PIMA533119

Bcl-2 Recombinant Rabbit Monoclonal Antibody (2C6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA533119-Each-of-1 In Stock ₹ 48,640.86

PIMA533119 - Each of 1

₹ 48,640.86

In Stock

Quantity

1

Base Price: ₹ 48,640.86

GST (18%): ₹ 8,755.355

Total Price: ₹ 57,396.215

Antigen

Bcl-2

Classification

Recombinant Monoclonal

Concentration

0.49 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

P10415, P10417, P49950

Gene Symbols

Bcl2

Immunogen

Synthesized Bcl-2 Antibody (48-81aa)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone

2C6

Conjugate

Unconjugated

Gene

Bcl2

Gene Alias

apoptosis regulator Bcl-2, AW986256, B cell leukemia/lymphoma 2, B cell lymphoma 2 associated oncogene, B-cell CLL/lymphoma 2, B-cell leukemia/lymphoma 2, Bcl 2, BCL2, bcl-2, BCL2 apoptosis regulator, Bcl-2 protein, BCL2, apoptosis regulator, Bcl2-like protein, C430015F12Rik, D630044D05Rik, D830018M01Rik, OTTHUMP00000163680, PPP1R50, protein phosphatase 1, regulatory subunit 50

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

12043, 24224, 596

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

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Description

  • BCL-2 is a key regulator of apoptosis that functions to either inhibit or promote cell death
  • The BCL-2 family members are also characterized by dimerizing to further modulate apoptosis
  • Bag1, for example, has been found to form a heterodimer with BCL-2 resulting in the enhancement of the anti-apoptotic effect of BCL-2
  • Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis
  • Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells
  • Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma
  • In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative
  • Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends
  • The overexpression of BCL-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.

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Img

Thermo Scientific

PIMA533119

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Antigen:
Bcl-2

Classification:
Recombinant Monoclonal

Concentration:
0.49 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P10415, P10417, P49950

Gene Symbols:
Bcl2

Immunogen:
Synthesized Bcl-2 Antibody (48-81aa)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
2C6

Conjugate:
Unconjugated

Gene:
Bcl2

Gene Alias:
apoptosis regulator Bcl-2, AW986256, B cell leukemia/lymphoma 2, B cell lymphoma 2 associated oncogene, B-cell CLL/lymphoma 2, B-cell leukemia/lymphoma 2, Bcl 2, BCL2, bcl-2, BCL2 apoptosis regulator, Bcl-2 protein, BCL2, apoptosis regulator, Bcl2-like protein, C430015F12Rik, D630044D05Rik, D830018M01Rik, OTTHUMP00000163680, PPP1R50, protein phosphatase 1, regulatory subunit 50

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
12043, 24224, 596

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Img

Thermo Scientific

PIMA533120

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Antigen:
Phospho-B-Raf (Thr401)

Classification:
Recombinant Monoclonal

Concentration:
1.3 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P15056

Gene Symbols:
BRAF

Immunogen:
A synthesized peptide derived from human Phospho-BRAF (T401)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
4B9

Conjugate:
Unconjugated

Gene:
BRAF

Gene Alias:
94 kDa B-raf protein, 9930012E13Rik, AA120551, AA387315, AA473386, Braf, B-raf, B-raf protein, B-raf protein isoform 1, B-raf protein isoform 2, B-Raf proto-oncogene serine/threonine-protein kinase, B-Raf proto-oncogene serine/threonine-protein kinase (p94), B-Raf proto-oncogene, serine/threonine kinase, Braf transforming gene, BRAF1, B-RAF1, Braf2, Braf-2, C230098H17, C87398, C-RMIL, D6Ertd631e, FLJ95109, MGC126806, murine sarcoma viral (v-raf) oncogene homolog B1, NS7, p94, Proto-oncogene B-Raf, proto-oncogene c-Rmil, RAFB1, RMIL, rmil serine/threonine-protein kinase, serine/threonine kinase, serine/threonine-protein kinase B-raf, Serine/threonine-protein kinase Rmil, v-raf murine sarcoma viral oncogene homolog B, v-raf murine sarcoma viral oncogene homolog B1

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
673

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Img

Thermo Scientific

PIMA533121

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Antigen:
Caspase 9

Classification:
Recombinant Monoclonal

Concentration:
1.75 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P55211

Gene Symbols:
CASP9

Immunogen:
A synthesized peptide derived from human CASP9

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
2D5

Conjugate:
Unconjugated

Gene:
CASP9

Gene Alias:
25 kDa caspase-9 dominant negative protein, AI115399, APAF3, APAF-3, apoptotic protease activating factor 3, apoptotic protease MCH-6, Apoptotic protease-activating factor 3, AW493809, cas9, CASP 9, CASP9, CASP-9, Casp9_v1, Casp-9-CTD, caspase 9, caspase 9, apoptosis-related cysteine peptidase, caspase 9, apoptosis-related cysteine protease, Caspase9, caspase-9, caspase-9 dominant negative form, Caspase-9 precursor, Caspase-9 subunit p10, Caspase-9 subunit p35, CASPASE-9c, caspase-9-carboxyl-terminal divergent, CTD, Ice-Lap6, ICE-like apoptotic protease 6, Mch6, OTTHUMP00000002324, PPP1R56, protein phosphatase 1, regulatory subunit 56, RNCASP9, RP11-265F14.3

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
842

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Img

Thermo Scientific

PIMA533122

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Antigen:
CCR9

Classification:
Recombinant Monoclonal

Concentration:
1.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P51686, Q9WUT7

Gene Symbols:
Ccr9

Immunogen:
A synthesized peptide derived from human CCR9

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
4G2

Conjugate:
Unconjugated

Gene:
Ccr9

Gene Alias:
A130091K22Rik, C-C chemokine receptor type 9, C-C CKR-9, C-C motif chemokine receptor 9, CC-CKR-9, Ccr9, CCR-9, CDw199, CDw199 antigen, chemokine (C-C motif) receptor 9, chemokine C-C receptor 10, Cmkbr10, G protein-coupled receptor 28, GPR28, GPR-9-6, G-protein coupled receptor 28

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10803, 12769

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid