PIMA537592
DISC1 Monoclonal Antibody (584CT4.2.1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA537592-Each-of-1 | In Stock | ₹ 45,646.26 |
PIMA537592 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,646.26
GST (18%): ₹ 8,216.327
Total Price: ₹ 53,862.587
Antigen
DISC1
Classification
Monoclonal
Conjugate
Unconjugated
Gene
DISC1
Gene Alias
C1orf136; DISC1; disrupted in schizophrenia 1; disrupted in schizophrenia 1 homolog; Disrupted in schizophrenia 1 protein; KIAA0457; RP4-730B13.1; SCZD9
Host Species
Mouse
Purification Method
Euglobulin precipitation
Regulatory Status
RUO
Gene ID (Entrez)
27185
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Clone
584CT4.2.1
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
Q9NRI5
Gene Symbols
DISC1
Immunogen
KLH conjugated synthetic peptide between 701-728 amino acids from human DISC1
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgM
Related Products
Description
- DISC1 (Disrupted in Schizophrenia 1) is a multifunctional protein that interacts with multiple proteins of the centrosome and cytoskeletal system, and is involved in neuronal functions that are dependent upon proper cytoskeletal regulation, including neuronal migration, neurite architecture and intracellular transport
- Regions of the brain which express DISC1 include the hippocampus, lateral septum, amygdala, cerebral cortex, cerebellum and paraventricular hypothalamus, and loss of DISC1 function results in differences in structural organization.The DISC1 gene locus is associated with patients afflicted with schizophrenia as a result of chromosomal translocations
- DISC-1 encodes a large protein predicted to contain a globular N-terminal domain and a helical C-terminal domain, both of which have the potential to form interactions with other proteins
- DISC-1 interacts with proteins involved in the centrosome and cytoskeletal system, including MIPT3, MAP1A and NUDEL; proteins which localize receptors to membranes, including alpha-actinin 2, beta 4-spectrin; and proteins which transduce signals from membrane receptors, including ATF-4 and ATF-5
- Therefore, DISC-1 is thought to be involved in intracellular transport, neurite architecture and/or neuronal migration, all of which are thought to be pathogenic in the schizophrenic brain
- Decreased expression of DISC1 in neurons caused an accelerated rate of neuronal integration, resulting in aberrant morphological development, suggesting that DISC1 plays a role in dendritic development and synapse formation
- DISC-1 is thought to be involved in intracellular transport, neurite architecture and/or neuronal migration, all of which are thought to be pathogenic in the schizophrenic brain.
Compare Similar Items
Show Difference
Antigen: DISC1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: DISC1
Gene Alias: C1orf136; DISC1; disrupted in schizophrenia 1; disrupted in schizophrenia 1 homolog; Disrupted in schizophrenia 1 protein; KIAA0457; RP4-730B13.1; SCZD9
Host Species: Mouse
Purification Method: Euglobulin precipitation
Regulatory Status: RUO
Gene ID (Entrez): 27185
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Clone: 584CT4.2.1
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q9NRI5
Gene Symbols: DISC1
Immunogen: KLH conjugated synthetic peptide between 701-728 amino acids from human DISC1
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgM
Antigen:
DISC1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
DISC1
Gene Alias:
C1orf136; DISC1; disrupted in schizophrenia 1; disrupted in schizophrenia 1 homolog; Disrupted in schizophrenia 1 protein; KIAA0457; RP4-730B13.1; SCZD9
Host Species:
Mouse
Purification Method:
Euglobulin precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
27185
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Clone:
584CT4.2.1
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q9NRI5
Gene Symbols:
DISC1
Immunogen:
KLH conjugated synthetic peptide between 701-728 amino acids from human DISC1
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgM
Antigen: GATA4
Classification: Monoclonal
Conjugate: Unconjugated
Gene: GATA4
Gene Alias: ASD2; DNA-binding protein GATA-GT2; GAT4; GATA binding protein 4; GATA4; Gata-4; GATA-binding factor 4; GATA-binding protein 4; MGC126629; TACHD; TOF; Transcription factor GATA-4; VSD1
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): 2626
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Clone: 570CT10.5.7
Formulation: ascites with 0.09% sodium azide
Gene Accession No.: P43694
Gene Symbols: GATA4
Immunogen: KLH conjugated synthetic peptide between 298-328 amino acids from the C-terminal region of human GATA4
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgM
Antigen:
GATA4
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
GATA4
Gene Alias:
ASD2; DNA-binding protein GATA-GT2; GAT4; GATA binding protein 4; GATA4; Gata-4; GATA-binding factor 4; GATA-binding protein 4; MGC126629; TACHD; TOF; Transcription factor GATA-4; VSD1
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
2626
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Clone:
570CT10.5.7
Formulation:
ascites with 0.09% sodium azide
Gene Accession No.:
P43694
Gene Symbols:
GATA4
Immunogen:
KLH conjugated synthetic peptide between 298-328 amino acids from the C-terminal region of human GATA4
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgM
Antigen: HNF1A
Classification: Monoclonal
Conjugate: Unconjugated
Gene: Hnf1a
Gene Alias: AI323641; albumin proximal factor; hepatic nuclear factor 1; hepatic nuclear factor-1-alpha; hepatocyte nuclear factor 1; hepatocyte nuclear factor 1-alpha; Hepatocyte nuclear factor 1-alpha-A; HNF1; Hnf-1; hnf-1 alpha; HNF1 homeobox A; HNF1 homeobox A L homeolog; HNF1 homeobox A S homeolog; HNF1[a]; hnf1a; Hnf-1a; hnf1-a; hnf1a.L; hnf1a.S; HNF-1A-A; hnf1a-a; hnf1a-b; Hnf1alpha; HNF-1-alpha; HNF1-alpha; HNF-1-alpha-A; I79_010330; IDDM20; interferon production regulator factor; LFB1; LF-B1; LF-B1 hepatic nuclear factor (HNF1): albumin proximal factor also TCF1; LF-B1, hepatic nuclear factor (HNF1): albumin proximal factor, also TCF1; lfb1a; LFB1a1; Liver-specific transcription factor LF-B1; MODY3; TCF1; Tcf-1; TCF-1-A; tcf1-a; transcription factor 1; Transcription factor 1 hepatic; Transcription factor 1, hepatic; transcription factor 1, transcription factor LFB1 /HNF1; transcription factor 1-A; XELAEV_18010473mg; XLFB1; XLFB1a; XLFB1b
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): 6927
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Clone: 622CT11.9.6
Formulation: ascites with 0.09% sodium azide
Gene Accession No.: P20823
Gene Symbols: Hnf1a
Immunogen: KLH conjugated synthetic peptide between 177-205 amino acids from human HNF1A
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
HNF1A
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
Hnf1a
Gene Alias:
AI323641; albumin proximal factor; hepatic nuclear factor 1; hepatic nuclear factor-1-alpha; hepatocyte nuclear factor 1; hepatocyte nuclear factor 1-alpha; Hepatocyte nuclear factor 1-alpha-A; HNF1; Hnf-1; hnf-1 alpha; HNF1 homeobox A; HNF1 homeobox A L homeolog; HNF1 homeobox A S homeolog; HNF1[a]; hnf1a; Hnf-1a; hnf1-a; hnf1a.L; hnf1a.S; HNF-1A-A; hnf1a-a; hnf1a-b; Hnf1alpha; HNF-1-alpha; HNF1-alpha; HNF-1-alpha-A; I79_010330; IDDM20; interferon production regulator factor; LFB1; LF-B1; LF-B1 hepatic nuclear factor (HNF1): albumin proximal factor also TCF1; LF-B1, hepatic nuclear factor (HNF1): albumin proximal factor, also TCF1; lfb1a; LFB1a1; Liver-specific transcription factor LF-B1; MODY3; TCF1; Tcf-1; TCF-1-A; tcf1-a; transcription factor 1; Transcription factor 1 hepatic; Transcription factor 1, hepatic; transcription factor 1, transcription factor LFB1 /HNF1; transcription factor 1-A; XELAEV_18010473mg; XLFB1; XLFB1a; XLFB1b
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
6927
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Clone:
622CT11.9.6
Formulation:
ascites with 0.09% sodium azide
Gene Accession No.:
P20823
Gene Symbols:
Hnf1a
Immunogen:
KLH conjugated synthetic peptide between 177-205 amino acids from human HNF1A
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: Tecrl
Classification: Monoclonal
Conjugate: Unconjugated
Gene: TECRL
Gene Alias: D330017N19Rik; glycoprotein, synaptic 2-like; GPSN2L; SRD5A2L2; steroid 5 alpha-reductase 2-like 2; steroid 5-alpha-reductase 2-like 2 protein; synaptic glycoprotein SC2-like; TECRL; TERL; trans-2,3-enoyl-CoA reductase like; trans-2,3-enoyl-CoA reductase-like; Unknown (protein for MGC:128084)
Host Species: Mouse
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): 253017
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Clone: 601CT22.4.3
Formulation: ascites with 0.09% sodium azide
Gene Accession No.: Q5HYJ1
Gene Symbols: TECRL
Immunogen: KLH conjugated synthetic peptide between 325-354 amino acids from the C-terminal region of human SRD5A2L2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
Tecrl
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
TECRL
Gene Alias:
D330017N19Rik; glycoprotein, synaptic 2-like; GPSN2L; SRD5A2L2; steroid 5 alpha-reductase 2-like 2; steroid 5-alpha-reductase 2-like 2 protein; synaptic glycoprotein SC2-like; TECRL; TERL; trans-2,3-enoyl-CoA reductase like; trans-2,3-enoyl-CoA reductase-like; Unknown (protein for MGC:128084)
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
253017
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Clone:
601CT22.4.3
Formulation:
ascites with 0.09% sodium azide
Gene Accession No.:
Q5HYJ1
Gene Symbols:
TECRL
Immunogen:
KLH conjugated synthetic peptide between 325-354 amino acids from the C-terminal region of human SRD5A2L2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1