PIMA537269

Phospho-Chk2 (Thr68) Recombinant Rabbit Monoclonal Antibody (Chk2T68-D12), FITC, Invitrogen™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA537269-Each-of-1 In Stock ₹ 18,994.32

PIMA537269 - Each of 1

₹ 18,994.32

In Stock

Quantity

1

Base Price: ₹ 18,994.32

GST (18%): ₹ 3,418.978

Total Price: ₹ 22,413.298

Antigen

Phospho-Chk2 (Thr68)

Classification

Monoclonal

Conjugate

FITC

Gene

Chek2

Gene Alias

CDS1; cds1 homolog; Checkpoint kinase 2; Checkpoint like protein CHK2; checkpoint-like protein CHK2; Chek2; Chk2; Chk2 (phospho T68); Chk2 (pThr68); CHK2 checkpoint homolog; CHK2 checkpoint homolog (S. pombe); Chk2 phospho; Chk2 phospho T68; del9; EC 2.7.11.1; hCds1; HuCds 1; HuCds1; kinase Chk2; LFS2; OTTHUMP00000199044; OTTHUMP00000199045; OTTHUMP00000199064; OTTHUMP00000199115; OTTHUMP00000199116; phospho Chk2 (T68); phospho Thr68 Chk2; PP1425; protein kinase Chk2; Rad53; Rad53 homolog; RP11-436C9.1; Serine/threonine protein kinase Chk2; serine/threonine-protein kinase Chk2

Host Species

Rabbit

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

11200, 50883

Content And Storage

4° C, store in dark

Form

Liquid

Applications

Flow Cytometry

Clone

Chk2T68-D12

Formulation

PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.

O96017, Q9Z265

Gene Symbols

Chek2

Immunogen

A synthetic phosphor-peptide corresponding to residues surrounding to Thr68 of human phospho Chk2.

Quantity

10 Tests

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG κ

Description

  • CHEK2 (CHK2) is a serine/threonine kinase and a component of the DNA damage checkpoint pathway
  • A mutation in CHK2 has been linked to cancer
  • CHK2 is activated by DNA damage and phosphorylates several modulators of cell cycle control including tumor suppressor proteins
  • In addition, Chk2 can phosphorylate BRCA1, allowing BRCA1 to restore survival after DNA damage
  • Chk2 is a putative tumor suppressor protein, with mutations in to the Chk2 gene linked to Li-Fraumeni syndrome, a familiar cancer usually associated with inherited mutations in TP53
  • Also, mutations in CHK2 are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors.

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Img

Fischer Scientific

PIMA537269

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Antigen:
Phospho-Chk2 (Thr68)

Classification:
Monoclonal

Conjugate:
FITC

Gene:
Chek2

Gene Alias:
CDS1; cds1 homolog; Checkpoint kinase 2; Checkpoint like protein CHK2; checkpoint-like protein CHK2; Chek2; Chk2; Chk2 (phospho T68); Chk2 (pThr68); CHK2 checkpoint homolog; CHK2 checkpoint homolog (S. pombe); Chk2 phospho; Chk2 phospho T68; del9; EC 2.7.11.1; hCds1; HuCds 1; HuCds1; kinase Chk2; LFS2; OTTHUMP00000199044; OTTHUMP00000199045; OTTHUMP00000199064; OTTHUMP00000199115; OTTHUMP00000199116; phospho Chk2 (T68); phospho Thr68 Chk2; PP1425; protein kinase Chk2; Rad53; Rad53 homolog; RP11-436C9.1; Serine/threonine protein kinase Chk2; serine/threonine-protein kinase Chk2

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
11200, 50883

Content And Storage:
4° C, store in dark

Form:
Liquid

Applications:
Flow Cytometry

Clone:
Chk2T68-D12

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
O96017, Q9Z265

Gene Symbols:
Chek2

Immunogen:
A synthetic phosphor-peptide corresponding to residues surrounding to Thr68 of human phospho Chk2.

Quantity:
10 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Img

Fischer Scientific

PIMA537271

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Antigen:
Phospho-CREB (Ser133)

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
CREB1

Gene Alias:
2310001E10Rik; 3526402H21Rik; active transcription factor CREB; AV083133; cAMP response element binding protein 1; cAMP responsive element binding protein 1; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1; CREB; CREB1; Creb-1; cyclic adenosine 3',5'-monophosphate response element-binding protein CREB; cyclic AMP-responsive element-binding protein 1; htCREB; MGC9284; OTTHUMP00000206661; OTTHUMP00000206662; OTTHUMP00000206667; transactivator protein; Y protein

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
12912, 1385

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Clone:
CREBS133-4D11

Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P16220, Q01147

Gene Symbols:
CREB1

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser133 of human phospho CREB.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Img

Fischer Scientific

PIMA537273

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Antigen:
Phospho-CREB (Ser133)

Classification:
Monoclonal

Conjugate:
FITC

Gene:
CREB1

Gene Alias:
2310001E10Rik; 3526402H21Rik; active transcription factor CREB; AV083133; cAMP response element binding protein 1; cAMP responsive element binding protein 1; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1; CREB; CREB1; Creb-1; cyclic adenosine 3',5'-monophosphate response element-binding protein CREB; cyclic AMP-responsive element-binding protein 1; htCREB; MGC9284; OTTHUMP00000206661; OTTHUMP00000206662; OTTHUMP00000206667; transactivator protein; Y protein

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
12912, 1385

Content And Storage:
4° C, store in dark

Form:
Liquid

Applications:
Flow Cytometry

Clone:
CREBS133-4D11

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
P16220, Q01147

Gene Symbols:
CREB1

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser133 of human phospho CREB.

Quantity:
10 Tests

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Img

Fischer Scientific

PIMA537274

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Antigen:
Phospho-PTEN (Ser380, Thr382, Thr383)

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene:
PTEN

Gene Alias:
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
19211, 5728

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Clone:
PTENS380T382383-E4

Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
O08586, P60484

Gene Symbols:
PTEN

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser380 and Thr382/383 of human phospho PTEN.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ