PIMA533008
IL-22 Monoclonal Antibody (7F2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533008-Each-of-1 | In Stock | ₹ 45,218.46 |
PIMA533008 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,218.46
GST (18%): ₹ 8,139.323
Total Price: ₹ 53,357.783
Antigen
IL-22
Classification
Monoclonal
Concentration
500 μg/mL
Formulation
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.
Q9GZX6
Gene Symbols
IL22
Immunogen
E.coli-derived human IL-22 recombinant protein (Position: A34-I179).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Western Blot
Clone
7F2
Conjugate
Unconjugated
Gene
IL22
Gene Alias
Cytokine Zcyto18, EGK_03903, il 22, IL-10-related T-cell-derived inducible factor, IL-10-related T-cell-derived-inducible factor, IL-21, IL22, IL-22, Il22a, IL-22a, IL-D110, ILN, ILTIF, IL-TIF, ILTIF alpha, IL-TIF alpha, ILTIFa, Interleukin, interleukin 10-related T cell-derived inducible factor, interleukin 22, Interleukin22, interleukin-22, Interleukin-22a, RGD1561292, TIFa, TIFIL-23, UNQ3099/PRO10096, ZCYTO18
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
50616
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Lyophilized
Related Products
Description
- Human IL-22 shares 81.4% amino acid (aa) sequence identity with mouse IL-22
- Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
- IL-22 also known as IL-10-related T-cell derived inducible factor, is an alpha helical cytokine and is considered a member of the IFN-IL-10 family, which includes IL-19, IL-20, IL-24, IL-26, IL-28, IL-29, and the type I and II interferons
- IL-22 is produced mainly by activated T cells and NK cells
- In humans, the IL-22 gene is located on the q arm of chromosome 12, and is structurally related to IL10
- IL-22 acts by engaging the heterodimeric receptor complex consisting of primary receptor IL-22R1 and accessory receptor IL-10R2
- IL-22R1 also binds IL-20 and IL-24; IL-10R2 also binds IL-10, IL-27, IL-28, and IL-29
- Binding of IL-22 to its receptor complex induces signal transduction, particularly via the JAK-STAT pathway
- In addition to the membrane-bound IL-22R1/IL-10R2 complex, a soluble single-chain IL-22 receptor termed IL-22BP has been found to antagonize IL-22 binding and signaling
- IL-22 appears not to directly influence immune cells, and major targets of the cytokine appear to be nonimmune cells, such as cells of the skin, digestive and respiratory system, as well as hepatocytes, and keratinocytes
- IL-22 has been described as an effector cytokine of the Th17 lineage
- Along with IL-17A and IL-17F, IL-22 regulates genes associated with innate immunity of the skin
- IL-17A, IL-17F and IL-22 are all co-expressed by Th17 cells, however, they are differentially regulated
- The effects of IL-22 include induction of acute phase reactants and antimicrobial proteins, as well as increasing the mobility of keratinocytes
- IL-22 is highly expressed during chronic inflammation, and found to activate intracellular kinases and transcription factors
- IL-22 is critical for host defense against infections of extracellular pathogens, and promotes wound-healing responses
- IL-22 is upregulated in activated T cells
- IL-22 has been reported to mediate IL-23-induced acanthosis and dermal inflammation through activation of STAT3.
Compare Similar Items
Show Difference
Antigen: IL-22
Classification: Monoclonal
Concentration: 500 μg/mL
Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.: Q9GZX6
Gene Symbols: IL22
Immunogen: E.coli-derived human IL-22 recombinant protein (Position: A34-I179).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Western Blot
Clone: 7F2
Conjugate: Unconjugated
Gene: IL22
Gene Alias: Cytokine Zcyto18, EGK_03903, il 22, IL-10-related T-cell-derived inducible factor, IL-10-related T-cell-derived-inducible factor, IL-21, IL22, IL-22, Il22a, IL-22a, IL-D110, ILN, ILTIF, IL-TIF, ILTIF alpha, IL-TIF alpha, ILTIFa, Interleukin, interleukin 10-related T cell-derived inducible factor, interleukin 22, Interleukin22, interleukin-22, Interleukin-22a, RGD1561292, TIFa, TIFIL-23, UNQ3099/PRO10096, ZCYTO18
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 50616
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Antigen:
IL-22
Classification:
Monoclonal
Concentration:
500 μg/mL
Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.:
Q9GZX6
Gene Symbols:
IL22
Immunogen:
E.coli-derived human IL-22 recombinant protein (Position: A34-I179).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Western Blot
Clone:
7F2
Conjugate:
Unconjugated
Gene:
IL22
Gene Alias:
Cytokine Zcyto18, EGK_03903, il 22, IL-10-related T-cell-derived inducible factor, IL-10-related T-cell-derived-inducible factor, IL-21, IL22, IL-22, Il22a, IL-22a, IL-D110, ILN, ILTIF, IL-TIF, ILTIF alpha, IL-TIF alpha, ILTIFa, Interleukin, interleukin 10-related T cell-derived inducible factor, interleukin 22, Interleukin22, interleukin-22, Interleukin-22a, RGD1561292, TIFa, TIFIL-23, UNQ3099/PRO10096, ZCYTO18
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
50616
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Antigen: CD2AP
Classification: Monoclonal
Concentration: 500 μg/mL
Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.: F1LRS8, Q9JLQ0, Q9Y5K6
Gene Symbols: CD2AP
Immunogen: E.coli-derived human CD2AP recombinant protein (Position: K253-K337).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 5F8
Conjugate: Unconjugated
Gene: CD2AP
Gene Alias: adapter protein CMS, AL024079, C78928, Cas ligand with multiple SH3 domains, Cas ligand with multiple Src homology 3 (SH3) domains, CD2 associated protein, Cd2ap, CD2-associated protein, CMS, mesenchyme to epithelium transition protein, SH3 domains, mesenchyme-to-epithelium transition protein with SH3 domains 1, Mets1, METS-1, SH3 domain-containing adapter protein, SH3 domain-containing adaptor protein METS-1
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12488, 23607, 316258
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Antigen:
CD2AP
Classification:
Monoclonal
Concentration:
500 μg/mL
Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.:
F1LRS8, Q9JLQ0, Q9Y5K6
Gene Symbols:
CD2AP
Immunogen:
E.coli-derived human CD2AP recombinant protein (Position: K253-K337).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
5F8
Conjugate:
Unconjugated
Gene:
CD2AP
Gene Alias:
adapter protein CMS, AL024079, C78928, Cas ligand with multiple SH3 domains, Cas ligand with multiple Src homology 3 (SH3) domains, CD2 associated protein, Cd2ap, CD2-associated protein, CMS, mesenchyme to epithelium transition protein, SH3 domains, mesenchyme-to-epithelium transition protein with SH3 domains 1, Mets1, METS-1, SH3 domain-containing adapter protein, SH3 domain-containing adaptor protein METS-1
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12488, 23607, 316258
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Antigen: Fumarase
Classification: Monoclonal
Concentration: 500 μg/mL
Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.: P07954, P14408, P97807
Gene Symbols: FH, Fh1
Immunogen: A synthetic peptide corresponding to a sequence of human FH (YDKAAKIAKTAH KNGSTLKETAIELGYLTAEQFDEWVKPKDMLGPK).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG2a
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 9D8
Conjugate: Unconjugated
Gene: FH
Gene Alias: EF-3, Fh, Fh1, Fh-1, FMRD, fumarase, fumarate hydratase, fumarate hydratase 1, fumarate hydratase, mitochondrial, HLRCC, LRCC, MCL, MCUL1
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14193, 14194, 2271, 24368
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Antigen:
Fumarase
Classification:
Monoclonal
Concentration:
500 μg/mL
Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.:
P07954, P14408, P97807
Gene Symbols:
FH, Fh1
Immunogen:
A synthetic peptide corresponding to a sequence of human FH (YDKAAKIAKTAH KNGSTLKETAIELGYLTAEQFDEWVKPKDMLGPK).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
9D8
Conjugate:
Unconjugated
Gene:
FH
Gene Alias:
EF-3, Fh, Fh1, Fh-1, FMRD, fumarase, fumarate hydratase, fumarate hydratase 1, fumarate hydratase, mitochondrial, HLRCC, LRCC, MCL, MCUL1
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14193, 14194, 2271, 24368
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Antigen: Acetylated Lysine
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: __
Gene Symbols: __
Immunogen: Acetyllysine-BSA.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Chemical
Product Type: Antibody
Isotype: IgG
Applications: ChIP Assay, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Luminex, Western Blot
Clone: RM101
Conjugate: Unconjugated
Gene: __
Gene Alias: Acetyl Lysine, Acetylated Lysine, Acetyllysine
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20°C
Form: Liquid
Antigen:
Acetylated Lysine
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Acetyllysine-BSA.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Chemical
Product Type:
Antibody
Isotype:
IgG
Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Luminex, Western Blot
Clone:
RM101
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
Acetyl Lysine, Acetylated Lysine, Acetyllysine
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20°C
Form:
Liquid