PIMA544594
MERTK Recombinant Rabbit Monoclonal Antibody (RM469), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA544594-Each-of-1 | In Stock | ₹ 38,416.44 |
PIMA544594 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,416.44
GST (18%): ₹ 6,914.959
Total Price: ₹ 45,331.399
Antigen
MERTK
Classification
Recombinant Monoclonal
Concentration
50 μg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.
Q60805
Gene Symbols
Mertk
Immunogen
Recombinant protein of MerTK extracellular domain. Sequence is proprietary.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
RM469
Conjugate
Unconjugated
Gene
Mertk
Gene Alias
c-Eyk, c-mer, c-mer proto-oncogene tyrosine kinase, Eyk, MER, MER proto-oncogene, tyrosine kinase, MER receptor tyrosine kinase, MERTK, MGC133349, nmf12, Nyk, Proto-oncogene c-Mer, proto-oncogene tyrosine-protein kinase MER, rdy, receptor tyrosine kinase MerTK, Receptor tyrosine tinase gene probably the gene for Rdy, retinal dystrophy, RP38, sMER, sMERTK, soluble MER, soluble MERTK, STK kinase, Tyro 12, Tyro12, Tyrosine-protein kinase Mer
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
17289
Content And Storage
-20°C
Isotype
IgG
Related Products
Description
- MERTK (cMER) is a tyrosine kinase proto-oncogene and is involved in the retinal pigment epithelium (RPE) phagocytosis pathway, which is implicated in human retinal disease
- Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis)
- Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules
- Following activation by ligand, interacts with GRB2 or PLCG2 and induces phosphorylation of MAPK1, MAPK2, FAK/PTK2 or RAC1
- MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment
- Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis
- Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.
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Antigen: MERTK
Classification: Recombinant Monoclonal
Concentration: 50 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: Q60805
Gene Symbols: Mertk
Immunogen: Recombinant protein of MerTK extracellular domain. Sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: RM469
Conjugate: Unconjugated
Gene: Mertk
Gene Alias: c-Eyk, c-mer, c-mer proto-oncogene tyrosine kinase, Eyk, MER, MER proto-oncogene, tyrosine kinase, MER receptor tyrosine kinase, MERTK, MGC133349, nmf12, Nyk, Proto-oncogene c-Mer, proto-oncogene tyrosine-protein kinase MER, rdy, receptor tyrosine kinase MerTK, Receptor tyrosine tinase gene probably the gene for Rdy, retinal dystrophy, RP38, sMER, sMERTK, soluble MER, soluble MERTK, STK kinase, Tyro 12, Tyro12, Tyrosine-protein kinase Mer
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 17289
Content And Storage: -20°C
Isotype: IgG
Antigen:
MERTK
Classification:
Recombinant Monoclonal
Concentration:
50 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
Q60805
Gene Symbols:
Mertk
Immunogen:
Recombinant protein of MerTK extracellular domain. Sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
RM469
Conjugate:
Unconjugated
Gene:
Mertk
Gene Alias:
c-Eyk, c-mer, c-mer proto-oncogene tyrosine kinase, Eyk, MER, MER proto-oncogene, tyrosine kinase, MER receptor tyrosine kinase, MERTK, MGC133349, nmf12, Nyk, Proto-oncogene c-Mer, proto-oncogene tyrosine-protein kinase MER, rdy, receptor tyrosine kinase MerTK, Receptor tyrosine tinase gene probably the gene for Rdy, retinal dystrophy, RP38, sMER, sMERTK, soluble MER, soluble MERTK, STK kinase, Tyro 12, Tyro12, Tyrosine-protein kinase Mer
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
17289
Content And Storage:
-20°C
Isotype:
IgG
Antigen: AMACR
Classification: Recombinant Monoclonal
Concentration: 100 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: Q9UHK6
Gene Symbols: AMACR
Immunogen: A peptide corresponding to residues in human p504s/AMACR. The immunogen range is a synthetic peptide within amino acids 1-100 of human AMACR.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: RM349
Conjugate: Unconjugated
Gene: AMACR
Gene Alias: 2-arylpropionyl-CoA epimerase, 2-methylacyl-CoA racemase, Alpha-methylacyl-CoA racemase, alpha-methylacyl-Coenzyme A racemase, Amacr, AMACRD, amcr, CBAS4, Da1-8, Macr1, Marc1, OTTHUMP00000219978, OTTHUMP00000219979, RACE, RM
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 23600
Content And Storage: -20°C
Isotype: IgG
Antigen:
AMACR
Classification:
Recombinant Monoclonal
Concentration:
100 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
Q9UHK6
Gene Symbols:
AMACR
Immunogen:
A peptide corresponding to residues in human p504s/AMACR. The immunogen range is a synthetic peptide within amino acids 1-100 of human AMACR.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
RM349
Conjugate:
Unconjugated
Gene:
AMACR
Gene Alias:
2-arylpropionyl-CoA epimerase, 2-methylacyl-CoA racemase, Alpha-methylacyl-CoA racemase, alpha-methylacyl-Coenzyme A racemase, Amacr, AMACRD, amcr, CBAS4, Da1-8, Macr1, Marc1, OTTHUMP00000219978, OTTHUMP00000219979, RACE, RM
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
23600
Content And Storage:
-20°C
Isotype:
IgG
Antigen: NeuN
Classification: Recombinant Monoclonal
Concentration: 100 μg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: A6NFN3
Gene Symbols: RBFOX3
Immunogen: A peptide corresponding to the N-terminus of human NeuN (Fox3, RBFOX3).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: RM312
Conjugate: Unconjugated
Gene: RBFOX3
Gene Alias: D11Bwg0517e, FLJ56884, FLJ58356, fox 1 homolog (C. elegans) 3, fox1 homolog C, Fox-1 homolog C, FOX3, FOX-3, FOX3NeuN, hexaribonucleotide binding protein 3, hexaribonucleotide binding protein 3 (HRNBP3), Hexaribonucleotide-binding protein 3, Hrnbp3, NEUN, NeuN antigen, Neuna60, neuronal nuclear antigen A60, neuronal nuclei, Neuronal nuclei antigen, RBFOX3, RFOX3, RGD1560070, RNA binding fox-1 homolog 3, RNA binding protein, RNA binding protein fox-1 homolog 3, RNA binding protein, fox-1 homolog (C. elegans) 3, RNA binding protein, fox-1 homolog 3
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 146713
Content And Storage: -20°C
Isotype: IgG
Antigen:
NeuN
Classification:
Recombinant Monoclonal
Concentration:
100 μg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
A6NFN3
Gene Symbols:
RBFOX3
Immunogen:
A peptide corresponding to the N-terminus of human NeuN (Fox3, RBFOX3).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
RM312
Conjugate:
Unconjugated
Gene:
RBFOX3
Gene Alias:
D11Bwg0517e, FLJ56884, FLJ58356, fox 1 homolog (C. elegans) 3, fox1 homolog C, Fox-1 homolog C, FOX3, FOX-3, FOX3NeuN, hexaribonucleotide binding protein 3, hexaribonucleotide binding protein 3 (HRNBP3), Hexaribonucleotide-binding protein 3, Hrnbp3, NEUN, NeuN antigen, Neuna60, neuronal nuclear antigen A60, neuronal nuclei, Neuronal nuclei antigen, RBFOX3, RFOX3, RGD1560070, RNA binding fox-1 homolog 3, RNA binding protein, RNA binding protein fox-1 homolog 3, RNA binding protein, fox-1 homolog (C. elegans) 3, RNA binding protein, fox-1 homolog 3
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
146713
Content And Storage:
-20°C
Isotype:
IgG
Antigen: NSD1
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: Q96L73
Gene Symbols: NSD1
Immunogen: Recombinant protein within human NSD1 aa 1-200.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ChIP Assay, Immunocytochemistry
Clone: 1B1
Conjugate: Unconjugated
Gene: NSD1
Gene Alias: AI528500; Androgen receptor coactivator 267 kDa protein; androgen receptor-associated coregulator 267; androgen receptor-associated protein of 267 kDa; ARA267; H3-K36-HMTase; H4-K20-HMTase; Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific; KMT3B; Lysine N-methyltransferase 3B; NR-binding SET domain-containing protein; NSD1; nuclear receptor binding SET domain protein 1; nuclear receptor-binding SET domain-containing protein 1; nuclear receptor-binding SET-domain protein 1; SOTOS; SOTOS1; STO
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 64324
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG
Antigen:
NSD1
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
Q96L73
Gene Symbols:
NSD1
Immunogen:
Recombinant protein within human NSD1 aa 1-200.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ChIP Assay, Immunocytochemistry
Clone:
1B1
Conjugate:
Unconjugated
Gene:
NSD1
Gene Alias:
AI528500; Androgen receptor coactivator 267 kDa protein; androgen receptor-associated coregulator 267; androgen receptor-associated protein of 267 kDa; ARA267; H3-K36-HMTase; H4-K20-HMTase; Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific; KMT3B; Lysine N-methyltransferase 3B; NR-binding SET domain-containing protein; NSD1; nuclear receptor binding SET domain protein 1; nuclear receptor-binding SET domain-containing protein 1; nuclear receptor-binding SET-domain protein 1; SOTOS; SOTOS1; STO
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
64324
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG