PIMA533053
CD20 Recombinant Rabbit Monoclonal Antibody (RM272), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533053-Each-of-1 | In Stock | ₹ 48,555.30 |
PIMA533053 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,555.30
GST (18%): ₹ 8,739.954
Total Price: ₹ 57,295.254
Antigen
CD20
Classification
Recombinant Monoclonal
Concentration
0.1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.
P11836
Gene Symbols
Ms4a1
Immunogen
A peptide corresponding to the C-terminus of human CD20.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
RM272
Conjugate
Unconjugated
Gene
Ms4a1
Gene Alias
AA960661, APY, ATOPY, B1, B-cell differentiation antigen Ly-44, B-lymphocyte antigen CD20, B-lymphocyte cell-surface antigen B1, B-lymphocyte surface antigen B1, Bp35, Cd20, CD20 antigen, CD20 cell surface protein, CD20 receptor, CVID5, EGK_06167, Fc epsilon receptor I beta chain, Fc Fragment of IgE high affinity I receptor for beta polypeptide, FCER1B, High affinity immunoglobulin epsilon receptor subunit beta, IgE Fc receptor subunit beta, IGEL, IGER, IGHER, LEU16, LEU-16, Leukocyte surface antigen Leu-16, Ly44, Ly-44, Lymphocyte antigen 44, membrane spanning 4-domains A1, membrane-spanning 4-domains subfamily A member 1, membrane-spanning 4-domains, subfamily A, member 1, membrane-spanning 4-domains, subfamily A, member 2, MGC3969, MS4A1, MS4A2, S7
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
931
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- Specificity: reacts to the cytoplasmic domain of human CD20
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- CD20 is a non-glycosylated surface phosphoprotein that has a molecular weight range of 33-37 kDa depending on the degree of phosphorylation
- CD20 is expressed on mature and most malignant B cells, in a subpopulation of T lymphocytes and follicular dendritic cells
- CD20 expression on B cells is synchronous with the expression of surface IgM and it regulates transmembrane calcium conductance, cell cycle progression and B-cell proliferation
- CD20 is also associated with lipid rafts, but the intensity of this association depends on extracellular triggering, employing CD20 conformational change, and/or BCR (B cell antigen receptor) aggregation
- After the receptor ligation, BCR and CD20 colocalize and then rapidly dissociate before BCR endocytosis, whereas CD20 remains at the cell surface
- CD20 serves as a useful target for antibody-mediated therapeutic depletion of B cells, as it is expressed at high levels on most B-cell malignancies, but does not become internalized or shed from the plasma membrane following monoclonal antibody treatment
- Diseases associated with CD20 dysfunction include Ms4a1-related common variable immune deficiency.
Compare Similar Items
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Antigen: CD20
Classification: Recombinant Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: P11836
Gene Symbols: Ms4a1
Immunogen: A peptide corresponding to the C-terminus of human CD20.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: RM272
Conjugate: Unconjugated
Gene: Ms4a1
Gene Alias: AA960661, APY, ATOPY, B1, B-cell differentiation antigen Ly-44, B-lymphocyte antigen CD20, B-lymphocyte cell-surface antigen B1, B-lymphocyte surface antigen B1, Bp35, Cd20, CD20 antigen, CD20 cell surface protein, CD20 receptor, CVID5, EGK_06167, Fc epsilon receptor I beta chain, Fc Fragment of IgE high affinity I receptor for beta polypeptide, FCER1B, High affinity immunoglobulin epsilon receptor subunit beta, IgE Fc receptor subunit beta, IGEL, IGER, IGHER, LEU16, LEU-16, Leukocyte surface antigen Leu-16, Ly44, Ly-44, Lymphocyte antigen 44, membrane spanning 4-domains A1, membrane-spanning 4-domains subfamily A member 1, membrane-spanning 4-domains, subfamily A, member 1, membrane-spanning 4-domains, subfamily A, member 2, MGC3969, MS4A1, MS4A2, S7
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 931
Content And Storage: -20°C
Form: Liquid
Antigen:
CD20
Classification:
Recombinant Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
P11836
Gene Symbols:
Ms4a1
Immunogen:
A peptide corresponding to the C-terminus of human CD20.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
RM272
Conjugate:
Unconjugated
Gene:
Ms4a1
Gene Alias:
AA960661, APY, ATOPY, B1, B-cell differentiation antigen Ly-44, B-lymphocyte antigen CD20, B-lymphocyte cell-surface antigen B1, B-lymphocyte surface antigen B1, Bp35, Cd20, CD20 antigen, CD20 cell surface protein, CD20 receptor, CVID5, EGK_06167, Fc epsilon receptor I beta chain, Fc Fragment of IgE high affinity I receptor for beta polypeptide, FCER1B, High affinity immunoglobulin epsilon receptor subunit beta, IgE Fc receptor subunit beta, IGEL, IGER, IGHER, LEU16, LEU-16, Leukocyte surface antigen Leu-16, Ly44, Ly-44, Lymphocyte antigen 44, membrane spanning 4-domains A1, membrane-spanning 4-domains subfamily A member 1, membrane-spanning 4-domains, subfamily A, member 1, membrane-spanning 4-domains, subfamily A, member 2, MGC3969, MS4A1, MS4A2, S7
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
931
Content And Storage:
-20°C
Form:
Liquid
Antigen: CD56 (NCAM)
Classification: Recombinant Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: P13591, P13595
Gene Symbols: Ncam1
Immunogen: A peptide corresponding to the C-terminus of human CD56.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: RM315
Conjugate: Unconjugated
Gene: Ncam1
Gene Alias: adhesion molecule, antigen recognized by monoclonal antibody 5.1H11, Cd56, CD-56, CD56 120 kDa GPI-linked isoform, CD56 140 kDa isoform, CD56 140 kDa VASE isoform, E NCAM, E-NCAM, MSK39, N CAM1, NCAM, N-CAM, Ncam1, N-CAM-1, NCAM-1, NCAMC, NCAM-C, neural cell adhesion molecule, Neural cell adhesion molecule 1, neural cell adhesion molecule, NCAM, sCD56, sNCAM, soluble CD56, soluble NCAM
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 17967, 4684
Content And Storage: -20°C
Form: Liquid
Antigen:
CD56 (NCAM)
Classification:
Recombinant Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
P13591, P13595
Gene Symbols:
Ncam1
Immunogen:
A peptide corresponding to the C-terminus of human CD56.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
RM315
Conjugate:
Unconjugated
Gene:
Ncam1
Gene Alias:
adhesion molecule, antigen recognized by monoclonal antibody 5.1H11, Cd56, CD-56, CD56 120 kDa GPI-linked isoform, CD56 140 kDa isoform, CD56 140 kDa VASE isoform, E NCAM, E-NCAM, MSK39, N CAM1, NCAM, N-CAM, Ncam1, N-CAM-1, NCAM-1, NCAMC, NCAM-C, neural cell adhesion molecule, Neural cell adhesion molecule 1, neural cell adhesion molecule, NCAM, sCD56, sNCAM, soluble CD56, soluble NCAM
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
17967, 4684
Content And Storage:
-20°C
Form:
Liquid
Antigen: Cytokeratin 19
Classification: Recombinant Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: P08727
Gene Symbols: KRT19
Immunogen: A peptide corresponding to the C-terminus of human CK-19 (Cytokeratin-19).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: RM364
Conjugate: Unconjugated
Gene: KRT19
Gene Alias: 40-kDa keratin intermediate filament, AI663979, C K1CS, CK 19, CK19, CK-19, cytokeratin 19, cytokeratin-19, EndoC, K19, K1CS, Ka19, keratin 19, keratin 19, type I, keratin complex 1, acidic, gene 19, keratin, type I cytoskeletal 19, keratin, type I, 40-kd, keratin-19, Krt-1.19, Krt1-19, Krt19, LOC100344434, MGC15366, Type I keratin Ka19
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3880
Content And Storage: -20°C
Form: Liquid
Antigen:
Cytokeratin 19
Classification:
Recombinant Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
P08727
Gene Symbols:
KRT19
Immunogen:
A peptide corresponding to the C-terminus of human CK-19 (Cytokeratin-19).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
RM364
Conjugate:
Unconjugated
Gene:
KRT19
Gene Alias:
40-kDa keratin intermediate filament, AI663979, C K1CS, CK 19, CK19, CK-19, cytokeratin 19, cytokeratin-19, EndoC, K19, K1CS, Ka19, keratin 19, keratin 19, type I, keratin complex 1, acidic, gene 19, keratin, type I cytoskeletal 19, keratin, type I, 40-kd, keratin-19, Krt-1.19, Krt1-19, Krt19, LOC100344434, MGC15366, Type I keratin Ka19
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3880
Content And Storage:
-20°C
Form:
Liquid
Antigen: GFAP
Classification: Recombinant Monoclonal
Concentration: 0.05 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: P03995, P14136
Gene Symbols: GFAP
Immunogen: A peptide corresponding to the N-terminus of human GFAP.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: RM246
Conjugate: Unconjugated
Gene: GFAP
Gene Alias: 6330404F12Rik, 65 kDa glutamic acid decarboxylase, AI836096, ALXDRD, Astrocyte or Intermediate Filament Protein, cb345, class III intermediate filament protein, etID36982.3, FLJ45472, GAD(65), Gad2, Gad-2, GAD65, GAD-65, GFAP, GFAP epsilon, gfap protein, gfapl, glial fibrillary acidic protein, Glial Fibrillary Acidic Protein (GFAP), glial fibrillary acidic protein alpha, glutamate decarboxylase 2, Glutamate decarboxylase 65 kDa isoform, glutamic acid decarboxylase 2, I79_011607, intermediate filament, intermediate filament protein, intermediate filament protein, GFAP, Unknown (protein for MGC:139638), wu:fb34h11, wu:fk42c12, xx:af506734, zgc:110485, zGFAP, intermediate filament protein, zrf-1 antigen
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 14580, 2670
Content And Storage: -20°C
Form: Liquid
Antigen:
GFAP
Classification:
Recombinant Monoclonal
Concentration:
0.05 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
P03995, P14136
Gene Symbols:
GFAP
Immunogen:
A peptide corresponding to the N-terminus of human GFAP.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
RM246
Conjugate:
Unconjugated
Gene:
GFAP
Gene Alias:
6330404F12Rik, 65 kDa glutamic acid decarboxylase, AI836096, ALXDRD, Astrocyte or Intermediate Filament Protein, cb345, class III intermediate filament protein, etID36982.3, FLJ45472, GAD(65), Gad2, Gad-2, GAD65, GAD-65, GFAP, GFAP epsilon, gfap protein, gfapl, glial fibrillary acidic protein, Glial Fibrillary Acidic Protein (GFAP), glial fibrillary acidic protein alpha, glutamate decarboxylase 2, Glutamate decarboxylase 65 kDa isoform, glutamic acid decarboxylase 2, I79_011607, intermediate filament, intermediate filament protein, intermediate filament protein, GFAP, Unknown (protein for MGC:139638), wu:fb34h11, wu:fk42c12, xx:af506734, zgc:110485, zGFAP, intermediate filament protein, zrf-1 antigen
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
14580, 2670
Content And Storage:
-20°C
Form:
Liquid