PIMA543745

IL-1 alpha Monoclonal Antibody (3#), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA543745-Each-of-1 In Stock ₹ 17,017.88

PIMA543745 - Each of 1

₹ 17,017.88

In Stock

Quantity

1

Base Price: ₹ 17,017.88

GST (18%): ₹ 3,063.218

Total Price: ₹ 20,081.098

Antigen

IL-1 alpha

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

P01583

Gene Symbols

Il1a

Immunogen

Recombinant protein Interleukin 1 Alpha. The antigen corresponds to amino acid range 113-271 of the target protein.

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2b κ

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

3#

Conjugate

Unconjugated

Gene

Il1a

Gene Alias

CTLA8; hematopoietin-1; IL 1 a; IL 1a; IL1; IL-1 alpha; IL17; IL1A; Il-1a; IL-1alpha; IL1-ALPHA; IL1F1; IL1a; ILN; Interleukin; interleukin 1 alpha; interleukin 1, alpha; interleukin 17; interleukin 1a; interleukin 1-alpha; interleukin 1-alpha (AA 1 - 152); Interleukin1 alpha; interleukin-1 alpha; interleukin-1 alpha precursor; Interleukin-17A; preinterleukin 1 alpha; pre-interleukin-1 alpha; pro-interleukin-1-alpha; RP23-160G19.8

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

3552

Content And Storage

-20°C

Form

Liquid

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Description

  • IL-1 alpha (Interleukin-1 alpha) is a proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells
  • IL-1 alpha is coded by the IL1A gene and signals through two receptors, IL-1RI and IL-1RII, both of which are shared with IL-1 beta
  • IL1A is located on the q arm on chromosome 2 at position 13
  • IL-1 alpha plays an important role in innate host defense by triggering the production of other proinflammatory cytokines in target cells and initiating acute-phase responses
  • IL-1 alpha activity can be moderated by IL-1 Receptor Antagonist (IL-1RA), a protein produced by many cell types that blocks receptor binding through competitive inhibition
  • IL-1 alpha is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis
  • Further, IL-1 alpha is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury and induces apoptosis
  • The IL1A gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2
  • IL1 alpha regulates the activities of NF-kappaB and mitogen-activated protein kinases
  • IL-1 alpha can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO)
  • High levels of IL-1 alpha are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Compare Similar Items

Show Difference

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Thermo Scientific

PIMA543745

--


Antigen:
IL-1 alpha

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P01583

Gene Symbols:
Il1a

Immunogen:
Recombinant protein Interleukin 1 Alpha. The antigen corresponds to amino acid range 113-271 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
3#

Conjugate:
Unconjugated

Gene:
Il1a

Gene Alias:
CTLA8; hematopoietin-1; IL 1 a; IL 1a; IL1; IL-1 alpha; IL17; IL1A; Il-1a; IL-1alpha; IL1-ALPHA; IL1F1; IL1a; ILN; Interleukin; interleukin 1 alpha; interleukin 1, alpha; interleukin 17; interleukin 1a; interleukin 1-alpha; interleukin 1-alpha (AA 1 - 152); Interleukin1 alpha; interleukin-1 alpha; interleukin-1 alpha precursor; Interleukin-17A; preinterleukin 1 alpha; pre-interleukin-1 alpha; pro-interleukin-1-alpha; RP23-160G19.8

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
3552

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA543747

--


Antigen:
IGF1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P05019

Gene Symbols:
IGF1

Immunogen:
Recombinant protein Insulin Like Growth Factor 1. The antigen corresponds to amino acid range 49-118 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Immunocytochemistry, Western Blot

Clone:
C1

Conjugate:
Unconjugated

Gene:
IGF1

Gene Alias:
C730016P09Rik; class 1 insulin-like growth factor I preproprotein; class 2 insulin-like growth factor I preproprotein; H-IGF-1; IBP1; IGF; IGF1; Igf-1; IGF1A; IGFI; Igf-I; IGFIa; IGF-IA; IGF-IB; insulin growth factor-1; Insulin like growth factor; insulin like growth factor 1; insulin-like growth factor 1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor I; insulin-like growth factor I (somatomedin C); insulin-like growth factor IB; mechano growth factor; MGF; M-IGF-1; OTTHUMP00000195084; prepro-IGF-I; prepro-insulin-like growth factor I; R-IGF-1; somatomedin; Somatomedin C; Somatomedin-C

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
3479

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA543748

--


Antigen:
IGFBP4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P22692

Gene Symbols:
IGFBP4

Immunogen:
Recombinant protein Insulin Like Growth Factor Binding Protein 4. The antigen corresponds to amino acid range 22-258 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
A3

Conjugate:
Unconjugated

Gene:
IGFBP4

Gene Alias:
AI875747; Band 3A; BP-4; Deb2; differentially expressed in B16F10 2; HT29-IGFBP; IBP4; IBP-4; IGF-binding protein 4; IGFBP; Igfbp4; IGF-BP4; IGFBP-4; Insulin like growth factor binding protein; insulin like growth factor binding protein 4; insulin-like growth factor binding protein 4; insulin-like growth factor binding protein-4; insulin-like growth factor-binding protein 4; insulin-like growth factor-binding protein-4; LOW QUALITY PROTEIN: insulin-like growth factor-binding protein 4

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
3487

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA543749

--


Antigen:
IGFBP4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P22692

Gene Symbols:
IGFBP4

Immunogen:
Recombinant protein Insulin Like Growth Factor Binding Protein 4. The antigen corresponds to amino acid range 22-258 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C15

Conjugate:
Unconjugated

Gene:
IGFBP4

Gene Alias:
AI875747; Band 3A; BP-4; Deb2; differentially expressed in B16F10 2; HT29-IGFBP; IBP4; IBP-4; IGF-binding protein 4; IGFBP; Igfbp4; IGF-BP4; IGFBP-4; Insulin like growth factor binding protein; insulin like growth factor binding protein 4; insulin-like growth factor binding protein 4; insulin-like growth factor binding protein-4; insulin-like growth factor-binding protein 4; insulin-like growth factor-binding protein-4; LOW QUALITY PROTEIN: insulin-like growth factor-binding protein 4

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
3487

Content And Storage:
-20°C

Form:
Liquid