PIMA542831

RAP1GAP Recombinant Rabbit Monoclonal Antibody (8V9I6), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA542831-Each-of-1 In Stock ₹ 44,020.62

PIMA542831 - Each of 1

₹ 44,020.62

In Stock

Quantity

1

Base Price: ₹ 44,020.62

GST (18%): ₹ 7,923.712

Total Price: ₹ 51,944.332

Antigen

RAP1GAP

Classification

Recombinant Monoclonal

Concentration

0.66 mg/mL

Formulation

PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

A2ALS5, P47736

Gene Symbols

RAP1GAP

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Rap1GAP (P47736).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Western Blot

Clone

8V9I6

Conjugate

Unconjugated

Gene

RAP1GAP

Gene Alias

1300019I11Rik; 2310004O14Rik; AI427470; ARPP-90; KIAA0474; RAP1 GTPase activating protein; Rap1 GTPase-activating protein; rap1 GTPase-activating protein 1; Rap1, GTPase-activating protein 1; Rap1ga1; Rap1GAP; Rap1GAP1; RAP1GAPII; RAPGAP

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

110351, 313644, 5909

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Positive test controls include: BxPC-3, U-87MG, Mouse brain, Rat brain
  • The target is usually found in the following locations: Golgi apparatus membrane, Peripheral membrane protein
  • Immunogen sequence: MIEKMQGSRM DEQRCSFPPP LKTEEDYIPY PSVHEVLGRE GPFPLILLPQ FGGYWIEGTN HEITSIPETE PLQSPTTKVK LECNPTARIY RKHFLGKEHF Rap1GAP specifically stimulates GTP hydrolytic activity of the monomeric G protein Rap1
  • Physical interaction between G alpha z, a member of the Gi family of trimeric G proteins, and Rap1GAP blocks the ability of regulators of G protein signaling to stimulate GTP hydrolysis of the alpha subunit, and also attenuates the ability of activated G alpha z to inhibit adenylyl cyclase
  • Rap1GAP is expressed in the brain, kidney and pancreas and may act as a signal integrator to coordinate and/or integrate Gz signaling and Rap1 signaling in cells
  • A novel isoform of Rapl GTPase-activating protein, designated Rap1GAPII, binds specifically to G alpha z
  • Stimulation of the Gi-coupled M2 Muscarinic receptor translocates Rap1GAPII from the cytosol to the membrane and decreases the amount of GTP-bound Rap1, resulting in the activation of ERK/MAPK.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA542831

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Antigen:
RAP1GAP

Classification:
Recombinant Monoclonal

Concentration:
0.66 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
A2ALS5, P47736

Gene Symbols:
RAP1GAP

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Rap1GAP (P47736).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
8V9I6

Conjugate:
Unconjugated

Gene:
RAP1GAP

Gene Alias:
1300019I11Rik; 2310004O14Rik; AI427470; ARPP-90; KIAA0474; RAP1 GTPase activating protein; Rap1 GTPase-activating protein; rap1 GTPase-activating protein 1; Rap1, GTPase-activating protein 1; Rap1ga1; Rap1GAP; Rap1GAP1; RAP1GAPII; RAPGAP

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
110351, 313644, 5909

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA542833

--


Antigen:
CD35

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P17927

Gene Symbols:
CR1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1940-2039 of human CD35/CR1 (P17927).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
2A0Q1

Conjugate:
Unconjugated

Gene:
CR1

Gene Alias:
C3 binding protein; C3b/C4b receptor; C3-binding protein; C3BR; C4BR; CD35; CD35 antigen; complement component (3b/4b) receptor 1 (Knops blood group); Complement Component (3b/4b) receptor 1 including Knops blood group system; complement component 3b/4b receptor 1 (Knops blood group); complement receptor type 1; CR1; KN; Knops blood group antigen

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1378

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA542835

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Antigen:
SUV39H2

Classification:
Recombinant Monoclonal

Concentration:
1.25 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9H5I1

Gene Symbols:
SUV39H2

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 311-410 of human KMT1B / SUV39H2 (Q9H5I1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
6L2D9

Conjugate:
Unconjugated

Gene:
SUV39H2

Gene Alias:
4930507K23Rik; AA536750; D030054H19Rik; D2Ertd544e; FLJ23414; H3 K9 HMTase 2; H3-K9-HMTase 2; Histone H3-K9 methyltransferase 2; histone-lysine N-methyltransferase SUV39H2; KMT1; KMT1B; lysine N-methyltransferase 1B; RP11-2K17.2; Su; Su(var)3-9 homolog 2; suppressor of variegation 3-9 homolog 2; suppressor of variegation 3-9 homolog 2 (Drosophila); Suv39h histone methyltransferase; Suv39h2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79723

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA542837

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Antigen:
iNOS

Classification:
Recombinant Monoclonal

Concentration:
3 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P29477, Q06518

Gene Symbols:
Nos2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 2-200 of human iNOS (P35228).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
3L0U6

Conjugate:
Unconjugated

Gene:
Nos2

Gene Alias:
Hepatocyte NOS; hepatocytes; HEP-NOS; inducible nitric oxide synthase; inducible NO synthase; Inducible NOS; iNos; i-NOS; Inosl; MAC-NOS; macrophage NOS; nitric oxide synthase 2; nitric oxide synthase 2, inducible; nitric oxide synthase 2, inducible, macrophage; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, inducible; nitric oxide synthase, macrophage; nitric oxide synthase-inducible; NOS; NOS type II; NOS, type II; Nos2; Nos-2; Nos2a; NOS-II; OTTMUSP00000000202; peptidyl-cysteine S-nitrosylase NOS2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18126, 24599

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid