PIMA543955

Apolipoprotein J Monoclonal Antibody (C1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA543955-Each-of-1 In Stock ₹ 19,422.12

PIMA543955 - Each of 1

₹ 19,422.12

In Stock

Quantity

1

Base Price: ₹ 19,422.12

GST (18%): ₹ 3,495.982

Total Price: ₹ 22,918.102

Antigen

Apolipoprotein J

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

P05371

Gene Symbols

Clu

Immunogen

Recombinant protein Clusterin. The antigen corresponds to amino acid range 227-447 of the target protein.

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Rat

Product Type

Antibody

Isotype

IgG2a κ

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

C1

Conjugate

Unconjugated

Gene

Clu

Gene Alias

AAG4; Aging associated protein 4; Aging-associated gene 4 protein; aging-associated protein 4; AI893575; apo j; Apo J a; Apo J alpha; Apo J b; Apo J beta; Apo J a; Apo J β; Apo Ja; Apo Jb; ApoJ; Apo-J; ApoJ a; ApoJ alpha; ApoJ b; ApoJ beta; ApoJ a; ApoJ β; ApoJa; ApoJalpha; ApoJb; ApoJbeta; Apolipoprotein J; CLI; Clu; CLU1; CLU2; clusterin; Clusterin alpha / beta chain; Clusterin alpha chain; Clusterin beta chain; Clustrin; Complement associated protein SP40; complement cytolysis inhibitor; Complement cytolysis inhibitor a chain; Complement cytolysis inhibitor b chain; complement lysis inhibitor; complement-associated protein SP-40,40; D14Ucla3; DAG; Dimeric acid glycoprotein; GP80; HGNC:2095; ku70-binding protein 1; Ku70-binding protein 1 (KUB1); KUB1; MGC24903; Msgp-2; NA1/NA2; RATTRPM2B; SGP2; Sgp-2; SP40; SP-40; Sugp-2; sulfated glycoprotein 2; Sulfated glycoprotein 2 (SGP2); testosterone repressed prostate message; testosterone repressed prostate message 2; Testosterone

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

24854

Content And Storage

-20°C

Form

Liquid

Related Products

Img

Thermo Scientific

PIMA543985

--

Img

Thermo Scientific

PIMA537842

--

Img

Thermo Scientific

PIMA543994

--

Img

Thermo Scientific

PIMA543614

--

Img

Thermo Scientific

PIMA542354

--

Img

Thermo Scientific

PIMA537886

--

Img

Thermo Scientific

PIMA543638

--

Img

Thermo Scientific

PIMA543809

--

Description

  • Isoform 1 functions as extracellular chaperone that prevents aggregation of nonnative proteins
  • Prevents stress-induced aggregation of blood plasma proteins
  • Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro)
  • Does not require ATP
  • Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70
  • Does not refold proteins by itself
  • Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysosomal or proteasomal degradation
  • Secreted isoform 1 protects cells against apoptosis and against cytolysis by complement
  • Intracellular isoforms interact with ubiquitin and SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes and promote the ubiquitination and subsequent proteasomal degradation of target proteins
  • Promotes proteasomal degradation of COMMD1 and IKBKB
  • Modulates NF-kappa-B transcriptional activity
  • Nuclear isoforms promote apoptosis
  • Mitochondrial isoforms suppress BAX-dependent release of cytochrome c into the cytoplasm and inhibit apoptosis
  • Plays a role in the regulation of cell proliferation.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA543955

--


Antigen:
Apolipoprotein J

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P05371

Gene Symbols:
Clu

Immunogen:
Recombinant protein Clusterin. The antigen corresponds to amino acid range 227-447 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C1

Conjugate:
Unconjugated

Gene:
Clu

Gene Alias:
AAG4; Aging associated protein 4; Aging-associated gene 4 protein; aging-associated protein 4; AI893575; apo j; Apo J a; Apo J alpha; Apo J b; Apo J beta; Apo J a; Apo J β; Apo Ja; Apo Jb; ApoJ; Apo-J; ApoJ a; ApoJ alpha; ApoJ b; ApoJ beta; ApoJ a; ApoJ β; ApoJa; ApoJalpha; ApoJb; ApoJbeta; Apolipoprotein J; CLI; Clu; CLU1; CLU2; clusterin; Clusterin alpha / beta chain; Clusterin alpha chain; Clusterin beta chain; Clustrin; Complement associated protein SP40; complement cytolysis inhibitor; Complement cytolysis inhibitor a chain; Complement cytolysis inhibitor b chain; complement lysis inhibitor; complement-associated protein SP-40,40; D14Ucla3; DAG; Dimeric acid glycoprotein; GP80; HGNC:2095; ku70-binding protein 1; Ku70-binding protein 1 (KUB1); KUB1; MGC24903; Msgp-2; NA1/NA2; RATTRPM2B; SGP2; Sgp-2; SP40; SP-40; Sugp-2; sulfated glycoprotein 2; Sulfated glycoprotein 2 (SGP2); testosterone repressed prostate message; testosterone repressed prostate message 2; Testosterone

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
24854

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA543956

--


Antigen:
APOL2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q9BQE5

Gene Symbols:
APOL2

Immunogen:
Recombinant protein Apolipoprotein L2. The antigen corresponds to amino acid range 186-337 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
C1

Conjugate:
Unconjugated

Gene:
APOL2

Gene Alias:
Apol2; ApoL-2; APOL3; Apol8; APOL-II; apolipoprotein L 8; apolipoprotein L, 2; Apolipoprotein L2; Apolipoprotein L-2; apolipoprotein L-II; OTTHUMP00000028936

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
23780

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA543957

--


Antigen:
Antithrombin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P01008

Gene Symbols:
Serpinc1

Immunogen:
Recombinant protein Antithrombin. The antigen corresponds to amino acid range 33-464 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
C3

Conjugate:
Unconjugated

Gene:
Serpinc1

Gene Alias:
AI114908; antithrombin; Antithrombin 3; anti-thrombin 3; antithrombin III; antithrombin-III; AT3; At-3; AT3D; ATIII; hypothetical protein LOC540261; MGC22579; PRO0309; serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1; serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1; serpin C1; serpin family C member 1; serpin peptidase inhibitor clade C member 1; serpin peptidase inhibitor, clade C (antithrombin), member 1; serpin peptidase inhibitor, clade C, member 1; Serpinc1; THPH7

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
462

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA543958

--


Antigen:
Annexin V

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P08758

Gene Symbols:
Anxa5

Immunogen:
Recombinant protein Annexin V. The antigen corresponds to amino acid range 1-320 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
C13

Conjugate:
Unconjugated

Gene:
Anxa5

Gene Alias:
Anchorin CII; annexin 5; annexin A5; Annexin V; annexin-5; Anx5; ANXA5; Calphobindin I; CBP-I; Endonexin II; ENX2; epididymis secretory protein Li 7; HEL-S-7; LC5; lipocortin V; PAP-I; placental anticoagulant protein 4; Placental anticoagulant protein I; PP4; R74653; RPRGL3; Thromboplastin inhibitor; VAC-alpha; Vascular anticoagulant-alpha

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
308

Content And Storage:
-20°C

Form:
Liquid