PIMA537585

VDR Monoclonal Antibody (517CT23.5.1), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA537585-Each-of-1 In Stock ₹ 45,646.26

PIMA537585 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

VDR

Classification

Monoclonal

Concentration

2 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P11473

Gene Symbols

VDR

Immunogen

purified His-tagged VDR protein (fragment)

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgA

Applications

Western Blot

Clone

517CT23.5.1

Conjugate

Unconjugated

Gene

VDR

Gene Alias

1,25-dihydroxyvitamin D3 receptor; HGNC:12679; I79_025795; Nr1i1; Nuclear receptor subfamily 1 group I member 1; PPP1R163; protein phosphatase 1, regulatory subunit 163; vdr; vdr.S; vdr-A; vitamin D (1,25- dihydroxyvitamin D3) receptor; vitamin D (1,25- dihydroxyvitamin D3) receptor S homeolog; vitamin D (1,25-dihydroxyvitamin D3) receptor; vitamin D nuclear receptor variant 1; vitamin D receptor; vitamin D receptor protein; vitamin D receptor S homeolog; Vitamin D3 receptor; XELAEV_18015993mg; xVDR

Host Species

Mouse

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

7421

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Steroid receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone
  • The 1,25-dihydroxy-vitamin D3 receptor (VDR) belongs to the superfamily of steroid hormone receptors which includes estrogen, progesterone, glucocorticoid, androgen, and thyroid hormone receptors
  • Vitamin D modulates calcium and phosphorus homeostasis, bone remodeling, cell growth regulation, and differentiation
  • Studies have found VDR in the intestine, bone, kidney, epidermis, and cells of the endocrine immune system
  • Repression of T-cell proliferation and interleukin-2 (IL-2) gene expression, for example, occurs when VDR binds within the IL-2 enhancer
  • Formation of VDR/retinoic X receptor (RXR) heterodimers in the presence of intracellular 1,25(OH)2D3 has been shown to interfere with assembly of nuclear factor of activated T-cells (NFATp)/Fos/Jun/DNA complex and subsequent IL-2 gene transcription
  • The corresponding gene for the vitamin D receptor is NR1I1.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA537585

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Antigen:
VDR

Classification:
Monoclonal

Concentration:
2 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P11473

Gene Symbols:
VDR

Immunogen:
purified His-tagged VDR protein (fragment)

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgA

Applications:
Western Blot

Clone:
517CT23.5.1

Conjugate:
Unconjugated

Gene:
VDR

Gene Alias:
1,25-dihydroxyvitamin D3 receptor; HGNC:12679; I79_025795; Nr1i1; Nuclear receptor subfamily 1 group I member 1; PPP1R163; protein phosphatase 1, regulatory subunit 163; vdr; vdr.S; vdr-A; vitamin D (1,25- dihydroxyvitamin D3) receptor; vitamin D (1,25- dihydroxyvitamin D3) receptor S homeolog; vitamin D (1,25-dihydroxyvitamin D3) receptor; vitamin D nuclear receptor variant 1; vitamin D receptor; vitamin D receptor protein; vitamin D receptor S homeolog; Vitamin D3 receptor; XELAEV_18015993mg; xVDR

Host Species:
Mouse

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
7421

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA537586

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Antigen:
Arylsulfatase A

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P15289

Gene Symbols:
ARSA

Immunogen:
KLH conjugated synthetic peptide between 408-439 amino acids from the C-terminal region of human ARSA

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
498CT24.1.2

Conjugate:
Unconjugated

Gene:
ARSA

Gene Alias:
ARSA; ARSA1; ARSA-I; Arylsulfatase A; Arylsulfatase A component B; Arylsulfatase A component C; As2; As-2; ASA; AS-A; ASNA-I; ATPase ASNA1; AW212749; cerebroside-sulfatase; EC 3.1.6.8; GET3; hASNA-I; MLD; TISP73; TRC40

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
410

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA537587

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Antigen:
Torsin 1A

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.09% sodium azide

Gene Accession No.:
O14656

Gene Symbols:
Tor1a

Immunogen:
purified His-tagged DYT1 protein (fragment)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
583CT1.1.3

Conjugate:
Unconjugated

Gene:
Tor1a

Gene Alias:
DQ2; dystonia 1; Dystonia 1 protein; Dystonia 1 torsion; dystonia 1, torsion (autosomal dominant; dystonia 1, torsion (autosomal dominant; torsin A); DYT1; LOW QUALITY PROTEIN: torsin-1A; TA; Tor1a; TORA; Torsin 1A; torsin A; torsin ATPase 1; Torsin ATPase-1A; torsin family 1 member A; torsin family 1, member A; torsin family 1, member A (torsin A); torsin-1A; torsinA

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
1861

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA537589

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Antigen:
TOP2A

Classification:
Monoclonal

Concentration:
Conc. not determined

Formulation:
ascites with 0.09% sodium azide

Gene Accession No.:
P11388

Gene Symbols:
TOP2A

Immunogen:
purified His-tagged TOP2A protein (fragment)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
548CT6.1.1

Conjugate:
Unconjugated

Gene:
TOP2A

Gene Alias:
DNA gyrase; DNA topoisomerase (ATP-hydrolyzing); DNA topoisomerase 2-alpha; DNA topoisomerase 2-alpha-like protein; DNA Topoisomerase II alpha; DNA topoisomerase II, 170 kD; DNA topoisomerase II, alpha isozyme; EC 5.99.1.3; OTTHUMP00000207108; P11388-1; TOP2; Top-2; Top2a; TOPOII; topoisomerase (DNA) 2 alpha; topoisomerase (DNA) II alpha; topoisomerase (DNA) II alpha 170kDa; topoisomerase ii alpha; topoisomersae II; TP2A

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
7153

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid