PIMA542821
COX2 Recombinant Rabbit Monoclonal Antibody (2V7G8), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA542821-Each-of-1 | In Stock | ₹ 44,020.62 |
PIMA542821 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,020.62
GST (18%): ₹ 7,923.712
Total Price: ₹ 51,944.332
Antigen
COX2
Classification
Recombinant Monoclonal
Concentration
0.8 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P35354, Q05769
Gene Symbols
PTGS2
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 505-604 of human COX2/PTGS2 (P35354).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
2V7G8
Conjugate
Unconjugated
Gene
PTGS2
Gene Alias
COII; COX2; Cox-2; COXII; cyclooxygenase; cyclooxygenase 2; cyclooxygenase 2b; cyclooxygenase-2; Cytochrome c oxidase polypeptide II; Cytochrome c oxidase subunit 2; cytochrome c oxidase subunit II; glucocorticoid-regulated inflammatory cyclooxygenase; Gripghs; hCox-2; Macrophage activation-associated marker protein P71/73; mitochondrially encoded cytochrome c oxidase II; MTCO2; MT-CO2; PES-2; PGG/HS; PGH synthase 2; Pghs2; PGHS-2; Pghs-b; PHS II; PHS-2; prostaglandin G/H synthase 2; Prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); Ptgs2; Tis10; TIS10 protein
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
19225, 5743
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Positive test controls include: HeLa, RAW264.7, Rat brain
- Immunogen sequence: GETMVEVGAP FSLKGLMGNV ICSPAYWKPS TFGGEVGFQI INTASIQSLI CNNVKGCPFT SFSVPDPELI KTVTINASSS RSGLDDINPT VLLKERSTEL COX2 converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis, including production of inflammatory prostaglandins
- The conversion of arachidonate to prostaglandin H2 is a 2 step reaction: a cyclooxygenase (COX) reaction which converts arachidonate to prostaglandin G2 (PGG2) and a peroxidase reaction in which PGG2 is reduced to prostaglandin H2 (PGH2)
- It is constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and is up-regulated under pathological conditions, such as in cancer and inflammation (in contrast to the iso-enzyme PTGS1, which is expressed ubiquitously)
- Up-regulation of COX2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis
- In cancer cells, COX2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis
- COX2 is naturally inhibited by calcitriol (the active form of Vitamin D)
- Glucocorticoids chronically trans-repress PTGS2 gene activity in vivo in part by interfering with transcription initiation and elongation
- COX2 is a target of NSAID such as aspirin, which can reduce pain and swelling from inflammation driven by COX2.
Compare Similar Items
Show Difference
Antigen: COX2
Classification: Recombinant Monoclonal
Concentration: 0.8 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P35354, Q05769
Gene Symbols: PTGS2
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 505-604 of human COX2/PTGS2 (P35354).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 2V7G8
Conjugate: Unconjugated
Gene: PTGS2
Gene Alias: COII; COX2; Cox-2; COXII; cyclooxygenase; cyclooxygenase 2; cyclooxygenase 2b; cyclooxygenase-2; Cytochrome c oxidase polypeptide II; Cytochrome c oxidase subunit 2; cytochrome c oxidase subunit II; glucocorticoid-regulated inflammatory cyclooxygenase; Gripghs; hCox-2; Macrophage activation-associated marker protein P71/73; mitochondrially encoded cytochrome c oxidase II; MTCO2; MT-CO2; PES-2; PGG/HS; PGH synthase 2; Pghs2; PGHS-2; Pghs-b; PHS II; PHS-2; prostaglandin G/H synthase 2; Prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); Ptgs2; Tis10; TIS10 protein
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19225, 5743
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
COX2
Classification:
Recombinant Monoclonal
Concentration:
0.8 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P35354, Q05769
Gene Symbols:
PTGS2
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 505-604 of human COX2/PTGS2 (P35354).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
2V7G8
Conjugate:
Unconjugated
Gene:
PTGS2
Gene Alias:
COII; COX2; Cox-2; COXII; cyclooxygenase; cyclooxygenase 2; cyclooxygenase 2b; cyclooxygenase-2; Cytochrome c oxidase polypeptide II; Cytochrome c oxidase subunit 2; cytochrome c oxidase subunit II; glucocorticoid-regulated inflammatory cyclooxygenase; Gripghs; hCox-2; Macrophage activation-associated marker protein P71/73; mitochondrially encoded cytochrome c oxidase II; MTCO2; MT-CO2; PES-2; PGG/HS; PGH synthase 2; Pghs2; PGHS-2; Pghs-b; PHS II; PHS-2; prostaglandin G/H synthase 2; Prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); Ptgs2; Tis10; TIS10 protein
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19225, 5743
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: RCOR1
Classification: Recombinant Monoclonal
Concentration: 1.15 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q8CFE3, Q9UKL0
Gene Symbols: RCOR1
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CoREST/RCOR1 (Q9UKL0).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: ChIP Assay, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 9B3R7
Conjugate: Unconjugated
Gene: RCOR1
Gene Alias: 5730409O11; 6720480E22Rik; AU042633; COREST; D12Wsu95e; im:6904264; KIAA0071; LOC102554884; mKIAA0071; Protein CoREST; RCOR; Rcor1; REST corepressor 1; REST corepressor 1-like; Rocr1; si:dkey-46n18.7; zgc:158607
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 102554884, 217864, 23186
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
RCOR1
Classification:
Recombinant Monoclonal
Concentration:
1.15 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q8CFE3, Q9UKL0
Gene Symbols:
RCOR1
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CoREST/RCOR1 (Q9UKL0).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
ChIP Assay, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
9B3R7
Conjugate:
Unconjugated
Gene:
RCOR1
Gene Alias:
5730409O11; 6720480E22Rik; AU042633; COREST; D12Wsu95e; im:6904264; KIAA0071; LOC102554884; mKIAA0071; Protein CoREST; RCOR; Rcor1; REST corepressor 1; REST corepressor 1-like; Rocr1; si:dkey-46n18.7; zgc:158607
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
102554884, 217864, 23186
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: HDAC6
Classification: Recombinant Monoclonal
Concentration: 1.15 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q9UBN7
Gene Symbols: HDAC6
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HDAC6 (Q9UBN7).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 9V1W2
Conjugate: Unconjugated
Gene: HDAC6
Gene Alias: CPBHM; FLJ16239; Hd6; HDA6; Hdac5; Hdac6; histone deacetylase 5; histone deacetylase 6; Histone deacetylase mHDA2; JM21; KIAA0901; mHDA2; PPP1R90; protein phosphatase 1, regulatory subunit 90; scurfy candidate 6; Sfc6
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10013
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
HDAC6
Classification:
Recombinant Monoclonal
Concentration:
1.15 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q9UBN7
Gene Symbols:
HDAC6
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HDAC6 (Q9UBN7).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
9V1W2
Conjugate:
Unconjugated
Gene:
HDAC6
Gene Alias:
CPBHM; FLJ16239; Hd6; HDA6; Hdac5; Hdac6; histone deacetylase 5; histone deacetylase 6; Histone deacetylase mHDA2; JM21; KIAA0901; mHDA2; PPP1R90; protein phosphatase 1, regulatory subunit 90; scurfy candidate 6; Sfc6
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10013
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: MAGOH
Classification: Recombinant Monoclonal
Concentration: 2.15 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P61326, P61327, Q27W02
Gene Symbols: MAGOH
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 67-146 of human MAGOH (P61326).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: 3J7K2
Conjugate: Unconjugated
Gene: MAGOH
Gene Alias: ch211-216k22.5; hypothetical protein LOC550395; mago homolog, exon junction complex core component; mago homolog, exon junction complex subunit; mago nashi; Magoh; MAGOH1; MAGOHA; Mago-m; mago-nashi homolog, proliferation-associated; mago-nashi homolog, proliferation-associated (Drosophila); mago-nashi-like proliferation-associated protein; Mos2; Protein mago nashi homolog; RP5-1024G6.4; zgc:112220
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17149, 298385, 4116
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
MAGOH
Classification:
Recombinant Monoclonal
Concentration:
2.15 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P61326, P61327, Q27W02
Gene Symbols:
MAGOH
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 67-146 of human MAGOH (P61326).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
3J7K2
Conjugate:
Unconjugated
Gene:
MAGOH
Gene Alias:
ch211-216k22.5; hypothetical protein LOC550395; mago homolog, exon junction complex core component; mago homolog, exon junction complex subunit; mago nashi; Magoh; MAGOH1; MAGOHA; Mago-m; mago-nashi homolog, proliferation-associated; mago-nashi homolog, proliferation-associated (Drosophila); mago-nashi-like proliferation-associated protein; Mos2; Protein mago nashi homolog; RP5-1024G6.4; zgc:112220
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17149, 298385, 4116
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid