PIMA541256

Huntingtin Recombinant Rabbit Monoclonal Antibody (JB89-34), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA541256-Each-of-1 In Stock ₹ 44,961.78

PIMA541256 - Each of 1

₹ 44,961.78

In Stock

Quantity

1

Base Price: ₹ 44,961.78

GST (18%): ₹ 8,093.12

Total Price: ₹ 53,054.90

Antigen

Huntingtin

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

P42858, P42859, P51111

Gene Symbols

Htt

Immunogen

Synthetic peptide within N-terminal Human Huntingtin

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

JB89-34

Conjugate

Unconjugated

Gene

Htt

Gene Alias

AI256365; C430023I11Rik; Hd; HD protein; HD protein homolog; Hdh; HTT; Huntingtin; huntingtin (Huntington disease); Huntingtin, myristoylated N-terminal fragment; Huntington disease gene homolog; huntington disease protein; huntington disease protein homolog; IT15; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

15194, 29424, 3064

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Huntingtin is a disease gene linked to Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons
  • This is thought to be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product
  • HD is a mid-life onset autosomal dominant neurodegenerative disease that is characterized by psychiatric disorders, dementia, and involuntary movements (chorea), leading to death in 10-20 years.The huntingtin locus is large, spanning 180 kb and consisting of 67 exons
  • The huntingtin gene is widely expressed and is required for normal development
  • It is expressed as 2 alternatively polyadenylated forms displaying different relative abundance in various fetal and adult tissues
  • The larger transcript is approximately 13.7 kb and is expressed predominantly in adult and fetal brain whereas the smaller transcript of approximately 10.3 kb is more widely expressed
  • The genetic defect leading to Huntington's disease may not necessarily eliminate transcription, but may confer a new property on the mRNA or alter the function of the protein.

Compare Similar Items

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Img

Thermo Scientific

PIMA541256

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Antigen:
Huntingtin

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P42858, P42859, P51111

Gene Symbols:
Htt

Immunogen:
Synthetic peptide within N-terminal Human Huntingtin

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
JB89-34

Conjugate:
Unconjugated

Gene:
Htt

Gene Alias:
AI256365; C430023I11Rik; Hd; HD protein; HD protein homolog; Hdh; HTT; Huntingtin; huntingtin (Huntington disease); Huntingtin, myristoylated N-terminal fragment; Huntington disease gene homolog; huntington disease protein; huntington disease protein homolog; IT15; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
15194, 29424, 3064

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA541257

--


Antigen:
FKBP5

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q13451

Gene Symbols:
FKBP5

Immunogen:
Synthetic peptide within human FKBP51 aa 400-440

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
JB95-39

Conjugate:
Unconjugated

Gene:
FKBP5

Gene Alias:
51 kDa FK506-binding protein; 51 kDa FKBP; 54 kDa progesterone receptor-associated immunophilin; AIG6; androgen-regulated protein 6; D17Ertd592e; Dit1; EC 5.2.1.8; FF1 antigen; FK506 binding protein 5; FK506-binding protein 5; FKBP prolyl isomerase 5; Fkbp5; FKBP-5; FKBP51; FKBP-51; FKBP54; HSP90-binding immunophilin; p54; peptidylprolyl cis-trans isomerase; Peptidyl-prolyl cis-trans isomerase FKBP5; PPIase; PPIase FKBP5; Ptg-10; rotamase; T-cell FK506-binding protein

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2289, 361810

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA541262

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Antigen:
Phospho-CDK2 (Tyr15)

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P24941, P97377, Q63699

Gene Symbols:
CDK2

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Tyr15 of human Cdk2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
SN72-04

Conjugate:
Unconjugated

Gene:
CDK2

Gene Alias:
A630093N05Rik; CDC28; CDC2A; cdc2-related protein kinase; CDK1; CDK2; CDKN2; Cell division protein kinase 2; cyclin dependent kinase 2; cyclin dependent kinase 2-alpha; cyclin-dependent kinase 2; EC 2.7.11.22; EC 2.7.11.23; kinase Cdc2; MPF; p33 protein kinase; p33(CDK2); p33CDK2; p34 protein kinase

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1017, 12566, 362817

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA541263

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Antigen:
eIF4A3

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P38919, Q3B8Q2, Q91VC3

Gene Symbols:
EIF4A3

Immunogen:
Recombinant protein within N-terminal Human eIF4A3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
JG35-33

Conjugate:
Unconjugated

Gene:
EIF4A3

Gene Alias:
2400003O03Rik; ATP-dependent RNA helicase DDX48; ATP-dependent RNA helicase eIF4A-3; Ddx48; DEAD (Asp-Glu-Ala-Asp) box polypeptide 48; DEAD box protein 48; Eif4a3; eIF4AIII; eIF-4A-III; eIF4A-III; eukaryotic initiation factor 4AIII; Eukaryotic initiation factor 4A-III; Eukaryotic initiation factor 4A-III, N-terminally processed; Eukaryotic initiation factor 4A-III-like protein; eukaryotic initiation factor 4A-like NUK-34; eukaryotic translation initiation factor 4A; Eukaryotic translation initiation factor 4A isoform 3; eukaryotic translation initiation factor 4A, isoform 3; eukaryotic translation initiation factor 4A3; hNMP 265; KIAA0111; mKIAA0111; MUK34; NMP 265; NMP265; Nuclear matrix protein 265; NUK34; RCPS; similar to DEAD (Asp-Glu-Ala-Asp) box polypeptide 48; zgc:56139

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
192170, 688288, 9775

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid