PIMA533175
Phospho-IRF3 (Ser386) Recombinant Rabbit Monoclonal Antibody (4H10), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533175-Each-of-1 | In Stock | ₹ 48,640.86 |
PIMA533175 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,640.86
GST (18%): ₹ 8,755.355
Total Price: ₹ 57,396.215
Antigen
Phospho-IRF3 (Ser386)
Classification
Recombinant Monoclonal
Concentration
1.03 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
Q14653
Gene Symbols
IRF3
Immunogen
A synthesized peptide derived from human Phospho-IRF3 (S386)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ELISA, Western Blot
Clone
4H10
Conjugate
Unconjugated
Gene
IRF3
Gene Alias
C920001K05Rik, IIAE7, Interferon regulatory factor 3, IRF3, IRF-3, IRF3 (phospho S386), IRF3 (pS386), IRF3 (pSer386), IRF3 phospho, IRF3 phospho S386, IRF3 phospho Ser386, phospho IRF3
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
3661
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Related Products
Description
- IFR3 (interferon regulatory factor 3) is a key transcriptional regulator of type I interferon (IFN)-dependent immune responses
- It plays a critical role in the innate immune response against DNA and RNA viruses
- IFR3 regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters
- It acts as a more potent activator of the IFN-beta gene than the IFN-alpha gene and plays a critical role in both the early and late phases of the IFNA/B gene induction
- IFR3 is found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA, or toll-like receptor signaling
- It is phosphorylated by IKBKE and TBK1 kinases
- This induces a conformational change, leading to its dimerization and nuclear localization and association with CREB binding protein to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of the type I IFN and ISG genes
- Mutations in the gene can result in encephalopathy, acute, infection-induced, herpes-specific 7.
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Antigen: Phospho-IRF3 (Ser386)
Classification: Recombinant Monoclonal
Concentration: 1.03 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: Q14653
Gene Symbols: IRF3
Immunogen: A synthesized peptide derived from human Phospho-IRF3 (S386)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Western Blot
Clone: 4H10
Conjugate: Unconjugated
Gene: IRF3
Gene Alias: C920001K05Rik, IIAE7, Interferon regulatory factor 3, IRF3, IRF-3, IRF3 (phospho S386), IRF3 (pS386), IRF3 (pSer386), IRF3 phospho, IRF3 phospho S386, IRF3 phospho Ser386, phospho IRF3
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 3661
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Antigen:
Phospho-IRF3 (Ser386)
Classification:
Recombinant Monoclonal
Concentration:
1.03 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
Q14653
Gene Symbols:
IRF3
Immunogen:
A synthesized peptide derived from human Phospho-IRF3 (S386)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Western Blot
Clone:
4H10
Conjugate:
Unconjugated
Gene:
IRF3
Gene Alias:
C920001K05Rik, IIAE7, Interferon regulatory factor 3, IRF3, IRF-3, IRF3 (phospho S386), IRF3 (pS386), IRF3 (pSer386), IRF3 phospho, IRF3 phospho S386, IRF3 phospho Ser386, phospho IRF3
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
3661
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Antigen: Phospho-c-Jun (Ser63)
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P05412
Gene Symbols: JUN
Immunogen: A synthesized peptide derived from human Phospho-JUN (S63)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 4A11
Conjugate: Unconjugated
Gene: JUN
Gene Alias: Activator protein 1, AH119, AP1, AP-1, Avian sarcoma virus 17 (v-jun) oncogene homolog, cjun, c-Jun, c-jun transcription factor, enhancer-binding protein AP1, I79_009953, immediate early, JUN, Jun A, Jun activation domain binding protein, Jun oncogene, jun proto-oncogene, Jun proto-oncogene, AP-1 transcription factor subunit, Junc, JUND, p39, proto-oncogene c-Jun, Rjg-9, transcription factor, transcription factor AP-1, V-jun avian sarcoma virus 17 oncogene homolog, v-jun sarcoma virus 17 oncogene homolog
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 3725
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Antigen:
Phospho-c-Jun (Ser63)
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P05412
Gene Symbols:
JUN
Immunogen:
A synthesized peptide derived from human Phospho-JUN (S63)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
4A11
Conjugate:
Unconjugated
Gene:
JUN
Gene Alias:
Activator protein 1, AH119, AP1, AP-1, Avian sarcoma virus 17 (v-jun) oncogene homolog, cjun, c-Jun, c-jun transcription factor, enhancer-binding protein AP1, I79_009953, immediate early, JUN, Jun A, Jun activation domain binding protein, Jun oncogene, jun proto-oncogene, Jun proto-oncogene, AP-1 transcription factor subunit, Junc, JUND, p39, proto-oncogene c-Jun, Rjg-9, transcription factor, transcription factor AP-1, V-jun avian sarcoma virus 17 oncogene homolog, v-jun sarcoma virus 17 oncogene homolog
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
3725
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Antigen: Phospho-LAT (Tyr191)
Classification: Recombinant Monoclonal
Concentration: 2.35 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: O43561
Gene Symbols: LAT
Immunogen: A synthesized peptide derived from human Phospho-LAT (Y191)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Western Blot
Clone: 2E4
Conjugate: Unconjugated
Gene: LAT
Gene Alias: 36 kDa phospho-tyrosine adapter protein, 36 kDa phospho-tyrosine adaptor protein, Lat, LAT1, linker for activation of T cells, linker for activation of T cells, transmembrane adaptor, linker for activation of T-cells, linker for activation of T-cells family member 1, linker protein, p36-38, pp36
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 27040
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Antigen:
Phospho-LAT (Tyr191)
Classification:
Recombinant Monoclonal
Concentration:
2.35 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
O43561
Gene Symbols:
LAT
Immunogen:
A synthesized peptide derived from human Phospho-LAT (Y191)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Western Blot
Clone:
2E4
Conjugate:
Unconjugated
Gene:
LAT
Gene Alias:
36 kDa phospho-tyrosine adapter protein, 36 kDa phospho-tyrosine adaptor protein, Lat, LAT1, linker for activation of T cells, linker for activation of T cells, transmembrane adaptor, linker for activation of T-cells, linker for activation of T-cells family member 1, linker protein, p36-38, pp36
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
27040
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Antigen: Phospho-MEK1 (Thr292)
Classification: Recombinant Monoclonal
Concentration: 1.15 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: Q02750
Gene Symbols: Map2k1
Immunogen: A synthesized peptide derived from human Phospho-MAP2K1 (T292)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Western Blot
Clone: 4E7
Conjugate: Unconjugated
Gene: Map2k1
Gene Alias: CFC3, dual specificity mitogen activated protein kinase kinase 1, dual specificity mitogen-activated protein kinase kinase 1, EC 2.7.12.2, ERK activator kinase 1, kinase MEK1, MAP kinase kinase 1, MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2), MAP kinase/Erk kinase 1, Map2k1, map2k1.L, MAPK/ERK kinase 1, MAPKK 1, MAPKK1, MEK 1, Mek1, MEK2, mek-2, MEKK1, mitogen activated protein kinase kinase 1, mitogen-activated protein kinase kinase 1, mitogen-activated protein kinase kinase 1 L homeolog, MKK (Thr292), MKK (Thr386), MKK1, MKK2, MP2K1, Prkmk1, PRKMK2, protein kinase, mitogen activated, kinase 1, p45, protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1), XELAEV_18018447mg
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 5604
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Antigen:
Phospho-MEK1 (Thr292)
Classification:
Recombinant Monoclonal
Concentration:
1.15 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
Q02750
Gene Symbols:
Map2k1
Immunogen:
A synthesized peptide derived from human Phospho-MAP2K1 (T292)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Western Blot
Clone:
4E7
Conjugate:
Unconjugated
Gene:
Map2k1
Gene Alias:
CFC3, dual specificity mitogen activated protein kinase kinase 1, dual specificity mitogen-activated protein kinase kinase 1, EC 2.7.12.2, ERK activator kinase 1, kinase MEK1, MAP kinase kinase 1, MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2), MAP kinase/Erk kinase 1, Map2k1, map2k1.L, MAPK/ERK kinase 1, MAPKK 1, MAPKK1, MEK 1, Mek1, MEK2, mek-2, MEKK1, mitogen activated protein kinase kinase 1, mitogen-activated protein kinase kinase 1, mitogen-activated protein kinase kinase 1 L homeolog, MKK (Thr292), MKK (Thr386), MKK1, MKK2, MP2K1, Prkmk1, PRKMK2, protein kinase, mitogen activated, kinase 1, p45, protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1), XELAEV_18018447mg
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
5604
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid