PIMA533182

Phospho-Tau (Ser396) Recombinant Rabbit Monoclonal Antibody (1G3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA533182-Each-of-1 In Stock ₹ 48,640.86

PIMA533182 - Each of 1

₹ 48,640.86

In Stock

Quantity

1

Base Price: ₹ 48,640.86

GST (18%): ₹ 8,755.355

Total Price: ₹ 57,396.215

Antigen

Phospho-Tau (Ser396)

Classification

Recombinant Monoclonal

Concentration

0.72 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

P10636, P10637, P19332

Gene Symbols

MAPT

Immunogen

A synthesized peptide derived from human Phospho-MAPT (S396)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

ELISA, Western Blot

Clone

1G3

Conjugate

Unconjugated

Gene

MAPT

Gene Alias

AI413597, AW045860, DDPAC, FLJ31424, FTDP17, FTDP-17, G protein beta1/gamma2 subunit-interacting factor 1, map tau, Mapt, MAPTL, MGC138549, microtubule associated protein tau, microtubule-associated protein tau, microtubule-associated protein tau, isoform 4, microtubules, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, neurofibrillary tangles, Neuronal Marker, paired helical filament-tau, PHFtau, PHF-tau, PPND, PPP1R103, protein phosphatase 1, regulatory subunit 103, pTau, RNPTAU, Tau, Tau microtubule-associated protein, tau protein, Tau-4, Tau5, Unknown (protein for MGC:134287)

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

17762, 29477, 4137

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

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Description

  • Tau is a neuronal microtubule-associated protein found predominantly on axons
  • The function of Tau is to promote tubulin polymerization and stabilize microtubules
  • The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both
  • Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome
  • The short isoforms allow plasticity of the cytoskeleton while the longer isoforms may preferentially play a role in its stabilization
  • In its hyper-phosphorylated form, Tau is the major component of paired helical filaments (PHF), the building block of neurofibrillary lesions in Alzheimer's diseases (AD) brain
  • Hyper-phosphorylation impairs the microtubule binding function of Tau, resulting in the destabilization of microtubules in AD brains, μgtimately leading to the degeneration of the affected neurons
  • Numerous serine/threonine kinases phosphorylate Tau, including GSK-3beta, protein kinase A (PKA), cyclin-dependent kinase 5 (cdk5) and casein kinase II
  • Hyper-phosphorylated Tau is found in neurofibrillary lesions in a range and other central nervous system disorders such as Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

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Img

Thermo Scientific

PIMA533182

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Antigen:
Phospho-Tau (Ser396)

Classification:
Recombinant Monoclonal

Concentration:
0.72 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P10636, P10637, P19332

Gene Symbols:
MAPT

Immunogen:
A synthesized peptide derived from human Phospho-MAPT (S396)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Western Blot

Clone:
1G3

Conjugate:
Unconjugated

Gene:
MAPT

Gene Alias:
AI413597, AW045860, DDPAC, FLJ31424, FTDP17, FTDP-17, G protein beta1/gamma2 subunit-interacting factor 1, map tau, Mapt, MAPTL, MGC138549, microtubule associated protein tau, microtubule-associated protein tau, microtubule-associated protein tau, isoform 4, microtubules, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, neurofibrillary tangles, Neuronal Marker, paired helical filament-tau, PHFtau, PHF-tau, PPND, PPP1R103, protein phosphatase 1, regulatory subunit 103, pTau, RNPTAU, Tau, Tau microtubule-associated protein, tau protein, Tau-4, Tau5, Unknown (protein for MGC:134287)

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
17762, 29477, 4137

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Img

Thermo Scientific

PIMA533183

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Antigen:
Phospho-c-Myc (Ser62)

Classification:
Recombinant Monoclonal

Concentration:
1.4 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P01106

Gene Symbols:
MYC

Immunogen:
A synthesized peptide derived from human Phospho-MYC (S62)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
2A10

Conjugate:
Unconjugated

Gene:
MYC

Gene Alias:
AU016757, Avian myelocytomatosis viral (v-myc) oncogene homolog, avian myelocytomatosis viral oncogene homolog, bHLHe39, c Myc, class E basic helix-loop-helix protein 39, cmyc, c-Myc, c-myc epitope tag, c-myc proto-oncogene, mMyc, MRTL, Myc, Myc protein, Myc proto-oncogene protein, MYC proto-oncogene, bHLH transcription factor, Myc2, MYCC, myc-related translation/localization regulatory factor, myelocytomatosis oncogene, myelocytomatosis viral oncogene homolog, Niard, Nird, Proto-oncogene c-Myc, RNCMYC, Transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene-like protein

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
4609

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Img

Thermo Scientific

PIMA533185

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Antigen:
Phospho-PAK1/2/3 (Ser139, Ser141, Ser144)

Classification:
Recombinant Monoclonal

Concentration:
0.85 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
O75914, Q13153, Q13177

Gene Symbols:
Pak1, PAK2, PAK3

Immunogen:
A synthesized peptide derived from human Phospho-PAK1/PAK2/PAK3 (S144+S141+S139)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Clone:
3H12

Conjugate:
Unconjugated

Gene:
PAK3

Gene Alias:
5330420P17Rik, A130002K10Rik, activated protein kinase alpha, ADRB2, adriamycin resistance-associated, AI836325, Alpha-PAK, ARA, AW045634, Beta-PAK, bPAK, CDC42/RAC effector kinase PAK-A, CDC42/RAC effector kinase PAK-B, CDKN1A, C-t-PAK2, D16Ertd269e, EC 2.7.11.1, gamma pak, gamma-PAK, hPAK3, kinase PAK1, mKIAA4182, MRX30, MRX47, oligophrenin-3, OPHN3, p21 (CDKN1A)-activated kinase 1, p21 (CDKN1A)-activated kinase 2, p21 (CDKN1A)-activated kinase 3, p21 (RAC1) activated kinase 1, p21 (RAC1) activated kinase 2, p21 (RAC1) activated kinase 3, p21 protein (Cdc42/Rac)-activated kinase 1, p21 protein (Cdc42/Rac)-activated kinase 2, p21 protein (Cdc42/Rac)-activated kinase 3, p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast), p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related), p21/Cdc42/Rac1-activated kinase 3 (yeast Ste20-related), p21-activated kinase 1, p21-activated kinase 2, p21-activated kinase 3, p27, p34, p58, p65-PAK, p68-PAK, PAK 1, PAK alpha, PAK beta, PAK gamma, Pak1, PAK-1, Pak2, PAK-2, PAK-2p27, PAK-2p34, PAK3, PAK-3, PAK3beta, PAK65, Pak65alpha, Pak65beta, Paka, PAKalpha, Pakb, PAKgamma, Protein kinase MUK2, S6/H4 kinase, Serine/threonine-protein kinase PAK 1, serine/threonine-protein kinase PAK 2, Serine/threonine-protein kinase PAK 3, STE20 homolog, yeast, Stk4

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5058, 5062, 5063

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Img

Thermo Scientific

PIMA533187

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Antigen:
Phospho-RNA pol II CTD (Ser2)

Classification:
Recombinant Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P24928

Gene Symbols:
POLR2A

Immunogen:
A synthesized peptide derived from human Phospho-POLR2A (S2)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
2G1

Conjugate:
Unconjugated

Gene:
POLR2A

Gene Alias:
220kDa, AW321876, DNA polymerase alpha 1 catalytic subunit, DNA polymerase alpha 1, 180 kDa, DNA polymerase alpha 1, catalytic subunit, DNA polymerase alpha catalytic subunit, DNA polymerase alpha catalytic subunit p180, DNA polymerase alpha p180 subunit, DNA polymerase alpha subunit I, DNA polymerase epsilon catalytic subunit, DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A, DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase III largest subunit, DUN2, EC 2.7.7.6, G7a/Bat6Hom, hRPB220, hsRPB1, I79_002751, I79_016081, MGC75453, N0825, NSX, p180, Pol II S2p, POL2, Pola, Pola1, POLR2, POLR2A, POLRA, polymerase (DNA directed), alpha 1, polymerase (DNA directed), alpha 1, catalytic subunit, polymerase (DNA) alpha 1, catalytic subunit, polymerase (DNA-directed), alpha (70kD), Polymerase (RNA II (DNA directed), large polypeptide, polymerase (RNA) II (DNA directed) polypeptide A, polymerase (RNA) II (DNA directed) polypeptide A, 220kDa, polymerase (RNA) II subunit A, POLYMERASE II, polymerase, alpha 1, RNA, RNA POL2, RNA polymerase II 1, RNA polymerase II carboxy-terminal domain, RNA polymerase II C-terminal domain, RNA polymerase II largest subunit, RNA polymerase II subunit A, RNA polymerase II subunit B1, RNA-directed RNA polymerase II subunit RPB1, RP02, Rpb1, RPB220, RPBh1, Rpii215, RpIILS, RPO2, RPO21, Rpo2-1, RPOL2, SUA8, YNL262W

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5430

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid