PIMA533202
Phospho-p53 (Thr55) Recombinant Rabbit Monoclonal Antibody (3C3), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533202-Each-of-1 | In Stock | ₹ 48,640.86 |
PIMA533202 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,640.86
GST (18%): ₹ 8,755.355
Total Price: ₹ 57,396.215
Antigen
Phospho-p53 (Thr55)
Classification
Recombinant Monoclonal
Concentration
2.5 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
P04637
Gene Symbols
Tp53
Immunogen
A synthesized peptide derived from human Phospho-TP53 (T55)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ELISA, Immunocytochemistry, Western Blot
Clone
3C3
Conjugate
Unconjugated
Gene
Tp53
Gene Alias
Antigen NY-CO-13, bbl, BCC7, bfy, bhy, cellular tumor antigen p53, Cys 51 Stop, EGK_08142, FLJ92943, HGNC11998, I79_002739, LFS1, Li-Fraumeni syndrome, mutant p53, mutant tumor protein 53, OTTMUSP00000006194, p44, p53, p53 cellular tumor antigen, p53 protein, p53 tumor suppressor, p53 tumor suppressor phosphoprotein, phosphoprotein p53, Tp53, tp53.L, transformation related protein 53, transformation-related protein 53, Trp248, Trp53, tumor protein 53, tumor protein p53, tumor protein p53 (Li-Fraumeni syndrome), tumor protein p53 L homeolog, tumor suppressor p53, tumor suppressor p53 phosphoprotein, tumor suppressor protein p53, tumor supressor p53, Tumour Protein p53, XELAEV_180196761mg, Xp53, Xrel3
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
7157
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Related Products
Description
- The tumor suppressor protein, p53, is a sequence specific transcription factor that is activated by cellular stress
- p53 mediates cell cycle arrest or apoptosis in response to DNA damage or starvation for pyrimidine nucleotides
- p53 is up-regulated in response to stress signals and stimulated to activate transcription of specific genes, resulting in expression of p21waf1 and other proteins involved in G1 or G2/M arrest
- The structure of p53 comprises an N-terminal transactivation domain, a central DNA-binding domain, an oligomerisation domain, and a C-terminal regulatory domain
- There are various phosphorylation sites on p53, of which the phosphorylation at Ser15 is important for p53 activation and stabilization
- p53 has been characterized to play a role in blocking the proliferative action of damaged cells and act as an anticancer agent
- Phosphorylation of Ser392 in p53 has been shown to associate with the formation of human tumors
- In addition, p53 has also been linked to the effects of aging and oxidative stress and an increase in p53 has been linked to deficits in LTP (Long Term Potentiation) in learning and memory
- p53 is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy
- Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and cause the loss of tumor suppressor activity
- Alterations of the TP53 gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families such as Li-Fraumeni syndrome.
Compare Similar Items
Show Difference
Antigen: Phospho-p53 (Thr55)
Classification: Recombinant Monoclonal
Concentration: 2.5 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P04637
Gene Symbols: Tp53
Immunogen: A synthesized peptide derived from human Phospho-TP53 (T55)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Immunocytochemistry, Western Blot
Clone: 3C3
Conjugate: Unconjugated
Gene: Tp53
Gene Alias: Antigen NY-CO-13, bbl, BCC7, bfy, bhy, cellular tumor antigen p53, Cys 51 Stop, EGK_08142, FLJ92943, HGNC11998, I79_002739, LFS1, Li-Fraumeni syndrome, mutant p53, mutant tumor protein 53, OTTMUSP00000006194, p44, p53, p53 cellular tumor antigen, p53 protein, p53 tumor suppressor, p53 tumor suppressor phosphoprotein, phosphoprotein p53, Tp53, tp53.L, transformation related protein 53, transformation-related protein 53, Trp248, Trp53, tumor protein 53, tumor protein p53, tumor protein p53 (Li-Fraumeni syndrome), tumor protein p53 L homeolog, tumor suppressor p53, tumor suppressor p53 phosphoprotein, tumor suppressor protein p53, tumor supressor p53, Tumour Protein p53, XELAEV_180196761mg, Xp53, Xrel3
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 7157
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Antigen:
Phospho-p53 (Thr55)
Classification:
Recombinant Monoclonal
Concentration:
2.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P04637
Gene Symbols:
Tp53
Immunogen:
A synthesized peptide derived from human Phospho-TP53 (T55)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Immunocytochemistry, Western Blot
Clone:
3C3
Conjugate:
Unconjugated
Gene:
Tp53
Gene Alias:
Antigen NY-CO-13, bbl, BCC7, bfy, bhy, cellular tumor antigen p53, Cys 51 Stop, EGK_08142, FLJ92943, HGNC11998, I79_002739, LFS1, Li-Fraumeni syndrome, mutant p53, mutant tumor protein 53, OTTMUSP00000006194, p44, p53, p53 cellular tumor antigen, p53 protein, p53 tumor suppressor, p53 tumor suppressor phosphoprotein, phosphoprotein p53, Tp53, tp53.L, transformation related protein 53, transformation-related protein 53, Trp248, Trp53, tumor protein 53, tumor protein p53, tumor protein p53 (Li-Fraumeni syndrome), tumor protein p53 L homeolog, tumor suppressor p53, tumor suppressor p53 phosphoprotein, tumor suppressor protein p53, tumor supressor p53, Tumour Protein p53, XELAEV_180196761mg, Xp53, Xrel3
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
7157
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Antigen: TSPO
Classification: Recombinant Monoclonal
Concentration: 0.94 mg/mL
Formulation: PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P30536, P50637
Gene Symbols: Tspo
Immunogen: A synthesized peptide derived from human TSPO (50-169aa)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Immunohistochemistry (Paraffin)
Clone: 23G2
Conjugate: Unconjugated
Gene: Tspo
Gene Alias: Benzodiazepin receptor (peripheral), benzodiazepine peripheral binding site, benzodiazepine receptor, peripheral, BPBS, BZRP, DBI, IBP, isoquinoline-binding protein, MBR, mDRC, mitochondrial benzodiazepine receptor, OTTHUMP00000028891, PBR, PBS, peripheral-type benzodiazepine receptor, pk18, PKBS, PTBR, Ptbzr, PTBZR02, RATPTBZR02, translocator protein, translocator protein (18kDa), TSPO, Tspo1
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 12257, 706
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Antigen:
TSPO
Classification:
Recombinant Monoclonal
Concentration:
0.94 mg/mL
Formulation:
PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P30536, P50637
Gene Symbols:
Tspo
Immunogen:
A synthesized peptide derived from human TSPO (50-169aa)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Immunohistochemistry (Paraffin)
Clone:
23G2
Conjugate:
Unconjugated
Gene:
Tspo
Gene Alias:
Benzodiazepin receptor (peripheral), benzodiazepine peripheral binding site, benzodiazepine receptor, peripheral, BPBS, BZRP, DBI, IBP, isoquinoline-binding protein, MBR, mDRC, mitochondrial benzodiazepine receptor, OTTHUMP00000028891, PBR, PBS, peripheral-type benzodiazepine receptor, pk18, PKBS, PTBR, Ptbzr, PTBZR02, RATPTBZR02, translocator protein, translocator protein (18kDa), TSPO, Tspo1
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
12257, 706
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Antigen: VDAC
Classification: Recombinant Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P21796, Q60932, Q9Z2L0
Gene Symbols: VDAC1
Immunogen: A synthesized peptide derived from human VDAC1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 3A1
Conjugate: Unconjugated
Gene: VDAC1
Gene Alias: AL033343, BR1-VDAC, Brain-derived voltage-dependent anion channel 1, hVDAC1, MGC111064, Mitochondrial outer membrane protein porin 1, Mitochondrial Porin, mVDAC1, mVDAC5, N2441, OMP2, Outer mitochondrial membrane protein porin 1, plasmalemmal porin, POR1, PORIN, Porin 31HL, porin 31HM, porin POR1, PORIN-31-HL, rVDAC1, VD, VDAC, VDAC1, VDAC-1, Vdac5, VDAC-5, voltage dependent anion channel 1, voltage-dependent anion channel 1, voltage-dependent anion-selective channel protein 1, Voltage-dependent anion-selective channel protein 5, YNL055C, YNL2441C
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 22333, 7416, 83529
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Antigen:
VDAC
Classification:
Recombinant Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P21796, Q60932, Q9Z2L0
Gene Symbols:
VDAC1
Immunogen:
A synthesized peptide derived from human VDAC1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
3A1
Conjugate:
Unconjugated
Gene:
VDAC1
Gene Alias:
AL033343, BR1-VDAC, Brain-derived voltage-dependent anion channel 1, hVDAC1, MGC111064, Mitochondrial outer membrane protein porin 1, Mitochondrial Porin, mVDAC1, mVDAC5, N2441, OMP2, Outer mitochondrial membrane protein porin 1, plasmalemmal porin, POR1, PORIN, Porin 31HL, porin 31HM, porin POR1, PORIN-31-HL, rVDAC1, VD, VDAC, VDAC1, VDAC-1, Vdac5, VDAC-5, voltage dependent anion channel 1, voltage-dependent anion channel 1, voltage-dependent anion-selective channel protein 1, Voltage-dependent anion-selective channel protein 5, YNL055C, YNL2441C
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
22333, 7416, 83529
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Antigen: Phospho-YAP1 (Ser127)
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P46937
Gene Symbols: YAP1
Immunogen: A synthesized peptide derived from human Phospho-YAP1 (S127)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 3F3
Conjugate: Unconjugated
Gene: YAP1
Gene Alias: 65 kDa Yes-associated protein, AI325207, cb194, CH211-181P1.5-001, COB1, Protein yorkie homolog, sb:cb194, si:ch211-181p1.5, si:dkey-3b8.3, transcriptional coactivator YAP1, wu:fc18c04, yap, Yap1, YAP2, Yap65, Yes associated protein 1, Yes1 associated transcriptional regulator, yes-associated protein 1, yes-associated protein 2, yes-associated protein YAP65 homolog, yes-associated protein, 65 kDa, Yki, Yorkie, yorkie homolog, zgc:158380, zYAP
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 10413
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Antigen:
Phospho-YAP1 (Ser127)
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P46937
Gene Symbols:
YAP1
Immunogen:
A synthesized peptide derived from human Phospho-YAP1 (S127)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
3F3
Conjugate:
Unconjugated
Gene:
YAP1
Gene Alias:
65 kDa Yes-associated protein, AI325207, cb194, CH211-181P1.5-001, COB1, Protein yorkie homolog, sb:cb194, si:ch211-181p1.5, si:dkey-3b8.3, transcriptional coactivator YAP1, wu:fc18c04, yap, Yap1, YAP2, Yap65, Yes associated protein 1, Yes1 associated transcriptional regulator, yes-associated protein 1, yes-associated protein 2, yes-associated protein YAP65 homolog, yes-associated protein, 65 kDa, Yki, Yorkie, yorkie homolog, zgc:158380, zYAP
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
10413
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid