PIMA541255

Securin Recombinant Rabbit Monoclonal Antibody (JB37-37), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA541255-Each-of-1 In Stock ₹ 44,961.78

PIMA541255 - Each of 1

₹ 44,961.78

In Stock

Quantity

1

Base Price: ₹ 44,961.78

GST (18%): ₹ 8,093.12

Total Price: ₹ 53,054.90

Antigen

Securin

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

O95997

Gene Symbols

Pttg1

Immunogen

Recombinant protein within C-terminal Human Securin

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

JB37-37

Conjugate

Unconjugated

Gene

Pttg1

Gene Alias

AW555095; C87862; EAP1; Esp1-associated protein; ESP1-associated protein 1; HPTTG; MGC126883; MGC138276; Pituitary tumor transforming; pituitary tumor-transforming 1; pituitary tumor-transforming gene 1; pituitary tumor-transforming gene 1 protein; PTTG; PTTG1; Pttg3; Securin; tumor-transforming protein 1; TUTR1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

9232

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation
  • It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC
  • The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors
  • The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression
  • It also contains a destruction box (D box) that is required for its degradation by the APC
  • The acidic C-terminal region of the encoded protein can act as a transactivation domain
  • The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus.

Compare Similar Items

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Img

Thermo Scientific

PIMA541255

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Antigen:
Securin

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
O95997

Gene Symbols:
Pttg1

Immunogen:
Recombinant protein within C-terminal Human Securin

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
JB37-37

Conjugate:
Unconjugated

Gene:
Pttg1

Gene Alias:
AW555095; C87862; EAP1; Esp1-associated protein; ESP1-associated protein 1; HPTTG; MGC126883; MGC138276; Pituitary tumor transforming; pituitary tumor-transforming 1; pituitary tumor-transforming gene 1; pituitary tumor-transforming gene 1 protein; PTTG; PTTG1; Pttg3; Securin; tumor-transforming protein 1; TUTR1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9232

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA541256

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Antigen:
Huntingtin

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P42858, P42859, P51111

Gene Symbols:
Htt

Immunogen:
Synthetic peptide within N-terminal Human Huntingtin

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
JB89-34

Conjugate:
Unconjugated

Gene:
Htt

Gene Alias:
AI256365; C430023I11Rik; Hd; HD protein; HD protein homolog; Hdh; HTT; Huntingtin; huntingtin (Huntington disease); Huntingtin, myristoylated N-terminal fragment; Huntington disease gene homolog; huntington disease protein; huntington disease protein homolog; IT15; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
15194, 29424, 3064

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA541257

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Antigen:
FKBP5

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q13451

Gene Symbols:
FKBP5

Immunogen:
Synthetic peptide within human FKBP51 aa 400-440

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
JB95-39

Conjugate:
Unconjugated

Gene:
FKBP5

Gene Alias:
51 kDa FK506-binding protein; 51 kDa FKBP; 54 kDa progesterone receptor-associated immunophilin; AIG6; androgen-regulated protein 6; D17Ertd592e; Dit1; EC 5.2.1.8; FF1 antigen; FK506 binding protein 5; FK506-binding protein 5; FKBP prolyl isomerase 5; Fkbp5; FKBP-5; FKBP51; FKBP-51; FKBP54; HSP90-binding immunophilin; p54; peptidylprolyl cis-trans isomerase; Peptidyl-prolyl cis-trans isomerase FKBP5; PPIase; PPIase FKBP5; Ptg-10; rotamase; T-cell FK506-binding protein

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2289, 361810

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA541262

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Antigen:
Phospho-CDK2 (Tyr15)

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P24941, P97377, Q63699

Gene Symbols:
CDK2

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Tyr15 of human Cdk2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
SN72-04

Conjugate:
Unconjugated

Gene:
CDK2

Gene Alias:
A630093N05Rik; CDC28; CDC2A; cdc2-related protein kinase; CDK1; CDK2; CDKN2; Cell division protein kinase 2; cyclin dependent kinase 2; cyclin dependent kinase 2-alpha; cyclin-dependent kinase 2; EC 2.7.11.22; EC 2.7.11.23; kinase Cdc2; MPF; p33 protein kinase; p33(CDK2); p33CDK2; p34 protein kinase

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1017, 12566, 362817

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid