PIMA532627

TDP-43 Recombinant Rabbit Monoclonal Antibody (JM51-10), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532627-Each-of-1 In Stock ₹ 51,036.54

PIMA532627 - Each of 1

₹ 51,036.54

In Stock

Quantity

1

Base Price: ₹ 51,036.54

GST (18%): ₹ 9,186.577

Total Price: ₹ 60,223.117

Antigen

TDP-43

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

Q13148, Q921F2

Gene Symbols

TARDBP

Immunogen

Synthetic peptide within Human TDP43 aa 354-390

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat, Zebrafish

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot, Western Blot

Clone

JM51-10

Conjugate

Unconjugated

Gene

TARDBP

Gene Alias

1190002A23Rik, ALS10, C85084, hypothetical protein, OTTHUMP00000002171, OTTHUMP00000002173, RCJMB04_5g9, RP4-635E18.2, TAR DNA binding protein, TAR DNA binding protein L homeolog, TAR DNA-binding protein 43, TAR DNA-binding protein-43, tardbp, tardbp.L, Tdp43, TDP-43, wu:fb77f02, wu:fc52g10, XELAEV_18035188mg

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

230908, 23435, 298648, 325052

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • TDP43 was first identified as a novel cellular protein that binds to HIV-1 virus TAR DNA sequence motifs and acts a transcriptional repressor to the HIV-1 LTR
  • Later experiments revealed that TDP43 also regulates the splicing of exon 9 of the cystic fibrosis transmembrane conductance regular (CFTR), most likely through the association with the UG repeats at the 3&quotee; splice site
  • A hyperphosphorylated, ubiquitinated, and cleaved form of TDP43 known as pathologic TDP43 is the major disease protein in ubiquitin-positive, tau-, and alpha-synuclein-negative frontotemporal dementia (FLTD-U)
  • TDP43 is not related to TRBP1, and RNA binding protein that binds HIV-1 TAR RNA sequences.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA532627

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Antigen:
TDP-43

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q13148, Q921F2

Gene Symbols:
TARDBP

Immunogen:
Synthetic peptide within Human TDP43 aa 354-390

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat, Zebrafish

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot, Western Blot

Clone:
JM51-10

Conjugate:
Unconjugated

Gene:
TARDBP

Gene Alias:
1190002A23Rik, ALS10, C85084, hypothetical protein, OTTHUMP00000002171, OTTHUMP00000002173, RCJMB04_5g9, RP4-635E18.2, TAR DNA binding protein, TAR DNA binding protein L homeolog, TAR DNA-binding protein 43, TAR DNA-binding protein-43, tardbp, tardbp.L, Tdp43, TDP-43, wu:fb77f02, wu:fc52g10, XELAEV_18035188mg

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
230908, 23435, 298648, 325052

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532630

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Antigen:
Endothelin B Receptor

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P24530

Gene Symbols:
EDNRB

Immunogen:
Synthetic peptide within Human Endothelin B Receptor aa 58-91

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Zebrafish

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Clone:
JM74-10

Conjugate:
Unconjugated

Gene:
EDNRB

Gene Alias:
ABCDS, AU022549, Ednra, Ednrb, endothelin B receptor, endothelin receptor non-selective type, endothelin receptor subtype B1, endothelin receptor type B, endothelin-B receptor, ETb, ET-B, Etb receptor, Et-b receptor, ETB1, ETBR, ET-BR, Et-b-r, Etb-svr, ETRB, ET-RB, ETR-b, HSCR, HSCR2, piebald, RP11-318G21.1, Sox10m1, WS4A

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1910

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532631

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Antigen:
RAC1/RAC2/RAC3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P15153, P60763, P60764, P63000, P63001, Q05144, Q6RUV5

Gene Symbols:
Rac1, RAC2, Rac3

Immunogen:
Recombinant full length protein of Human RAC1 aa 1-192

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JM11-29

Conjugate:
Unconjugated

Gene:
Rac3

Gene Alias:
AI323801, AI452260, AL023026, Cell migration-inducing gene 5 protein, D5Ertd559e, EN-7, EN-7 protein, GTPase, Gx, HSPC022, MIG5, p21-Rac1, p21-Rac2, p21-Rac3, protein EN-7, rac, Rac family small GTPase 1, Rac family small GTPase 1 L homeolog, Rac family small GTPase 2, Rac family small GTPase 3, rac1, Rac-1, rac1.L, Rac1B, RAC2, Rac3, Ras-like protein TC25, RAS-related C3 botulinum substrate 1, RAS-related C3 botulinum substrate 2, RAS-related C3 botulinum substrate 3, ras-related C3 botulinum toxin substrate 1, ras-related C3 botulinum toxin substrate 1 (rho family small GTP binding protein Rac1), ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1), ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) L homeolog, ras-related C3 botulinum toxin substrate 2, ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2), ras-related C3 botulinum toxin substrate 3, ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3), Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2), rho family, small GTP binding protein Rac1, rho family, small GTP binding protein Rac3, small G protein, TC25, TC-25, XELAEV_18045321mg, Xrac

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
170758, 19353, 19354, 363875, 366957, 5879, 5880, 5881, 688319

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532632

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Antigen:
TIMP2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P16035

Gene Symbols:
TIMP2

Immunogen:
Synthetic peptide within Human TIMP2 aa 171-220.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot, Western Blot

Clone:
JM87-10

Conjugate:
Unconjugated

Gene:
TIMP2

Gene Alias:
Collagenase inhibitor, CSC-21K, D11Bwg1104e, DDC8, etID32613.12, fa96h09, Metalloproteinase inhibitor 2, metalloproteinase inhibitor 2a, metalloproteinase inhibitor precursor, metalloproteinase inhibitor TIMP-2, metalloproteinase-2, similar to metalloproteinase inhibitor, testicular secretory protein Li 57, TIMP 2, TIMP metallopeptidase inhibitor 2, TIMP metallopeptidase inhibitor 2a, TIMP2, Timp-2, TIMP-2 protein, timp2a, tissue inhibitor of matrix metalloproteinase-2, tissue inhibitor of metalloproteinase 2, tissue inhibitor of metalloproteinase 2 precursor, tissue inhibitor of metalloproteinase 2a, tissue inhibitor of metalloproteinase-2, tissue inhibitor of metalloproteinase-2 precursor, tissue inhibitor of metalloproteinases 2, tissue inhibitor of mettaloproteinase 2, wu:fa96h09, zgc:136726

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7077

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid