PIMA541566

Apolipoprotein J Monoclonal Antibody (D18), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA541566-Each-of-1 In Stock ₹ 46,844.10

PIMA541566 - Each of 1

₹ 46,844.10

In Stock

Quantity

1

Base Price: ₹ 46,844.10

GST (18%): ₹ 8,431.938

Total Price: ₹ 55,276.038

Antigen

Apolipoprotein J

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

Q29549

Gene Symbols

Clu

Immunogen

Recombinant protein Clusterin. The antigen corresponds to amino acid range 229-446 of the target protein.

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Porcine

Product Type

Antibody

Isotype

IgG1 κ

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

D18

Conjugate

Unconjugated

Gene

Clu

Gene Alias

AAG4; Aging associated protein 4; Aging-associated gene 4 protein; aging-associated protein 4; AI893575; apo j; Apo J a; Apo J alpha; Apo J b; Apo J beta; Apo J a; Apo J β; Apo Ja; Apo Jb; ApoJ; Apo-J; ApoJ a; ApoJ alpha; ApoJ b; ApoJ beta; ApoJ a; ApoJ β; ApoJa; ApoJalpha; ApoJb; ApoJbeta; Apolipoprotein J; CLI; Clu; CLU1; CLU2; clusterin; Clusterin alpha / beta chain; Clusterin alpha chain; Clusterin beta chain; Clustrin; Complement associated protein SP40; complement cytolysis inhibitor; Complement cytolysis inhibitor a chain; Complement cytolysis inhibitor b chain; complement lysis inhibitor; complement-associated protein SP-40,40; D14Ucla3; DAG; Dimeric acid glycoprotein; GP80; HGNC:2095; ku70-binding protein 1; Ku70-binding protein 1 (KUB1); KUB1; MGC24903; Msgp-2; NA1/NA2; RATTRPM2B; SGP2; Sgp-2; SP40; SP-40; Sugp-2; sulfated glycoprotein 2; Sulfated glycoprotein 2 (SGP2); testosterone repressed prostate message; testosterone repressed prostate message 2; Testosterone

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

397025

Content And Storage

-20°C

Form

Liquid

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Description

  • Isoform 1 functions as extracellular chaperone that prevents aggregation of nonnative proteins
  • Prevents stress-induced aggregation of blood plasma proteins
  • Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro)
  • Does not require ATP
  • Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70
  • Does not refold proteins by itself
  • Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysosomal or proteasomal degradation
  • Secreted isoform 1 protects cells against apoptosis and against cytolysis by complement
  • Intracellular isoforms interact with ubiquitin and SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes and promote the ubiquitination and subsequent proteasomal degradation of target proteins
  • Promotes proteasomal degradation of COMMD1 and IKBKB
  • Modulates NF-kappa-B transcriptional activity
  • Nuclear isoforms promote apoptosis
  • Mitochondrial isoforms suppress BAX-dependent release of cytochrome c into the cytoplasm and inhibit apoptosis
  • Plays a role in the regulation of cell proliferation.

Compare Similar Items

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Img

Thermo Scientific

PIMA541566

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Antigen:
Apolipoprotein J

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q29549

Gene Symbols:
Clu

Immunogen:
Recombinant protein Clusterin. The antigen corresponds to amino acid range 229-446 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Porcine

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
D18

Conjugate:
Unconjugated

Gene:
Clu

Gene Alias:
AAG4; Aging associated protein 4; Aging-associated gene 4 protein; aging-associated protein 4; AI893575; apo j; Apo J a; Apo J alpha; Apo J b; Apo J beta; Apo J a; Apo J β; Apo Ja; Apo Jb; ApoJ; Apo-J; ApoJ a; ApoJ alpha; ApoJ b; ApoJ beta; ApoJ a; ApoJ β; ApoJa; ApoJalpha; ApoJb; ApoJbeta; Apolipoprotein J; CLI; Clu; CLU1; CLU2; clusterin; Clusterin alpha / beta chain; Clusterin alpha chain; Clusterin beta chain; Clustrin; Complement associated protein SP40; complement cytolysis inhibitor; Complement cytolysis inhibitor a chain; Complement cytolysis inhibitor b chain; complement lysis inhibitor; complement-associated protein SP-40,40; D14Ucla3; DAG; Dimeric acid glycoprotein; GP80; HGNC:2095; ku70-binding protein 1; Ku70-binding protein 1 (KUB1); KUB1; MGC24903; Msgp-2; NA1/NA2; RATTRPM2B; SGP2; Sgp-2; SP40; SP-40; Sugp-2; sulfated glycoprotein 2; Sulfated glycoprotein 2 (SGP2); testosterone repressed prostate message; testosterone repressed prostate message 2; Testosterone

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
397025

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA541571

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Antigen:
COL8A1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P27658

Gene Symbols:
COL8A1

Immunogen:
Recombinant protein Collagen Type VIII Alpha 1. The antigen corresponds to amino acid range 575-743 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Western Blot

Clone:
C3

Conjugate:
Unconjugated

Gene:
COL8A1

Gene Alias:
C3orf7; cell proliferation-inducing protein 41; Col8a1; Col8a-1; Collagen alpha-1(VIII) chain; collagen type VIII alpha 1; collagen VIII, alpha-1 polypeptide; collagen, type VIII, alpha 1; endothelial collagen; procollagen type VIII alpha 1; procollagen, type VIII, alpha 1; smag-64; smooth muscle cell-expressed and macrophage conditioned medium-induced protein smag-64; Vastatin

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
1295

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA541575

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Antigen:
Cyclophilin A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P62937

Gene Symbols:
Ppia

Immunogen:
Recombinant protein Cyclophilin A. The antigen corresponds to amino acid range 2-165 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
C1

Conjugate:
Unconjugated

Gene:
Ppia

Gene Alias:
2700098C05; Cphn; CYCA; cyclophilin; Cyclophilin A; Cyclosporin A-binding protein; CyP A; CyP-18; CYPA; CyP-A; CYPH; EC 5.2.1.8; epididymis secretory sperm binding protein Li 69p; HEL-S-69p; HGNC:9253; I79_011869; MGC117158; MGC12404; MGC23397; p1B15; p31; Peptidyl-prolyl cis-trans isomerase A; Peptidyl-prolyl cis-trans isomerase A, N-terminally processed; peptidylprolyl isomerase A; peptidylprolyl isomerase A (cyclophilin A); PPIA; PPIase; PPIase A; rotamase; rotamase A; SP18; T cell cyclophilin

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
5478

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA541580

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Antigen:
PLA2G4A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P47712

Gene Symbols:
PLA2G4A

Immunogen:
Recombinant protein Cytosolic Phospholipase A2. The antigen corresponds to amino acid range 1-178 of the target protein.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C19

Conjugate:
Unconjugated

Gene:
PLA2G4A

Gene Alias:
calcium-dependent phospholipid-binding protein; Cpla2; cPLA2alpha; cPLA2-alpha; cytosolic group IVA; Cytosolic phospholipase A2; group IVA; lysophospholipase; MGC126350; Phosphatidylcholine 2-acylhydrolase; Phospholipase A2; phospholipase A2 cytosolic; phospholipase A2 group IVA; phospholipase A2, group IVA (cytosolic, calcium-dependent); Pla2c; Pla2g4; PLA2G4A

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
5321

Content And Storage:
-20°C

Form:
Liquid