PIMA535159
MERTK Recombinant Rabbit Monoclonal Antibody (ARC0229), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA535159-Each-of-1 | In Stock | ₹ 45,646.26 |
PIMA535159 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,646.26
GST (18%): ₹ 8,216.327
Total Price: ₹ 53,862.587
Antigen
MERTK
Classification
Monoclonal
Concentration
0.75 mg/mL
Formulation
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q12866
Gene Symbols
Mertk
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MERTK (Q12866)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Clone
ARC0229
Conjugate
Unconjugated
Gene
Mertk
Gene Alias
c-Eyk; c-mer; c-mer proto-oncogene tyrosine kinase; Eyk; MER; MER proto-oncogene, tyrosine kinase; MER receptor tyrosine kinase; MERTK; MGC133349; nmf12; Nyk; Proto-oncogene c-Mer; proto-oncogene tyrosine-protein kinase MER; rdy; receptor tyrosine kinase MerTK; Receptor tyrosine tinase gene probably the gene for Rdy; retinal dystrophy; RP38; sMER; sMERTK; soluble MER; soluble MERTK; STK kinase; Tyro 12; Tyro12; Tyrosine-protein kinase Mer
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10461
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Immunogen sequence: MGPAPLPLLL GLFLPALWRR AITEAREEAK PYPLFPGPFP GSLQTDHTPL LSLPHASGYQ PALMFSPTQP GRPHTGNVAI PQVTSVESKP LPPLAFKHTV MERTK (cMER) is a tyrosine kinase proto-oncogene and is involved in the retinal pigment epithelium (RPE) phagocytosis pathway, which is implicated in human retinal disease
- Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis)
- Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules
- Following activation by ligand, interacts with GRB2 or PLCG2 and induces phosphorylation of MAPK1, MAPK2, FAK/PTK2 or RAC1
- MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment
- Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis
- Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.
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Antigen: MERTK
Classification: Monoclonal
Concentration: 0.75 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q12866
Gene Symbols: Mertk
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MERTK (Q12866)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: ARC0229
Conjugate: Unconjugated
Gene: Mertk
Gene Alias: c-Eyk; c-mer; c-mer proto-oncogene tyrosine kinase; Eyk; MER; MER proto-oncogene, tyrosine kinase; MER receptor tyrosine kinase; MERTK; MGC133349; nmf12; Nyk; Proto-oncogene c-Mer; proto-oncogene tyrosine-protein kinase MER; rdy; receptor tyrosine kinase MerTK; Receptor tyrosine tinase gene probably the gene for Rdy; retinal dystrophy; RP38; sMER; sMERTK; soluble MER; soluble MERTK; STK kinase; Tyro 12; Tyro12; Tyrosine-protein kinase Mer
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10461
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
MERTK
Classification:
Monoclonal
Concentration:
0.75 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q12866
Gene Symbols:
Mertk
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MERTK (Q12866)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
ARC0229
Conjugate:
Unconjugated
Gene:
Mertk
Gene Alias:
c-Eyk; c-mer; c-mer proto-oncogene tyrosine kinase; Eyk; MER; MER proto-oncogene, tyrosine kinase; MER receptor tyrosine kinase; MERTK; MGC133349; nmf12; Nyk; Proto-oncogene c-Mer; proto-oncogene tyrosine-protein kinase MER; rdy; receptor tyrosine kinase MerTK; Receptor tyrosine tinase gene probably the gene for Rdy; retinal dystrophy; RP38; sMER; sMERTK; soluble MER; soluble MERTK; STK kinase; Tyro 12; Tyro12; Tyrosine-protein kinase Mer
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10461
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: LC3A
Classification: Monoclonal
Concentration: 0.39 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q9H492
Gene Symbols: MAP1LC3A
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAP1LC3A (Q9H492)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunoprecipitation, Western Blot
Clone: 7F5R1
Conjugate: Unconjugated
Gene: MAP1LC3A
Gene Alias: 1010001H21Rik; 4922501H04Rik; ATG8E; Autophagy-related protein LC3 A; autophagy-related ubiquitin-like modifier LC3 A; LC3; LC3a; MAP1 light chain 3-like protein 1; MAP1A/1B light chain 3 A; MAP1A/MAP1B LC3 A; MAP1A/MAP1B light chain 3 A; MAP1ALC3; MAP1BLC3; map1lc3a; microtubule associated protein 1 light chain 3 alpha; Microtubule-asso; microtubule-associated protein 1 light chain 3 alpha; microtubule-associated protein 1-light chain 3A; microtubule-associated proteins 1A/1B light chain 3; microtubule-associated proteins 1A/1B light chain 3A; MLP3A; RP11-346K17.1; similar to microtubule-associated protein 1 light chain 3 alpha; zgc:77094
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 84557
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
LC3A
Classification:
Monoclonal
Concentration:
0.39 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q9H492
Gene Symbols:
MAP1LC3A
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAP1LC3A (Q9H492)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunoprecipitation, Western Blot
Clone:
7F5R1
Conjugate:
Unconjugated
Gene:
MAP1LC3A
Gene Alias:
1010001H21Rik; 4922501H04Rik; ATG8E; Autophagy-related protein LC3 A; autophagy-related ubiquitin-like modifier LC3 A; LC3; LC3a; MAP1 light chain 3-like protein 1; MAP1A/1B light chain 3 A; MAP1A/MAP1B LC3 A; MAP1A/MAP1B light chain 3 A; MAP1ALC3; MAP1BLC3; map1lc3a; microtubule associated protein 1 light chain 3 alpha; Microtubule-asso; microtubule-associated protein 1 light chain 3 alpha; microtubule-associated protein 1-light chain 3A; microtubule-associated proteins 1A/1B light chain 3; microtubule-associated proteins 1A/1B light chain 3A; MLP3A; RP11-346K17.1; similar to microtubule-associated protein 1 light chain 3 alpha; zgc:77094
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
84557
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: ACSS2
Classification: Monoclonal
Concentration: 2 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q9NR19, Q9QXG4
Gene Symbols: Acss2
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human ACSS2 (Q9NR19)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: ARC0690
Conjugate: Unconjugated
Gene: Acss2
Gene Alias: 1110017C11Rik; ACAS; Acas1; Acas2; ACECS; AceCS1; acetate thiokinase; acetate-CoA ligase; acetate--CoA ligase; Acetyl-CoA synthetase; Acetyl-CoA synthetase 1; acetyl-Coenzyme A synthetase 1 (AMP forming); acetyl-Coenzyme A synthetase 2 (ADP forming); acetyl-Coenzyme A synthetase 2 (AMP forming); acetyl-coenzyme A synthetase, cytoplasmic; ACS; Acs1; ACSA; ACSS2; Acyl-activating enzyme; acyl-CoA synthetase short-chain family member 2; cytoplasmic acetyl-coenzyme A synthetase; dJ1161H23.1; Propionate--CoA ligase
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 311569, 55902, 60525
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
ACSS2
Classification:
Monoclonal
Concentration:
2 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q9NR19, Q9QXG4
Gene Symbols:
Acss2
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human ACSS2 (Q9NR19)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
ARC0690
Conjugate:
Unconjugated
Gene:
Acss2
Gene Alias:
1110017C11Rik; ACAS; Acas1; Acas2; ACECS; AceCS1; acetate thiokinase; acetate-CoA ligase; acetate--CoA ligase; Acetyl-CoA synthetase; Acetyl-CoA synthetase 1; acetyl-Coenzyme A synthetase 1 (AMP forming); acetyl-Coenzyme A synthetase 2 (ADP forming); acetyl-Coenzyme A synthetase 2 (AMP forming); acetyl-coenzyme A synthetase, cytoplasmic; ACS; Acs1; ACSA; ACSS2; Acyl-activating enzyme; acyl-CoA synthetase short-chain family member 2; cytoplasmic acetyl-coenzyme A synthetase; dJ1161H23.1; Propionate--CoA ligase
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
311569, 55902, 60525
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: TOP1
Classification: Monoclonal
Concentration: 0.32 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P11387, Q04750
Gene Symbols: Top1
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DNA topoisomerase I (TOP1) (P11387)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: ARC0708
Conjugate: Unconjugated
Gene: Top1
Gene Alias: Ab2-086; AI467334; D130064I21Rik; DNA topoisomerase 1; DNA topoisomerase I; RP3-511B24.2; TOP1; Top-1; TOPI; topoisomerase (DNA) I; type I DNA topoisomerase
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 21969, 7150
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
TOP1
Classification:
Monoclonal
Concentration:
0.32 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P11387, Q04750
Gene Symbols:
Top1
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DNA topoisomerase I (TOP1) (P11387)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
ARC0708
Conjugate:
Unconjugated
Gene:
Top1
Gene Alias:
Ab2-086; AI467334; D130064I21Rik; DNA topoisomerase 1; DNA topoisomerase I; RP3-511B24.2; TOP1; Top-1; TOPI; topoisomerase (DNA) I; type I DNA topoisomerase
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
21969, 7150
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid