PIMA542359
Phospho-GRK2 (Ser670) Recombinant Rabbit Monoclonal Antibody (HL1035), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA542359-Each-of-1 | In Stock | ₹ 44,020.62 |
PIMA542359 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,020.62
GST (18%): ₹ 7,923.712
Total Price: ₹ 51,944.332
Antigen
Phospho-GRK2 (Ser670)
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
P25098, Q99MK8
Gene Symbols
GRK2
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GRK2 (phospho Ser670).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
HL1035
Conjugate
Unconjugated
Gene
GRK2
Gene Alias
ADRBK1; Adrbk-1; adrenergic beta receptor kinase 1; adrenergic receptor kinase, beta 1; adrenergic, beta, receptor kinase 1; BARK; BARK1; Bark-1; beta ARK; Beta-adrenergic receptor kinase 1; beta-adrenergic receptor kinase 1 beta ARK1; beta-AR kinase-1; betaARK1; BETA-ARK1; beta-ARK-1; EC 2.7.1.126; G protein-coupled receptor kinase 2; G-protein coupled receptor kinase 2; G-protein-coupled receptor kinase 2; grk 2; Grk2; GRK-2
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
110355, 156
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Store as concentrated solution
- Centrifuge briefly prior to opening vial
- For short-term storage (1-2 weeks), store at 4°C
- For long-term storage, aliquot and store at -20°C or below
- Avoid multiple freeze-thaw cycles
- ADRBK1 (GRK2) is a serine/threonine kinase
- Many of the G protein-coupled receptors are known to be phosphorylated by G protein-dependent receptor kinases (GRKs)
- G protein-coupled receptor kinases (GRKs) are important regulators of G protein-coupled receptors(GPCRs)
- GRK2 (83 kDa), one of six members of this family that have been identified, is ubiquitously expressed in mammals
- After binding to their ligand and interacting with heterotrimeric G proteins, GPCRs (e.g., a2-adrenergic receptor) are phosphorylated by GRKs
- Internalization of the GPCRs, regulated by beta-arrestin-1, leads to activation of the Ras - Raf - ERK1&2 signaling pathway
- GRK2 activity is tightly controlled by different mechanisms including phosphorylation by kinases such as PKC, Src and ERK1&2, as well as interaction with various proteins
- ERK phosphorylates and thus inactivates GRK2 on serine 670 in a negative feedback mechanism.
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Antigen: Phospho-GRK2 (Ser670)
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P25098, Q99MK8
Gene Symbols: GRK2
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GRK2 (phospho Ser670).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: HL1035
Conjugate: Unconjugated
Gene: GRK2
Gene Alias: ADRBK1; Adrbk-1; adrenergic beta receptor kinase 1; adrenergic receptor kinase, beta 1; adrenergic, beta, receptor kinase 1; BARK; BARK1; Bark-1; beta ARK; Beta-adrenergic receptor kinase 1; beta-adrenergic receptor kinase 1 beta ARK1; beta-AR kinase-1; betaARK1; BETA-ARK1; beta-ARK-1; EC 2.7.1.126; G protein-coupled receptor kinase 2; G-protein coupled receptor kinase 2; G-protein-coupled receptor kinase 2; grk 2; Grk2; GRK-2
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 110355, 156
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Phospho-GRK2 (Ser670)
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P25098, Q99MK8
Gene Symbols:
GRK2
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GRK2 (phospho Ser670).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
HL1035
Conjugate:
Unconjugated
Gene:
GRK2
Gene Alias:
ADRBK1; Adrbk-1; adrenergic beta receptor kinase 1; adrenergic receptor kinase, beta 1; adrenergic, beta, receptor kinase 1; BARK; BARK1; Bark-1; beta ARK; Beta-adrenergic receptor kinase 1; beta-adrenergic receptor kinase 1 beta ARK1; beta-AR kinase-1; betaARK1; BETA-ARK1; beta-ARK-1; EC 2.7.1.126; G protein-coupled receptor kinase 2; G-protein coupled receptor kinase 2; G-protein-coupled receptor kinase 2; grk 2; Grk2; GRK-2
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
110355, 156
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Hepatitis D virus
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: __
Gene Symbols: __
Immunogen: Full length Hepatitis D virus Large data + Small delta recombinant protein. (Hepatitis delta virus genotype I (isolate D380)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Virus
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: HL1053
Conjugate: Unconjugated
Gene: __
Gene Alias: HDV; Hepatitis Delta Virus
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Hepatitis D virus
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Full length Hepatitis D virus Large data + Small delta recombinant protein. (Hepatitis delta virus genotype I (isolate D380)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
HL1053
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
HDV; Hepatitis Delta Virus
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Hepatitis D virus
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: __
Gene Symbols: __
Immunogen: Full length Hepatitis D virus Large data + Small delta recombinant protein. (Hepatitis delta virus genotype I (isolate D380)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Virus
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: HL1055
Conjugate: Unconjugated
Gene: __
Gene Alias: HDV; Hepatitis Delta Virus
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Hepatitis D virus
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Full length Hepatitis D virus Large data + Small delta recombinant protein. (Hepatitis delta virus genotype I (isolate D380)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
HL1055
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
HDV; Hepatitis Delta Virus
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Hepatitis D Virus Large delta Protein
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: __
Gene Symbols: __
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of Hepatitis D virus Large delta protein (Hepatitis delta virus genotype I (isolate D380). The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Virus
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: HL1051
Conjugate: Unconjugated
Gene: __
Gene Alias: HDV
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Hepatitis D Virus Large delta Protein
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of Hepatitis D virus Large delta protein (Hepatitis delta virus genotype I (isolate D380). The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
HL1051
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
HDV
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid