PIMA537711

ISG15 Monoclonal Antibody (1031CT2.8.3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA537711-Each-of-1 In Stock ₹ 44,619.54

PIMA537711 - Each of 1

₹ 44,619.54

In Stock

Quantity

1

Base Price: ₹ 44,619.54

GST (18%): ₹ 8,031.517

Total Price: ₹ 52,651.057

Antigen

ISG15

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P05161

Gene Symbols

ISG15

Immunogen

recombinant protein from human ISG15

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Applications

Immunocytochemistry, Western Blot

Clone

1031CT2.8.3

Conjugate

Unconjugated

Gene

ISG15

Gene Alias

G1P2; hUCRP; IFI15; IGI15; IMD38; interferon, alpha-inducible protein; interferon, alpha-inducible protein (clone IFI-15K); interferon-induced 15 kDa protein; interferon-induced 15-KDa protein; interferon-induced 17 kDa protein; interferon-induced 17-kDa/15-kDa protein; interferon-stimulated protein (15 kDa); interferon-stimulated protein 15; interferon-stimulated protein, 15 kDa; IP17; Irfp; Isg15; ISG15 ubiquitin like modifier; ISG15 ubiquitin-like modifier; ubiquitin cross-reactive protein; Ubiquitin-like protein ISG15; UCRP

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

9636

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Ubiquitin-like protein ISG15 plays a key role in the innate immune response to viral infection either via its conjugation to a target protein (ISGylation) or via its action as a free or unconjugated protein
  • It is secreted from monocytes in response to type I interferons and causes natural killer (NK)-cell proliferation and an augmentation of non-MCH (major histocompatibility complex)-restricted cytotoxicity
  • Synthesis is stimulated by IFN-alpha or IFN-beta or IFN-omega, but not IFN-gamma
  • ISG15 expression is also induced by overexpression of interferon regulatory factors that participate in transcriptional regulation of IFN genes, and by influenza B virus
  • ISG15 is secreted by cell lines of monocyte, T-lymphocyte, B-lymphocyte, human fibroblasts, and epithelial origins
  • Enhancement of NK cell proliferation, augmentation of non-major histocompatibility complex-restricted cytotoxicity, and induction of IFN-gamma from T cells identify ISG15 as a member of the cytokine cascade and suggest that it may be responsible for amplifying and directing some of the immunomodulatory effects of IFN-alpha or IFN-beta
  • ISG15 has has also been shown to function intracellularly as a ubiquitin homolog
  • Mutations affecting the gene can result in Immunodeficiency 38, with basal ganglia calcification (IMD38).

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA537711

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Antigen:
ISG15

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P05161

Gene Symbols:
ISG15

Immunogen:
recombinant protein from human ISG15

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Western Blot

Clone:
1031CT2.8.3

Conjugate:
Unconjugated

Gene:
ISG15

Gene Alias:
G1P2; hUCRP; IFI15; IGI15; IMD38; interferon, alpha-inducible protein; interferon, alpha-inducible protein (clone IFI-15K); interferon-induced 15 kDa protein; interferon-induced 15-KDa protein; interferon-induced 17 kDa protein; interferon-induced 17-kDa/15-kDa protein; interferon-stimulated protein (15 kDa); interferon-stimulated protein 15; interferon-stimulated protein, 15 kDa; IP17; Irfp; Isg15; ISG15 ubiquitin like modifier; ISG15 ubiquitin-like modifier; ubiquitin cross-reactive protein; Ubiquitin-like protein ISG15; UCRP

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
9636

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA537712

--


Antigen:
PGK1

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P00558, P09411

Gene Symbols:
PGK1

Immunogen:
KLH conjugated synthetic peptide between 1-417 amino acids from human

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
1086CT10.2.1

Conjugate:
Unconjugated

Gene:
PGK1

Gene Alias:
cell migration-inducing gene 10 protein; epididymis secretory sperm binding protein Li 68p; HEL-S-68p; MIG10; OK/SW-cl.110; Pgk; Pgk1; Pgk-1; PGKA; Phosphoglycerate kinase; phosphoglycerate kinase 1; Primer recognition protein 2; PRP 2; YCR012W; YCR12W

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
18655, 5230

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA537713

--


Antigen:
RAB20

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q9NX57

Gene Symbols:
Rab20

Immunogen:
recombinant protein from human RAB20

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Western Blot

Clone:
1694CT210.142.16

Conjugate:
Unconjugated

Gene:
Rab20

Gene Alias:
AA536966; D8Ertd350e; RAB20; RAB20, member RAS oncogene family; ras-related protein Rab-20

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
55647

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA537714

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Antigen:
cGAS

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q8N884

Gene Symbols:
CGAS

Immunogen:
KLH conjugated synthetic peptide between 1-185 amino acids from human MB21D1

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
1697CT136.65.30

Conjugate:
Unconjugated

Gene:
CGAS

Gene Alias:
C6orf150; h-cGAS; MB21D1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
115004

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid