PIMA535458

Apolipoprotein B Recombinant Rabbit Monoclonal Antibody (ARC0920), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA535458-Each-of-1 In Stock ₹ 45,132.90

PIMA535458 - Each of 1

₹ 45,132.90

In Stock

Quantity

1

Base Price: ₹ 45,132.90

GST (18%): ₹ 8,123.922

Total Price: ₹ 53,256.822

Antigen

Apolipoprotein B

Classification

Monoclonal

Concentration

0.67 mg/mL

Formulation

PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

E9Q414, Q7TMA5

Gene Symbols

APOB

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human ApoB (P04114)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Clone

ARC0920

Conjugate

Unconjugated

Gene

APOB

Gene Alias

Aa1064; Ac1-060; AI315052; Apo B100; Apo B-100; Apo B-48; APOB; apo-B; ApoB 100; ApoB 48; ApoB-100; apob-48; apolipo b; apolipoprotein B; apolipoprotein B (including Ag(x) antigen); Apolipoprotein B 100; Apolipoprotein B 48; apolipoprotein B PI; Apolipoprotein B100; apolipoprotein B-100; apolipoprotein B46; apolipoprotein B47; apolipoprotein B48; Apolipoprotein B-48; apolipoprotein B49; FLDB; LDLCQ4; LOX-1; mCG_129875; MGC176318; Ox-LDL receptor 1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

238055, 54225

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Immunogen sequence: RKYTYNYEAE SSSGVPGTAD SRSATRINCK VELEVPQLCS FILKTSQCTL KEVYGFNPEG KALLKKTKNS EEFAAAMSRY ELKLAIPEGK QVFLYPEKDE P Apolipoprotein B (apo B) in human plasma is a major protein of low density lipoproteins (LDL) with a molecular mass of approximately 260-500 kDa
  • Apolipoprotein B binds to specific receptors on cell membranes and is involved in removal of LDL and very low density lipoprotein (VLDL) cholesterol from circulation
  • Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood
  • LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearance of cholesterol from the circulation
  • In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36
  • Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described
  • MDA-oxidized LDL appear to be different from LDL oxidized by other means
  • Apolipoprotein B is mostly synthesized in the liver, and is a major apolipoprotein of very low density, intermediate density and low density lipoproteins (LDL) as well as being a major component of lipoprotein (a)
  • Apolipoprotein B is a ligand for the LDL receptor and elevated levels are associated with premature atherosclerosis
  • Normal plasma apolipoprotein B levels are around 800mg/L
  • Apolipoprotein B occurs in plasma as two main isoforms, apoB-48 and apoB-100
  • The intestinal and the hepatic forms of Apolipoprotein B are encoded by a single gene from a single, very long mRNA
  • The two isoforms share a common N-terminal sequence
  • The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination
  • Mutations in the Apolipoprotein B gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective Apolipoprotein B, diseases affecting plasma cholesterol and Apolipoprotein B levels.

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Thermo Scientific

PIMA535458

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Antigen:
Apolipoprotein B

Classification:
Monoclonal

Concentration:
0.67 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
E9Q414, Q7TMA5

Gene Symbols:
APOB

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human ApoB (P04114)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ARC0920

Conjugate:
Unconjugated

Gene:
APOB

Gene Alias:
Aa1064; Ac1-060; AI315052; Apo B100; Apo B-100; Apo B-48; APOB; apo-B; ApoB 100; ApoB 48; ApoB-100; apob-48; apolipo b; apolipoprotein B; apolipoprotein B (including Ag(x) antigen); Apolipoprotein B 100; Apolipoprotein B 48; apolipoprotein B PI; Apolipoprotein B100; apolipoprotein B-100; apolipoprotein B46; apolipoprotein B47; apolipoprotein B48; Apolipoprotein B-48; apolipoprotein B49; FLDB; LDLCQ4; LOX-1; mCG_129875; MGC176318; Ox-LDL receptor 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
238055, 54225

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535461

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Antigen:
Aquaporin 1

Classification:
Monoclonal

Concentration:
0.28 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P29972, P29975, Q02013

Gene Symbols:
Aqp1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 170-269 of human Aquaporin-1 (Aquaporin-1 (AQP1)) (P29972)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
ARC0925

Conjugate:
Unconjugated

Gene:
Aqp1

Gene Alias:
AQP 1; AQP CHIP; Aqp1; AQP-1; AQP-CHIP; aquaporin 1; Aquaporin 1 (aquaporin channel forming integral protein 28 (CHIP)); aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group); aquaporin 1 (Colton blood group); aquaporin 1, Colton blood group antigen; Aquaporin CHIP; Aquaporin1; aquaporin-1; Aquaporin-CHIP; channel-like integral membrane protein, 28-kDa; CHIP 28; CHIP28; CO; Colton blood group; Delayed early response protein 2; DER2; growth factor-induced delayed early response protein; membrane channel; MGC26324; urine water channel; Water channel protein for red blood cells and kidney proximal tubule

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11826, 25240, 358

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535463

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Antigen:
CPS1

Classification:
Monoclonal

Concentration:
0.33 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P07756, P31327, Q8C196

Gene Symbols:
CPS1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CPS1 (NP_0018662)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
ARC0929

Conjugate:
Unconjugated

Gene:
CPS1

Gene Alias:
4732433M03Rik; carbamoyl-phosphate synthase (ammonia); carbamoyl-phosphate synthase [ammonia], mitochondrial; carbamoyl-phosphate synthase 1; carbamoyl-phosphate synthase 1, mitochondrial; carbamoyl-phosphate synthetase 1; carbamoyl-phosphate synthetase 1, mitochondrial; carbamoylphosphate synthetase I; carbamoyl-phosphate synthetase I; carbamyl phosphate synthetase I; carboamyl-phosphate synthetase 1; cps; CPS1; CPSase I; CPSASE1; CPSI; D1Ucla3; PHN

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1373, 227231, 497840

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535464

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Antigen:
POLD1

Classification:
Monoclonal

Concentration:
1.15 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O54747, P28340, P52431

Gene Symbols:
POLD1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1000-1107 of human POLD1 (P28340)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ARC0930

Conjugate:
Unconjugated

Gene:
POLD1

Gene Alias:
125kDa; CDC2; CDC2 homolog; CRCS10; DAN polymerase delta 1, catalytic subunit; DNA polymerase delta 1, catalytic domain; DNA polymerase delta catalytic subunit; DNA polymerase delta, catalytic subunit; DNA polymerase subunit delta p125; DNA-directed DNA polymerase delta 1; MDPL; POL D; POLD; POLD1; polymerase (DNA directed), delta 1, catalytic subunit; polymerase (DNA directed), delta 1, catalytic subunit 125kDa; polymerase (DNA) delta 1, catalytic subunit; Polymerase D

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18971, 5424, 59294

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid