PIMA535339

ATG5 Recombinant Rabbit Monoclonal Antibody (ARC0156), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA535339-Each-of-1 In Stock ₹ 45,646.26

PIMA535339 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

ATG5

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q3MQ06, Q99J83, Q9H1Y0

Gene Symbols

Atg5

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ATG5 (Q9H1Y0)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

ARC0156

Conjugate

Unconjugated

Gene

Atg5

Gene Alias

2010107M05Rik; 3110067M24Rik; APG 5; APG5; APG5 autophagy 5 like (APG5L); APG5 autophagy 5-like protein; APG5 autophagy 5-like protein, isoform 1; APG5L; APG5-LIKE; apoptosis-specific protein; Apoptosis-specific protein (ASP); ASP; atg5; Atg-5; ATG5 autophagy related 5 homolog; ATG5 autophagy related 5 homolog (S. cerevisiae); atg5.L; Atg5l; Atg5-PA; autophagy 5-like protein; autophagy protein 5; autophagy related 5; autophagy related 5 L homeolog; autophagy related 5-like protein; Autophagy-related 5; autophagy-specific gene 5; AW319544; C88337; CG1643; CG1643-PA; DmAtg5; Dmel\CG1643; Dmel_CG1643; hAPG5; hypothetical protein LOC532686; LD34980p; Paddy; XELAEV_18027227mg; zgc:100934

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11793, 365601, 9474

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Immunogen sequence: MTDDKDVLRD VWFGRIPTCF TLYQDEITER EAEPYYLLLP RVSYLTLVTD KVKKHFQKVM RQEDISEIWF EYEGTPLKWH YPIGLLFDLL ASSSALPWNI ATG5 (Autophagy Related 5) is an important element for autophagy and may play an important role in the apoptotic process
  • ATG5 is also involved in other cellular processes that include mitochondrial quality control after oxidative damage, negative regulation of the innate anti-viral immune response, lymphocyte development and proliferation, MHC II antigen presentation, and adipocyte differentiation
  • Following conjugation to ATG12, the conjugate participates in the formation of autophagosome
  • ATG5 contributes to autophagic cell death by interacting with Fas-associated protein with death domain (FADD)
  • The ATG5-ATG12 conjugate forms a cup-shaped isolation membrane that then detaches from the membrane immediately before or after autophagosome formation is completed
  • APG5 may play a role in the apoptotic process, possibly within the modified cytoskeleton
  • Further, APG5 expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity
  • The APG5-APG12 conjugate also associates with innate immune response proteins such as RIG-I and VISA (also known as IPS-1), inhibiting type I interferon production and permitting viral replication in host cells
  • Diseases associated with ATG5 dysfunction include spinocerebellar ataxia.

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Thermo Scientific

PIMA535339

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Antigen:
ATG5

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q3MQ06, Q99J83, Q9H1Y0

Gene Symbols:
Atg5

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ATG5 (Q9H1Y0)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
ARC0156

Conjugate:
Unconjugated

Gene:
Atg5

Gene Alias:
2010107M05Rik; 3110067M24Rik; APG 5; APG5; APG5 autophagy 5 like (APG5L); APG5 autophagy 5-like protein; APG5 autophagy 5-like protein, isoform 1; APG5L; APG5-LIKE; apoptosis-specific protein; Apoptosis-specific protein (ASP); ASP; atg5; Atg-5; ATG5 autophagy related 5 homolog; ATG5 autophagy related 5 homolog (S. cerevisiae); atg5.L; Atg5l; Atg5-PA; autophagy 5-like protein; autophagy protein 5; autophagy related 5; autophagy related 5 L homeolog; autophagy related 5-like protein; Autophagy-related 5; autophagy-specific gene 5; AW319544; C88337; CG1643; CG1643-PA; DmAtg5; Dmel\CG1643; Dmel_CG1643; hAPG5; hypothetical protein LOC532686; LD34980p; Paddy; XELAEV_18027227mg; zgc:100934

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11793, 365601, 9474

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535340

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Antigen:
DNMT1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.:
P13864, P26358, Q9Z330

Gene Symbols:
DNMT1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DNMT1 (NP_0013701)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Clone:
1K5K8

Conjugate:
Unconjugated

Gene:
DNMT1

Gene Alias:
ADCADN; AIM; CXXC9; CXXC-type zinc finger protein 9; DNA (cytosine-5-)-methyltransferase 1; DNA (cytosine-5)-methyltransferase 1; DNA methyltransferase (cytosine-5) 1; DNA methyltransferase 1; DNA methyltransferase HsaI; DNA methyltransferase I; DNA methyltransferase MmuI; DNA MTase HsaI; DNA MTase MmuI; DNA MTase RnoIP; DNMT; Dnmt1; Dnmt1o; FLJ16293; HSN1E; m.HsaI; m.MmuI; m.RnoIP; MCMT; Met1; Met-1; MGC104992; MommeD2; MTase; Uim

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13433, 1786, 84350

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535341

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Antigen:
Cathepsin D

Classification:
Monoclonal

Concentration:
0.25 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P07339, P18242

Gene Symbols:
Ctsd

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 313-412 of human Cathepsin D (P07339)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
ARC0160

Conjugate:
Unconjugated

Gene:
Ctsd

Gene Alias:
CatD; Cathepsin D; Cathepsin D heavy chain; Cathepsin D light chain; CathepsinD; CD; Ceroid lipofuscinosis neuronal 10; ceroid-lipofuscinosis, neuronal 10; CLN10; CPSD; CTSD; epididymis secretory sperm binding protein Li 130P; HEL-S-130P; lysosomal aspartyl peptidase; lysosomal aspartyl protease; MGC2311; OTTHUMP00000196039; OTTHUMP00000198692

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13033, 1509

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535343

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Antigen:
cIAP1

Classification:
Monoclonal

Concentration:
2.25 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q13490

Gene Symbols:
BIRC2

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human cIAP1 (Q13490)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
ARC0168

Conjugate:
Unconjugated

Gene:
BIRC2

Gene Alias:
Api1; Api2; apoptosis inhibitor 1; apoptosis inhibitor 2; AW146227; baculoviral IAP repeat containing 2; baculoviral IAP repeat-containing 2; baculoviral IAP repeat-containing 3; baculoviral IAP repeat-containing protein 2; baculoviral IAP repeat-containing protein 2; putative inhibitor of apoptosis; BIRC2; Birc3; cellular inhibitor of apoptosis 1; cIAP1; C-IAP1; cIAP2; HIAP1; HIAP2; Hiap-2; IAP homolog B; IAP1; IAP2; IAP-2; inhibitor of apoptosis protein; inhibitor of apoptosis protein 2; LOC100622859; mcIAP1; MIAP1; MIAP2; mIAP-2; MIHB; MIHC; NFR2-TRAF signalling complex protein; rIAP1; RING finger protein 48; RING-type E3 ubiquitin transferase BIRC2; RNF48; TNFR2-TRAF-signaling complex protein 2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
329, 60371

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid