PIMA535883

Phospho-ErbB3 (Tyr1222) Recombinant Rabbit Monoclonal Antibody (ARC1599), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA535883-Each-of-1 In Stock ₹ 48,640.86

PIMA535883 - Each of 1

₹ 48,640.86

In Stock

Quantity

1

Base Price: ₹ 48,640.86

GST (18%): ₹ 8,755.355

Total Price: ₹ 57,396.215

Antigen

Phospho-ErbB3 (Tyr1222)

Classification

Monoclonal

Concentration

0.58 mg/mL

Formulation

PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P21860

Gene Symbols

ERBB3

Immunogen

A synthetic phosphorylated peptide around Y1222 of human ERBB3 (P21860)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Clone

ARC1599

Conjugate

Unconjugated

Gene

ERBB3

Gene Alias

avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2065

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Description

  • Immunogen sequence: LGYEY ErbB3 (c-erbB-3/HER-3) is a member of the type I family of growth factor receptors and binds to ligands in the heregulin family
  • ErbB3 is over-expressed in a variety of tumors in the prostate, bladder, breast, stomach, pancreas, and colon
  • Heregulin and EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents
  • The ErbB3 gene is located on the long arm of human chromosome 12 (12q13) and is transcribed into a 6
  • 2kb mRNA which is translated into a 160/180 kDa glycoprotein
  • The ErbB3 gene encodes a transmembrane receptor tyrosine kinase due to alternative splicing and forms heterodimers with other EGF receptor family members that have kinase activity
  • Heterodimerization leads to the activation of pathways that lead to cell proliferation or differentiation
  • Alternate transcriptional splice variants encoding different isoforms of ErbB3 have been characterized
  • One ErbB3 isoform lacks the intermembrane region, is secreted outside the cell, and acts to modulate the activity of the membrane-bound form
  • Additional splice variants have also been reported, but they have not been thoroughly characterized.

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Img

Thermo Scientific

PIMA535883

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Antigen:
Phospho-ErbB3 (Tyr1222)

Classification:
Monoclonal

Concentration:
0.58 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P21860

Gene Symbols:
ERBB3

Immunogen:
A synthetic phosphorylated peptide around Y1222 of human ERBB3 (P21860)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ARC1599

Conjugate:
Unconjugated

Gene:
ERBB3

Gene Alias:
avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2065

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535888

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Antigen:
Phospho-CDK1/CDK2/CDK3 (Thr14)

Classification:
Monoclonal

Concentration:
0.4 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P06493, P11440, P24941, P39951, P97377, Q00526, Q63699

Gene Symbols:
CDK1, CDK2, CDK3

Immunogen:
A synthetic phosphorylated peptide around T14 of human CDK1/2/3CDK1 (P06493)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ARC1545

Conjugate:
Unconjugated

Gene:
CDK2

Gene Alias:
2310050O10Rik; A630093N05Rik; CDC2; CDC28A; Cdc2a; cdc2-related protein kinase; CDK1; CDK2; CDK3; Cdk3-ps; CDKN1; CDKN2; CDKN3; cell cycle controller CDC2; cell cycle p34 CDC2 kinase protein; cell division control protein 2 homolog; cell division cycle 2 homolog A; cell division cycle 2, G1 to S and G2 to M; Cell division cycle control protein 2; cell division cycle control protein 2a; cell division protein kinase 1; Cell division protein kinase 2; cell division protein kinase 3; cyclin dependent kinase 1; cyclin dependent kinase 2; cyclin dependent kinase 2-alpha; cyclin dependent kinase 3; cyclin-dependent kinase 1; Cyclin-dependent kinase 2; cyclin-dependent kinase 3; cyclin-dependent kinase 3, pseudogene; p33 protein kinase; p33(CDK2); p34 protein kinase; p34<CDC2>; P34CDC2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1017, 1018, 12534, 12566, 362817, 54237, 69681, 983

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535890

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Antigen:
Phospho-Cdc37 (Ser13)

Classification:
Monoclonal

Concentration:
0.09 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q16543, Q61081, Q63692

Gene Symbols:
CDC37

Immunogen:
A synthetic phosphorylated peptide around S13 of human CDC37 (Q16543)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ARC1602

Conjugate:
Unconjugated

Gene:
CDC37

Gene Alias:
CDC 37; CDC37; CDC37 (cell division cycle 37 S. cerevisiae homolog); CDC37 (cell division cycle 37, S. cerevisiae, homolog); CDC37 cell division cycle 37 homolog; Cdc37 homolog; CDC37 protein; CDC37A; Cdc37p; Cell division control protein 37; cell division cycle 37; cell division cycle 37 homolog; hsp90 chaperone protein kinase-targeting subunit; Hsp90 co-chaperone Cdc37; Hsp90 co-chaperone Cdc37, N-terminally processed; p50; P50CDC37; SMO1; YD9489.03; YDR168W

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11140, 114562, 12539

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA535892

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Antigen:
Phospho-SMC1 (Ser957)

Classification:
Monoclonal

Concentration:
0.61 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q14683, Q8NDV3, Q920F6, Q9CU62, Q9Z1M9

Gene Symbols:
SMC1A, SMC1B

Immunogen:
A synthetic phosphorylated peptide around S957 of human SMC1 (Q14683)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
ARC1606

Conjugate:
Unconjugated

Gene:
SMC1A

Gene Alias:
14S cohesin SMC1 subunit; 5830426I24Rik; CDLS2; chromosome segregation protein SmcB; DKFZp686L19178; DXhXs423e; DXS423E; KIAA0178; MGC138332; mitosis-specific chromosome segregation protein like protein beta; mKIAA0178; RP6-29D12.1; Sb1.8; segregation of mitotic chromosomes 1; segregation of mitotic chromosomes b; segregation of mitotic chromosomes-like 1; SM1A; SMC; SMC (segregation of mitotic chromosomes 1)-like 1; SMC protein; SMC protein 1A; SMC protein 1B; SMC1; SMC1 (structural maintenance of chromosomes 1, yeast)-like 1; SMC1 protein; SMC1 protein cohesin subunit; SMC1 structural maintenance of chromosomes 1-like 1; SMC1 structural maintenance of chromosomes 1-like 2; Smc1a; SMC-1A; smc1a.L; smc1aa; Smc1alpha; SMC-1-alpha; SMC1alpha protein; Smc1b; SMC-1B; SMC1BETA; SMC-1-beta; SMC1L1; Smc1l2; Smcb; SMC-like 1; SMC-protein; structural maintenace of chromosomes 1B; structural maintenance of chromosomes 1; structural maintenance of chromosomes 1 like 1; structural maintenance of c

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
140557, 24061, 27127, 300121, 63996, 8243

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid