PIMA537714

cGAS Monoclonal Antibody (1697CT136.65.30), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA537714-Each-of-1 In Stock ₹ 45,646.26

PIMA537714 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

cGAS

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q8N884

Gene Symbols

CGAS

Immunogen

KLH conjugated synthetic peptide between 1-185 amino acids from human MB21D1

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Applications

Western Blot

Clone

1697CT136.65.30

Conjugate

Unconjugated

Gene

CGAS

Gene Alias

C6orf150; h-cGAS; MB21D1

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

115004

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • cGAS (Cyclic GMP-AMP synthase) is a nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP) from ATP and GTP and plays a key role in innate immunity
  • Catalysis involves both the formation of 2', 5' phosphodiester linkage at the GpA step and the formation of 3', 5' phosphodiester linkage at the ApG step
  • This produces c[G(2',5')pA(3'5')p] responses
  • cGAS also binds cytosolic DNA directly, leading to the activation and synthesis of cGAMP
  • Then, a second messenger binds to and activates TMEM173/STING thereby triggering type-I interferon production
  • cGAS is also involved in innate immune sensorship of infection, detection of DNA from bacteria, response to cellular stress, DNA damage, and regulation of cellular senescence.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA537714

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Antigen:
cGAS

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q8N884

Gene Symbols:
CGAS

Immunogen:
KLH conjugated synthetic peptide between 1-185 amino acids from human MB21D1

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
1697CT136.65.30

Conjugate:
Unconjugated

Gene:
CGAS

Gene Alias:
C6orf150; h-cGAS; MB21D1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
115004

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA537715

--


Antigen:
WNT4

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P22724, P56705

Gene Symbols:
Wnt4

Immunogen:
recombinant protein between 30-351 amino acids from human WNT4

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
1698CT540.169.185

Conjugate:
Unconjugated

Gene:
Wnt4

Gene Alias:
protein Wnt-4; SERKAL; signal molecule; UNQ426/PRO864; wingless-related MMTV integration site 4; wingless-type MMTV integration site family member 4; wingless-type MMTV integration site family, member 4; Wnt family member 4; WNT4; Wnt-4

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
22417, 54361

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA537716

--


Antigen:
MYBBP1A

Classification:
Monoclonal

Concentration:
0.4 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q9BQG0

Gene Symbols:
MYBBP1A

Immunogen:
recombinant protein between 1104-1328 amino acids from human MYBBP1A

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
1702CT711.87.46

Conjugate:
Unconjugated

Gene:
MYBBP1A

Gene Alias:
AL024407, AU019902, DBP, MYB binding protein 1a, MYB binding protein (P160) 1a, MYB binding protein 1a, myb-binding protein 1A, Myb-binding protein of 160 kDa, MYBBP1A, nuclear protein P160, P160, p160MBP, p53-activated protein-2, p67MBP, PAP2, PAR interacting protein, PAR-interacting protein, PIP

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10514

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA537717

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Antigen:
AMPK beta-1

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P80386, Q9R078, Q9Y478

Gene Symbols:
PRKAB1

Immunogen:
recombinant of human PRKAB1

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
1420CT832.86.25

Conjugate:
Unconjugated

Gene:
PRKAB1

Gene Alias:
1300015D22Rik; 5'-AMP-activated protein kinase 40 kDa subunit; 5-AMP-activated protein kinase beta subunit; 5'-AMP-activated protein kinase beta-1 subunit; 5'-AMP-activated protein kinase subunit beta-1; 5'-AMP-activated protein kinase subunit beta-1-like protein; 5'-AMP-activated protein kinase, beta subunit; AAKB1; AMP-activated protein kinase beta subunit; AMPK; AMPK beta 1; AMPK beta -1 chain; AMPK beta-1 chain; AMPK subunit beta-1; AMPKb; AMPK-beta1; AU021155; E430008F22; HAMPKb; kinase AMPK-beta1; kinase pAMPK; pAMPK; Prkab1; protein kinase AMP-activated non-catalytic subunit beta 1; protein kinase, AMP-activated, beta 1 non-catalytic subunit; protein kinase, AMP-activated, noncatalytic, beta-1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
19079, 5564, 83803

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid