PIMA532348
IRF3 Recombinant Rabbit Monoclonal Antibody (SD2062), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532348-Each-of-1 | In Stock | ₹ 49,838.70 |
PIMA532348 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,838.70
GST (18%): ₹ 8,970.966
Total Price: ₹ 58,809.666
Antigen
IRF3
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P70671, Q14653
Gene Symbols
IRF3
Immunogen
Synthetic peptide within Human IRF3 aa 71-120
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
SD2062
Conjugate
Unconjugated
Gene
IRF3
Gene Alias
C920001K05Rik, IIAE7, Interferon regulatory factor 3, IRF3, IRF-3, IRF3 (phospho S386), IRF3 (pS386), IRF3 (pSer386), IRF3 phospho, IRF3 phospho S386, IRF3 phospho Ser386, phospho IRF3
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
292892, 3661, 54131
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- IFR3 (interferon regulatory factor 3) is a key transcriptional regulator of type I interferon (IFN)-dependent immune responses
- It plays a critical role in the innate immune response against DNA and RNA viruses
- IFR3 regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters
- It acts as a more potent activator of the IFN-beta gene than the IFN-alpha gene and plays a critical role in both the early and late phases of the IFNA/B gene induction
- IFR3 is found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA, or toll-like receptor signaling
- It is phosphorylated by IKBKE and TBK1 kinases
- This induces a conformational change, leading to its dimerization and nuclear localization and association with CREB binding protein to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of the type I IFN and ISG genes
- Mutations in the gene can result in encephalopathy, acute, infection-induced, herpes-specific 7.
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Antigen: IRF3
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P70671, Q14653
Gene Symbols: IRF3
Immunogen: Synthetic peptide within Human IRF3 aa 71-120
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SD2062
Conjugate: Unconjugated
Gene: IRF3
Gene Alias: C920001K05Rik, IIAE7, Interferon regulatory factor 3, IRF3, IRF-3, IRF3 (phospho S386), IRF3 (pS386), IRF3 (pSer386), IRF3 phospho, IRF3 phospho S386, IRF3 phospho Ser386, phospho IRF3
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 292892, 3661, 54131
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
IRF3
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P70671, Q14653
Gene Symbols:
IRF3
Immunogen:
Synthetic peptide within Human IRF3 aa 71-120
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SD2062
Conjugate:
Unconjugated
Gene:
IRF3
Gene Alias:
C920001K05Rik, IIAE7, Interferon regulatory factor 3, IRF3, IRF-3, IRF3 (phospho S386), IRF3 (pS386), IRF3 (pSer386), IRF3 phospho, IRF3 phospho S386, IRF3 phospho Ser386, phospho IRF3
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
292892, 3661, 54131
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: RelB
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: Q01201
Gene Symbols: RELB
Immunogen: Synthetic peptide within Human RelB aa 1-50
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SD07-39
Conjugate: Unconjugated
Gene: RELB
Gene Alias: avian reticuloendotheliosis viral (v-rel) oncogene related B, IREL, I-REL, OTTHUMP00000221313, rel b, RELB, REL-B, RELB proto-oncogene, NF-kB subunit, shep, transcription factor RelB, v-rel avian reticuloendotheliosis viral oncogene homolog B, v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3), v-rel reticuloen, v-rel reticuloendotheliosis viral oncogene homolog B, v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5971
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
RelB
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
Q01201
Gene Symbols:
RELB
Immunogen:
Synthetic peptide within Human RelB aa 1-50
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SD07-39
Conjugate:
Unconjugated
Gene:
RELB
Gene Alias:
avian reticuloendotheliosis viral (v-rel) oncogene related B, IREL, I-REL, OTTHUMP00000221313, rel b, RELB, REL-B, RELB proto-oncogene, NF-kB subunit, shep, transcription factor RelB, v-rel avian reticuloendotheliosis viral oncogene homolog B, v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3), v-rel reticuloen, v-rel reticuloendotheliosis viral oncogene homolog B, v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5971
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Histone 1F0
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P07305, P10922, P43278
Gene Symbols: H1-0, H1F0
Immunogen: Synthetic peptide within Human Histone H10 aa 1-50
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SD206-04
Conjugate: Unconjugated
Gene: H1-0
Gene Alias: D130017D06Rik, H1 histone family member 0, H1 histone family, member 0, H1(0), H1.0, H1(0), H1-0, H10, H1-0 histone, H1f0, H1fv, histone H1', Histone H1(0), histone H1.0, Histone H1.0, N-terminally processed, Histone H1-0, MyD196
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 14958, 24437, 3005
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Histone 1F0
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P07305, P10922, P43278
Gene Symbols:
H1-0, H1F0
Immunogen:
Synthetic peptide within Human Histone H10 aa 1-50
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SD206-04
Conjugate:
Unconjugated
Gene:
H1-0
Gene Alias:
D130017D06Rik, H1 histone family member 0, H1 histone family, member 0, H1(0), H1.0, H1(0), H1-0, H10, H1-0 histone, H1f0, H1fv, histone H1', Histone H1(0), histone H1.0, Histone H1.0, N-terminally processed, Histone H1-0, MyD196
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
14958, 24437, 3005
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: PDPK1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: O15530, O55173, Q9Z2A0
Gene Symbols: Pdpk1
Immunogen: Synthetic peptide within Human PDPK1 aa 1-50
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SD204-9
Conjugate: Unconjugated
Gene: Pdpk1
Gene Alias: 3-phosphoinositide dependent protein kinase 1, 3-phosphoinositide dependent protein kinase-1, 3-phosphoinositide-dependent protein kinase 1, 3-phosphoinositide-dependent protein kinase 2 pseudogene, HGNC:8809, hPDK1, isoenzyme 1, kinase isoenzyme 1, lipoamide, mPDK1, OTTHUMP00000174525, OTTHUMP00000205076, PDK1, PDPK1, PDPK2, PDPK2P, Pkb kinase, PkB kinase like gene 1, PkB-like 1, PRO0461, Protein kinase B kinase
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 18607, 5170, 81745
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
PDPK1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
O15530, O55173, Q9Z2A0
Gene Symbols:
Pdpk1
Immunogen:
Synthetic peptide within Human PDPK1 aa 1-50
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SD204-9
Conjugate:
Unconjugated
Gene:
Pdpk1
Gene Alias:
3-phosphoinositide dependent protein kinase 1, 3-phosphoinositide dependent protein kinase-1, 3-phosphoinositide-dependent protein kinase 1, 3-phosphoinositide-dependent protein kinase 2 pseudogene, HGNC:8809, hPDK1, isoenzyme 1, kinase isoenzyme 1, lipoamide, mPDK1, OTTHUMP00000174525, OTTHUMP00000205076, PDK1, PDPK1, PDPK2, PDPK2P, Pkb kinase, PkB kinase like gene 1, PkB-like 1, PRO0461, Protein kinase B kinase
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
18607, 5170, 81745
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid