PIMA542837
iNOS Recombinant Rabbit Monoclonal Antibody (3L0U6), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA542837-Each-of-1 | In Stock | ₹ 44,020.62 |
PIMA542837 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,020.62
GST (18%): ₹ 7,923.712
Total Price: ₹ 51,944.332
Antigen
iNOS
Classification
Recombinant Monoclonal
Concentration
3 mg/mL
Formulation
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P29477, Q06518
Gene Symbols
Nos2
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 2-200 of human iNOS (P35228).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot
Clone
3L0U6
Conjugate
Unconjugated
Gene
Nos2
Gene Alias
Hepatocyte NOS; hepatocytes; HEP-NOS; inducible nitric oxide synthase; inducible NO synthase; Inducible NOS; iNos; i-NOS; Inosl; MAC-NOS; macrophage NOS; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; nitric oxide synthase-inducible; NOS; NOS type II; NOS, type II; Nos2; Nos-2; Nos2a; NOS-II; OTTMUSP00000000202; peptidyl-cysteine S-nitrosylase NOS2
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18126, 24599
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Positive test controls include: RAW264.7
- Immunogen sequence: ACPWKFLFKT KFHQYAMNGE KDINNNVEKA PCATSSPVTQ DDLQYHNLSK QQNESPQPLV ETGKKSPESL VKLDATPLSS PRHVRIKNWG SGMTFQDTLH HKAKGILTCR SKSCLGSIMT PKSLTRGPRD KPTPPDELLP QAIEFVNQYY GSFKEAKIEE HLARVEAVTK EIETTGTYQL TGDELIFATK QAWRNAPRC iNOS (Inducible Nitric oxide, NO, NOS) is an inorganic, gaseous free radical that carries a variety of messages between cells
- Vasorelaxation, neurotransmission and cytotoxicity can all be potentiated through cellular response to NO
- NO production is mediated by members of the nitric oxide synthase (NOS) family
- iNOS is expressed in liver and inducible by a combination of lipopolysaccharide and certain cytokines
- NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO
- Two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) and endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II), have been cloned
- All NOS isoforms contain calmodulin, nicotinamide adenine dinucleotide phosphate (NADPH), flavin adenine dinucleotide (FAD), and flavin mononucleotide (FMN) binding domains
- iNOS is found in a variety of cell types including macrophages, hepatocytes, synoviocytes, and smooth muscle cells
- Cytokines such as interferon-gamma (IFN), tumor necrosis factor (TNF), interleukin-1 and -2, and lipopolysaccarides (LPS) cause an increase in iNOS mRNA, protein, and activity levels
- Protein kinase C-stimulating agents exhibit the same effect on iNOS activity
- After cytokine induction, iNOS exhibits a delayed activity response which is then followed by a significant increase in NO production over a long period of time
- Three related iNOS pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17
- Diseases associated with iNOS dysfunction include achalasia and impotence.
Compare Similar Items
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Antigen: iNOS
Classification: Recombinant Monoclonal
Concentration: 3 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P29477, Q06518
Gene Symbols: Nos2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 2-200 of human iNOS (P35228).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Clone: 3L0U6
Conjugate: Unconjugated
Gene: Nos2
Gene Alias: Hepatocyte NOS; hepatocytes; HEP-NOS; inducible nitric oxide synthase; inducible NO synthase; Inducible NOS; iNos; i-NOS; Inosl; MAC-NOS; macrophage NOS; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; nitric oxide synthase-inducible; NOS; NOS type II; NOS, type II; Nos2; Nos-2; Nos2a; NOS-II; OTTMUSP00000000202; peptidyl-cysteine S-nitrosylase NOS2
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18126, 24599
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
iNOS
Classification:
Recombinant Monoclonal
Concentration:
3 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P29477, Q06518
Gene Symbols:
Nos2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 2-200 of human iNOS (P35228).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Clone:
3L0U6
Conjugate:
Unconjugated
Gene:
Nos2
Gene Alias:
Hepatocyte NOS; hepatocytes; HEP-NOS; inducible nitric oxide synthase; inducible NO synthase; Inducible NOS; iNos; i-NOS; Inosl; MAC-NOS; macrophage NOS; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; nitric oxide synthase-inducible; NOS; NOS type II; NOS, type II; Nos2; Nos-2; Nos2a; NOS-II; OTTMUSP00000000202; peptidyl-cysteine S-nitrosylase NOS2
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18126, 24599
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: TCP1
Classification: Recombinant Monoclonal
Concentration: 0.27 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P17987
Gene Symbols: TCP1
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TCP1 alpha (P17987).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 3G9G8
Conjugate: Unconjugated
Gene: TCP1
Gene Alias: 65 kDa antigen; AI528772; c-cpn; CCT; Cct1; Ccta; CCTalpha; CCT-alpha; chaperonin-containing T-complex alpha subunit TCP1; chaperonin-containing T-complex polypeptide alpha subunit; cytosolic chaperonin containing t-complex polypeptide 1; D6S230E; hypothetical protein; p63; tailless complex polypeptide 1; tailless complex polypeptide 1A; Tailless complex polypeptide 1B; t-complex 1; t-complex polypeptide 1; t-complex protein 1; T-complex protein 1 alpha subunit-like protein; T-complex protein 1 subunit alpha; T-complex protein 1 subunit alpha A; T-complex protein 1 subunit alpha B; T-complex protein 1, alpha subunit; Tcp1; Tcp-1; TCP-1-A; TCP-1-alpha; TCP-1-B; Tp63; TRic; Unknown (protein for MGC:133746); YD8142.13; YD8142B.04; YDR212W
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6950
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
TCP1
Classification:
Recombinant Monoclonal
Concentration:
0.27 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P17987
Gene Symbols:
TCP1
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TCP1 alpha (P17987).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
3G9G8
Conjugate:
Unconjugated
Gene:
TCP1
Gene Alias:
65 kDa antigen; AI528772; c-cpn; CCT; Cct1; Ccta; CCTalpha; CCT-alpha; chaperonin-containing T-complex alpha subunit TCP1; chaperonin-containing T-complex polypeptide alpha subunit; cytosolic chaperonin containing t-complex polypeptide 1; D6S230E; hypothetical protein; p63; tailless complex polypeptide 1; tailless complex polypeptide 1A; Tailless complex polypeptide 1B; t-complex 1; t-complex polypeptide 1; t-complex protein 1; T-complex protein 1 alpha subunit-like protein; T-complex protein 1 subunit alpha; T-complex protein 1 subunit alpha A; T-complex protein 1 subunit alpha B; T-complex protein 1, alpha subunit; Tcp1; Tcp-1; TCP-1-A; TCP-1-alpha; TCP-1-B; Tp63; TRic; Unknown (protein for MGC:133746); YD8142.13; YD8142B.04; YDR212W
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6950
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: ODC1
Classification: Recombinant Monoclonal
Concentration: 3 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P11926
Gene Symbols: Odc1
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ODC1 (P11926).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: 5R7V10
Conjugate: Unconjugated
Gene: Odc1
Gene Alias: MGC103389; Odc; ODC1; Ornithine decarboxylase; ornithine decarboxylase 1; ornithine decarboxylase, structural 1; Ornitine decarboxylase
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4953
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
ODC1
Classification:
Recombinant Monoclonal
Concentration:
3 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P11926
Gene Symbols:
Odc1
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ODC1 (P11926).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
5R7V10
Conjugate:
Unconjugated
Gene:
Odc1
Gene Alias:
MGC103389; Odc; ODC1; Ornithine decarboxylase; ornithine decarboxylase 1; ornithine decarboxylase, structural 1; Ornitine decarboxylase
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4953
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: SIRT2
Classification: Recombinant Monoclonal
Concentration: 0.36 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q8IXJ6
Gene Symbols: SIRT2
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SIRT2 (Q8IXJ6).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: 1E1U3
Conjugate: Unconjugated
Gene: SIRT2
Gene Alias: 5730427M03Rik; 5E5 antigen; mSIR2L2; NAD-dependent deacetylase sirtuin-2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; silent information regulator 2; silent mating type information regulation 2, (S.cerevisiae, homolog)-like; sirtuin 2; SIR2; SIR2L; SIR2L2; SIR2-like protein 2; sir2-related protein type 2; Sirt2; sirtuin 2; sirtuin type 2; sirtuin-2
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22933
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
SIRT2
Classification:
Recombinant Monoclonal
Concentration:
0.36 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q8IXJ6
Gene Symbols:
SIRT2
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SIRT2 (Q8IXJ6).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
1E1U3
Conjugate:
Unconjugated
Gene:
SIRT2
Gene Alias:
5730427M03Rik; 5E5 antigen; mSIR2L2; NAD-dependent deacetylase sirtuin-2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; silent information regulator 2; silent mating type information regulation 2, (S.cerevisiae, homolog)-like; sirtuin 2; SIR2; SIR2L; SIR2L2; SIR2-like protein 2; sir2-related protein type 2; Sirt2; sirtuin 2; sirtuin type 2; sirtuin-2
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22933
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid