PIMA543119

IL-23 p19 Chimeric Recombinant Human Monoclonal Antibody (mh066), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA543119-Each-of-1 In Stock ₹ 44,020.62

PIMA543119 - Each of 1

₹ 44,020.62

In Stock

Quantity

1

Base Price: ₹ 44,020.62

GST (18%): ₹ 7,923.712

Total Price: ₹ 51,944.332

Antigen

IL-23 p19 Chimeric

Classification

Recombinant Monoclonal

Concentration

2.25 mg/mL

Formulation

arginine, histidine with 0.02% Tween 80, 120mM NaCl and no preservative

Gene Accession No.

Q9EQ14, Q9NPF7

Gene Symbols

IL23A

Immunogen

Recombinant Human IL23A and Mouse IL12B Heterodimer Protein.

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1 κ

Applications

Neutralization

Clone

mh066

Conjugate

Unconjugated

Gene

IL23A

Gene Alias

il 23; IL 23 A; IL12B; Il-12b; Il12p40; Il-12p40; il23; IL-23; IL-23 subunit alpha; IL23A; IL-23A; IL-23-A; IL23P19; IL-23p19; ILN; Interleukin; interleukin 12B; interleukin 23 p19 subunit; interleukin 23 subunit alpha; interleukin 23, alpha subunit p19; interleukin-23 subunit alpha; Interleukin-23 subunit p19; interleukin-six, G-CSF related factor; JKA3 induced upon T-cell activation; MGC79388; P19; p40; RP23-388G23.1; SGRF; UNQ2498/PRO5798

Host Species

Human

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

51561, 83430

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Related Products

Img

Thermo Scientific

PIMA543118

--

Img

Thermo Scientific

PIMA543738

--

Img

Thermo Scientific

PIMA542748

--

Img

Thermo Scientific

PIMA543743

--

Img

Thermo Scientific

PIMA543745

--

Img

Thermo Scientific

PIMA544053

--

Img

Thermo Scientific

PIMA543693

--

Img

Thermo Scientific

PIMA542656

--

Description

  • Specificity: Human IL23A and Human IL12B Heterodimer
  • This product is a chimeric monoclonal antibody combining the constant domains of the human IgG1 molecule with mouse variable regions
  • The antibody was produced using recombinant antibody technology
  • IL-23 is a heterodimeric cytokine composed of the p40 subunit of IL-12 disulfide-linked with a protein p19
  • p19, like p35 of IL-12, is biologically inactive by itself
  • IL-23 interacts with IL-12Rbeta1 and an additional, novel beta2-like receptor subunit with STAT4 binding domain, termed IL-23R
  • IL-23 is secreted by activated mouse and human dendritic cells
  • Biological activities of mouse IL-23 are distinct from those of mouse IL-12
  • Mouse IL-23 was found not to induce significant amounts of IFN-γ
  • Mouse IL-23 does induce strong proliferation of memory T cells (but not naive T cells), whereas IL-12 has no effect on memory cells
  • Additionally, mouse IL-23 (but not IL-12) can activate mouse memory T cells to produce the proinflammatory cytokine IL-17
  • Human IL-23 has biological properties which are less distinct from human IL-12; human IL-23 induces proliferation of memory T cells and induces moderate levels of IFN-γ production by naive and memory T cells, as compared to IL-12.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA543119

--


Antigen:
IL-23 p19 Chimeric

Classification:
Recombinant Monoclonal

Concentration:
2.25 mg/mL

Formulation:
arginine, histidine with 0.02% Tween 80, 120mM NaCl and no preservative

Gene Accession No.:
Q9EQ14, Q9NPF7

Gene Symbols:
IL23A

Immunogen:
Recombinant Human IL23A and Mouse IL12B Heterodimer Protein.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Neutralization

Clone:
mh066

Conjugate:
Unconjugated

Gene:
IL23A

Gene Alias:
il 23; IL 23 A; IL12B; Il-12b; Il12p40; Il-12p40; il23; IL-23; IL-23 subunit alpha; IL23A; IL-23A; IL-23-A; IL23P19; IL-23p19; ILN; Interleukin; interleukin 12B; interleukin 23 p19 subunit; interleukin 23 subunit alpha; interleukin 23, alpha subunit p19; interleukin-23 subunit alpha; Interleukin-23 subunit p19; interleukin-six, G-CSF related factor; JKA3 induced upon T-cell activation; MGC79388; P19; p40; RP23-388G23.1; SGRF; UNQ2498/PRO5798

Host Species:
Human

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
51561, 83430

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

PIMA543120

--


Antigen:
GP130

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q00560

Gene Symbols:
IL6ST

Immunogen:
Recombinant Mouse gp130/CD130/IL6ST protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA

Clone:
230

Conjugate:
Unconjugated

Gene:
IL6ST

Gene Alias:
5133400A03Rik; AA389424; Ac1055; BB405851; CD130; CD130 antigen; CDW130; D13Ertd699e; EGK_16499; Gp130; gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form; gp130, oncostatin M receptor; GP130-RAPS; IL-6; IL-6 receptor subunit beta; IL-6R subunit beta; IL-6RB; IL-6R-beta; IL6R-beta; IL6ST; interleukin 6 signal transducer; interleukin 6 signal transducer (gp130, oncostatin M receptor); interleukin 6 signal transducer receptor; interleukin receptor beta chain; interleukin-6 receptor subunit beta; Interleukin-6 signal transducer; interleukin-6 signal transducer receptor; membrane glycoprotein; membrane glycoprotein 130; membrane glycoprotein gp130; oncostatin-M receptor subunit alpha

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
16195

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA543121

--


Antigen:
RSV Fusion Protein

Classification:
Recombinant Monoclonal

Concentration:
6.13 mg/mL

Formulation:
arginine, histidine with no preservative

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Recombinant Human respiratory syncytial virus (RSV) Fusion glycoprotein/RSV-F protein.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Virus

Product Type:
Antibody

Isotype:
IgG

Applications:
Neutralization, Western Blot

Clone:
R338

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
human respiratory syncytial virus; RSV; RSV Fusion protein; Rsvgp08

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Fischer Scientific

PIMA543122

--


Antigen:
Layilin

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q6UX15

Gene Symbols:
LAYN

Immunogen:
Recombinant Human Layilin protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA

Clone:
107

Conjugate:
Unconjugated

Gene:
LAYN

Gene Alias:
E030012M19Rik; FLJ30977; FLJ31092; Gm511; layilin; LAYN; LYAN; RGD1564444; UNQ208/PRO234

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
143903

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid