:fa28e03, wu:fb36g03, YBR0811, YBR088C

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
18538, 25737, 5111

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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PIMA532053

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Antigen:
V5 Tag

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Synthetic peptide immune sequence is CGKPIPNPLLGLDST

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Tag

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
SY30-01

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
simian virus 5 antibody, SPV5gp2, sv5, V5, v-5, V5 Epitope Tag

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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PIMA532055

--


Antigen:
CDK1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P06493, P11440, P39951

Gene Symbols:
CDK1

Immunogen:
Synthetic peptide within Human CDK1 aa 228-277

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SM01-44

Conjugate:
Unconjugated

Gene:
CDK1

Gene Alias:
5363, ABL1, cdc, CDC2, cdc-2, cdc2 kinase, CDC28A, Cdc2a, cdc2-a, cdc2Dm, cdc2x1.1, CDCDm, CDK1, Cdk-1, cdk1.S, CDK1/CDC2, CDK1-A, cdk1-b, Cdk1-PA, CDKN1, cell cycle controller CDC2, cell cycle p34 CDC2 kinase protein, cell division control, cell division control protein 2 homolog, Cell division control protein 2 homolog 1, cell division control protein 2-A, cell division cycle 2 homolog A, cell division cycle 2 like, cell division cycle 2, G1 to S and G2 to M, Cell division cycle control protein 2, cell division cycle control protein 2a, cell division protein kinase 1, Cell division protein kinase 1-A, CG5363, CG5363-PA, cyclin dependent kinase, cyclin dependent kinase 1, cyclin-dependent kinase, Cyclin-dependent kinase 1, cyclin-dependent kinase 1 S homeolog, cyclin-dependent kinase 1-A, D2366, Dcdc2, dCdk1, DKFZp686L20222, Dm cdc2, Dmcdc2, DmCdk1, Dmel\CG5363, Dmel_CG5363, DNA polymerase delta catalytic subunit, DNA polymerase III, DNA-directed DNA polymerase delta POL3, group 4, HPR6, KCIP-1, l(2)31Eh, LD38718p, maturation-promoting factor, MGC111195, MGC53829, MPF, OTTHUMP00000019660, P34 CDK1, P34 MGC111195, p34 protein kinase, p34 protein kinase 1, p34<CDC2>, p34cdc2, p34-cdc2 homologue, POL3, Protein 1054, protein 2, PSTAIR, TEX1, unnamed protein product, xcdc2, XELAEV_18036802mg, YDL102W

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12534, 54237, 983

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid