PIMA542446

INSR beta Recombinant Rabbit Monoclonal Antibody (SN20-13), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA542446-Each-of-1 In Stock ₹ 44,020.62

PIMA542446 - Each of 1

₹ 44,020.62

In Stock

Quantity

1

Base Price: ₹ 44,020.62

GST (18%): ₹ 7,923.712

Total Price: ₹ 51,944.332

Antigen

INSR beta

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

P06213, P15127, P15208

Gene Symbols

INSR

Immunogen

Synthetic peptide within human Insulin receptor aa 930-970

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Western Blot

Clone

SN20-13

Conjugate

Unconjugated

Gene

INSR

Gene Alias

4932439J01Rik; CD220; CD220 beta; CD221; D630014A15Rik; HHF5; IGF-I receptor; Insr; Insulin receptor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR beta; IR-A; IR-B

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

16337, 24954, 3643

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Positive Control: MCF-7 cell lysate, 293 cell lysate, HepG2, LO2, RH-35, PANC-1
  • Subcellular Location: Cell membrane
  • Biological actions of insulin and IGF-1 are mediated by their respective cell surface receptor tyrosine kinases that regulate multiple signaling pathways through activation of a series of phosphorylation cascades
  • The insulin receptor
  • Insulin/IGF-1 binding to the extracellular domain leads to autophosphorylation of downstream target proteins
  • These two receptors differ in sequence in regions that confer specificity for the designated ligand as well as in certain intracellular signaling domains, resulting in significant differences in the functional consequences of activation of each receptor
  • Defects in IR are the cause of various insulin resistance syndromes and IGF-1R defects may cause some forms of growth retardation
  • Both these signaling cascades are also important for the development of cancer.

Compare Similar Items

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Img

Thermo Scientific

PIMA542446

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Antigen:
INSR beta

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P06213, P15127, P15208

Gene Symbols:
INSR

Immunogen:
Synthetic peptide within human Insulin receptor aa 930-970

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
SN20-13

Conjugate:
Unconjugated

Gene:
INSR

Gene Alias:
4932439J01Rik; CD220; CD220 beta; CD221; D630014A15Rik; HHF5; IGF-I receptor; Insr; Insulin receptor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR beta; IR-A; IR-B

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
16337, 24954, 3643

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA542448

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Antigen:
PSA

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P07288

Gene Symbols:
KLK3

Immunogen:
Recombinant protein within human prostate specific antigen aa 198-261

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
SD07-45

Conjugate:
Unconjugated

Gene:
KLK3

Gene Alias:
Antigen; antigen, prostate specific; APS; Fletcher factor; gamma-seminoprotein; hK3; Kal3; Kal-3; Kallikrein 3; kallikrein 3, plasma; kallikrein B, plasma 1; kallikrein related peptidase 3; kallikrein-3; Kallikrein-3 (KLK3); kallikrein-related peptidase 3; Kalp1; KALP15; Kininogenin; KLK2A1; Klk3; KLK-3; Klkb1; P-30 antigen; Pk; Plasma kallikrein; Plasma kallikrein heavy chain; Plasma kallikrein light chain; Plasma prekallikrein; prostate specific antigen; prostate-specific (APS); prostate-specific antigen; PSA; Semenogelase; seminin

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
354

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA542450

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Antigen:
Phospho-EGFR (Tyr1068)

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05%% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P00533

Gene Symbols:
EGFR

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Tyr1068 of human EGFR

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
SD2055

Conjugate:
Unconjugated

Gene:
EGFR

Gene Alias:
2.7.10.1; 9030024J15Rik; AI552599; avian erythroblastic leukemia viral (v-erbB) oncogene homolog; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; EC 2.7.10.1; egf receptor; Egfr; EGFR-related peptide; epidermal growth factor receptor; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1); ERBB; ERBB1; ErbB-1; erb-b2 receptor tyrosine kinase 1; Errb1; Errp; HER1; kinase EGFR; mENA; NISBD2; Oncogene ERBB; PIG61; Proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1; Urogastrone; wa2; wa-2; Wa5; waved 2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1956

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA542451

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Antigen:
Tau

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P10636, P10637, P19332

Gene Symbols:
MAPT

Immunogen:
Synthetic peptide within human Tau aa 600-640

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Clone:
SD205-09

Conjugate:
Unconjugated

Gene:
MAPT

Gene Alias:
AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
17762, 29477, 4137

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid