PIMA543073
ErbB3 Chimeric Recombinant Human Monoclonal Antibody (mhA24), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA543073-Each-of-1 | In Stock | ₹ 44,020.62 |
PIMA543073 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,020.62
GST (18%): ₹ 7,923.712
Total Price: ₹ 51,944.332
Antigen
ErbB3 Chimeric
Classification
Recombinant Monoclonal
Concentration
1.53 mg/mL
Formulation
arginine, histidine with 0.02% Tween 80, 120mM NaCl and no preservative
Gene Accession No.
P21860
Gene Symbols
ERBB3
Immunogen
Recombinant Human HER3/ErbB3 protein.
Quantity
200 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1 κ
Applications
Neutralization
Clone
mhA24
Conjugate
Unconjugated
Gene
ERBB3
Gene Alias
avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
Host Species
Human
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
2065
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Specificity: Human HER3/ErbB3
- This product is a chimeric monoclonal antibody combining the constant domains of the human IgG1 molecule with mouse variable regions
- The antibody was produced using recombinant antibody technology
- ErbB3 (c-erbB-3/HER-3) is a member of the type I family of growth factor receptors and binds to ligands in the heregulin family
- ErbB3 is over-expressed in a variety of tumors in the prostate, bladder, breast, stomach, pancreas, and colon
- Heregulin and EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents
- The ErbB3 gene is located on the long arm of human chromosome 12 (12q13) and is transcribed into a 6
- 2kb mRNA which is translated into a 160/180 kDa glycoprotein
- The ErbB3 gene encodes a transmembrane receptor tyrosine kinase due to alternative splicing and forms heterodimers with other EGF receptor family members that have kinase activity
- Heterodimerization leads to the activation of pathways that lead to cell proliferation or differentiation
- Alternate transcriptional splice variants encoding different isoforms of ErbB3 have been characterized
- One ErbB3 isoform lacks the intermembrane region, is secreted outside the cell, and acts to modulate the activity of the membrane-bound form
- Additional splice variants have also been reported, but they have not been thoroughly characterized.
Compare Similar Items
Show Difference
Antigen: ErbB3 Chimeric
Classification: Recombinant Monoclonal
Concentration: 1.53 mg/mL
Formulation: arginine, histidine with 0.02% Tween 80, 120mM NaCl and no preservative
Gene Accession No.: P21860
Gene Symbols: ERBB3
Immunogen: Recombinant Human HER3/ErbB3 protein.
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Applications: Neutralization
Clone: mhA24
Conjugate: Unconjugated
Gene: ERBB3
Gene Alias: avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
Host Species: Human
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 2065
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
ErbB3 Chimeric
Classification:
Recombinant Monoclonal
Concentration:
1.53 mg/mL
Formulation:
arginine, histidine with 0.02% Tween 80, 120mM NaCl and no preservative
Gene Accession No.:
P21860
Gene Symbols:
ERBB3
Immunogen:
Recombinant Human HER3/ErbB3 protein.
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Neutralization
Clone:
mhA24
Conjugate:
Unconjugated
Gene:
ERBB3
Gene Alias:
avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
Host Species:
Human
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
2065
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: CD74
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: P04233
Gene Symbols: CD74
Immunogen: Recombinant Human CD74 protein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA
Clone: 301
Conjugate: Unconjugated
Gene: CD74
Gene Alias: CD74; CD74 antigen; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); CD74 molecule; Cd74 molecule, major histocompatibility complex, class II invariant chain; class II-associated invariant chain peptide; CLIP; DHLAG; dinucleotide microsatellite; gamma chain of class II antigens; H-2 class II histocompatibility antigen gamma chain; histocompatibility: class II antigens, gamma chain of; HLA class II histocompatibility antigen gamma chain; HLADG; HLA-DR antigens-associated invariant chain; HLA-DR-gamma; ia antigen-associated invariant chain; Ia-associated invariant chain; Ia-GAMMA; Ii; invariant polypeptide of major histocompatibility complex, class II antigen-associated; INVG34; MHC class II-associated invariant chain; MHC HLA-DR gamma chain; p33
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 972
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
CD74
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
P04233
Gene Symbols:
CD74
Immunogen:
Recombinant Human CD74 protein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA
Clone:
301
Conjugate:
Unconjugated
Gene:
CD74
Gene Alias:
CD74; CD74 antigen; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); CD74 molecule; Cd74 molecule, major histocompatibility complex, class II invariant chain; class II-associated invariant chain peptide; CLIP; DHLAG; dinucleotide microsatellite; gamma chain of class II antigens; H-2 class II histocompatibility antigen gamma chain; histocompatibility: class II antigens, gamma chain of; HLA class II histocompatibility antigen gamma chain; HLADG; HLA-DR antigens-associated invariant chain; HLA-DR-gamma; ia antigen-associated invariant chain; Ia-associated invariant chain; Ia-GAMMA; Ii; invariant polypeptide of major histocompatibility complex, class II antigen-associated; INVG34; MHC class II-associated invariant chain; MHC HLA-DR gamma chain; p33
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
972
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: PD-1
Classification: Recombinant Monoclonal
Concentration: 5.2 mg/mL
Formulation: arginine, histidine with 0.02% Tween 80, 120mM NaCl and no preservative
Gene Accession No.: Q15116
Gene Symbols: Pdcd1
Immunogen: Recombinant Human PD1/PDCD1/CD279 Protein.
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG4
Applications: Neutralization
Clone: HF06
Conjugate: Unconjugated
Gene: Pdcd1
Gene Alias: CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2
Host Species: Human
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5133
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
PD-1
Classification:
Recombinant Monoclonal
Concentration:
5.2 mg/mL
Formulation:
arginine, histidine with 0.02% Tween 80, 120mM NaCl and no preservative
Gene Accession No.:
Q15116
Gene Symbols:
Pdcd1
Immunogen:
Recombinant Human PD1/PDCD1/CD279 Protein.
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG4
Applications:
Neutralization
Clone:
HF06
Conjugate:
Unconjugated
Gene:
Pdcd1
Gene Alias:
CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2
Host Species:
Human
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5133
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: PD-1
Classification: Recombinant Monoclonal
Concentration: 5.08 mg/mL
Formulation: arginine, histidine with 0.02% Tween 80, 120mM NaCl and no preservative
Gene Accession No.: Q15116
Gene Symbols: Pdcd1
Immunogen: Recombinant Human PD1/PDCD1/CD279 Protein.
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG4
Applications: Neutralization
Clone: HN94
Conjugate: Unconjugated
Gene: Pdcd1
Gene Alias: CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2
Host Species: Human
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5133
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
PD-1
Classification:
Recombinant Monoclonal
Concentration:
5.08 mg/mL
Formulation:
arginine, histidine with 0.02% Tween 80, 120mM NaCl and no preservative
Gene Accession No.:
Q15116
Gene Symbols:
Pdcd1
Immunogen:
Recombinant Human PD1/PDCD1/CD279 Protein.
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG4
Applications:
Neutralization
Clone:
HN94
Conjugate:
Unconjugated
Gene:
Pdcd1
Gene Alias:
CD279; EGK_05005; hPD1; hPD-1; hPD-l; hSLE1; Ly101; mPD-1; PD1; PD-1; Pdc1; Pdcd1; programmed cell death 1; programmed cell death 1 protein; programmed cell death protein 1; programmed cell death protein 1-like; programmed death 1; Protein PD1; protein PD-1; sCD279; SLEB2; soluble CD279; systemic lupus erythematosus susceptibility 2
Host Species:
Human
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5133
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid