PIMA542681

PAI1 Recombinant Rabbit Monoclonal Antibody (6L6Y7), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA542681-Each-of-1 In Stock ₹ 44,020.62

PIMA542681 - Each of 1

₹ 44,020.62

In Stock

Quantity

1

Base Price: ₹ 44,020.62

GST (18%): ₹ 7,923.712

Total Price: ₹ 51,944.332

Antigen

PAI1

Classification

Recombinant Monoclonal

Concentration

1.3 mg/mL

Formulation

PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P05121

Gene Symbols

Serpine1

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PAI-1/Serpin E1 (P05121).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Clone

6L6Y7

Conjugate

Unconjugated

Gene

Serpine1

Gene Alias

Endothelial plasminogen activator inhibitor; nexin, plasminogen activator inhibitor type 1; PAI; PAI1; PAI-1; PAI1 protein; PAI1A; Pai1aa; Planh; Planh1; plas; plasminogen activator inhibitor; plasminogen activator inhibitor 1; plasminogen activator inhibitor I; plasminogen activator inhibitor, type I; plasminogen activator inhibitor-1; Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI); putative plasminogen activator inhibitor-1; RATPAI1A; serine (or cysteine) peptidase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; serine (or cysteine) proteinase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, member 1; serpin E1; serpin family E member 1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; SERPINE1; SERPINE-1

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5054

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Related Products

Img

Thermo Scientific

PIMA537889

--

Img

Thermo Scientific

PIMA537842

--

Img

Thermo Scientific

PIMA543585

--

Img

Thermo Scientific

PIMA543957

--

Img

Thermo Scientific

PIMA542680

--

Img

Thermo Scientific

PIMA542597

--

Img

Thermo Scientific

PIMA542502

--

Img

Thermo Scientific

PIMA537841

--

Description

  • Positive test controls include: HepG2
  • The target is usually found in the following locations: Secreted
  • Immunogen sequence: SKDRNVVFSP YGVASVLAML QLTTGGETQQ QIQAAMGFKI DDKGMAPALR HLYKELMGPW NKDEISTTDA IFVQRDLKLV QGFMPHFFRL FRSTVKQVDF S PAI1 (plasminogen activator inhibitor 1) belongs to serine protease inhibitor superfamily, and is the principal inhibitor of tissue-type and urokinase-type plasminogen activators (tPA and uPA)
  • Platelets are the main source of the circulating PAI11, but it is synthesized and secreted by many tissue and cell types, including fibroblasts, smooth muscle cells, endothelial cells, hepatocytes, and inflammatory cells
  • Expression of PAI11 can be regulated at the transcriptional level by many factors including growth factors, cytokines, hormones, inflammatory factors, glucose or lipid metabolites, vascular tone regulating factors, chemicals, and other environmental or physical factors
  • PAI1 is present at increased levels in various disease states, and has been linked to an increased occurrence of thrombosis in obesity, thrombophilia and the metabolic syndrome
  • Defects in PAI-1 are characterized by abnormal bleeding
  • PAI1 mediates inhibition of fibrinolysis by inhibiting the activity of plasminogen activator, and may promote neuronal survival
  • Other defects in PAI1 are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency)
  • Alternatively spliced transcript variants encoding different isoforms of PAI1 have been found.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA542681

--


Antigen:
PAI1

Classification:
Recombinant Monoclonal

Concentration:
1.3 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P05121

Gene Symbols:
Serpine1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PAI-1/Serpin E1 (P05121).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
6L6Y7

Conjugate:
Unconjugated

Gene:
Serpine1

Gene Alias:
Endothelial plasminogen activator inhibitor; nexin, plasminogen activator inhibitor type 1; PAI; PAI1; PAI-1; PAI1 protein; PAI1A; Pai1aa; Planh; Planh1; plas; plasminogen activator inhibitor; plasminogen activator inhibitor 1; plasminogen activator inhibitor I; plasminogen activator inhibitor, type I; plasminogen activator inhibitor-1; Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI); putative plasminogen activator inhibitor-1; RATPAI1A; serine (or cysteine) peptidase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; serine (or cysteine) proteinase inhibitor, clade E, member 1; serine (or cysteine) proteinase inhibitor, member 1; serpin E1; serpin family E member 1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; SERPINE1; SERPINE-1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5054

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA542684

--


Antigen:
SMAD2

Classification:
Recombinant Monoclonal

Concentration:
0.95 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O70436, Q15796, Q62432

Gene Symbols:
SMAD2

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Smad2 (Q15796).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
2E3D8

Conjugate:
Unconjugated

Gene:
SMAD2

Gene Alias:
7120426M23Rik; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; Smad2; Smad-2; Smad2Deltaexon3

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17126, 29357, 4087

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA542687

--


Antigen:
LPP

Classification:
Recombinant Monoclonal

Concentration:
0.33 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q5XI07, Q8BFW7, Q93052

Gene Symbols:
LPP

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LPP (Q93052).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
8M2R8

Conjugate:
Unconjugated

Gene:
LPP

Gene Alias:
9430020K16Rik; AA959454; AU024130; B130055L10Rik; C79715; D630048H16; I79_000864; LIM domain containing preferred translocation partner in lipoma; LIM domain-containing preferred translocation partner in lipoma; LIM protein; lipoma preferred partner; Lipoma-preferred partner; Lipoma-preferred partner homolog; Lipoma-preferred-partner; LPP

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
210126, 288010, 4026

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA542691

--


Antigen:
MYH7B

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
A2AQP0

Gene Symbols:
MYH7B

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1750-1983 of human MYH7B (NP_0659353)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
7W8J3

Conjugate:
Unconjugated

Gene:
MYH7B

Gene Alias:
__

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
311570, 668940

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid