PIMA543985

Apolipoprotein J Monoclonal Antibody (D18), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA543985-Each-of-1 In Stock ₹ 19,422.12

PIMA543985 - Each of 1

₹ 19,422.12

In Stock

Quantity

1

Base Price: ₹ 19,422.12

GST (18%): ₹ 3,495.982

Total Price: ₹ 22,918.102

Antigen

Apolipoprotein J

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

Q29549

Gene Symbols

Clu

Immunogen

Recombinant protein Clusterin. The antigen corresponds to amino acid range 229-446 of the target protein.

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Porcine

Product Type

Antibody

Isotype

IgG1 κ

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

D18

Conjugate

Unconjugated

Gene

Clu

Gene Alias

AAG4; Aging associated protein 4; Aging-associated gene 4 protein; aging-associated protein 4; AI893575; apo j; Apo J a; Apo J alpha; Apo J b; Apo J beta; Apo J a; Apo J β; Apo Ja; Apo Jb; ApoJ; Apo-J; ApoJ a; ApoJ alpha; ApoJ b; ApoJ beta; ApoJ a; ApoJ β; ApoJa; ApoJalpha; ApoJb; ApoJbeta; Apolipoprotein J; CLI; Clu; CLU1; CLU2; clusterin; Clusterin alpha / beta chain; Clusterin alpha chain; Clusterin beta chain; Clustrin; Complement associated protein SP40; complement cytolysis inhibitor; Complement cytolysis inhibitor a chain; Complement cytolysis inhibitor b chain; complement lysis inhibitor; complement-associated protein SP-40,40; D14Ucla3; DAG; Dimeric acid glycoprotein; GP80; HGNC:2095; ku70-binding protein 1; Ku70-binding protein 1 (KUB1); KUB1; MGC24903; Msgp-2; NA1/NA2; RATTRPM2B; SGP2; Sgp-2; SP40; SP-40; Sugp-2; sulfated glycoprotein 2; Sulfated glycoprotein 2 (SGP2); testosterone repressed prostate message; testosterone repressed prostate message 2; Testosterone

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

397025

Content And Storage

-20°C

Form

Liquid

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Description

  • Isoform 1 functions as extracellular chaperone that prevents aggregation of nonnative proteins
  • Prevents stress-induced aggregation of blood plasma proteins
  • Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro)
  • Does not require ATP
  • Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70
  • Does not refold proteins by itself
  • Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysosomal or proteasomal degradation
  • Secreted isoform 1 protects cells against apoptosis and against cytolysis by complement
  • Intracellular isoforms interact with ubiquitin and SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes and promote the ubiquitination and subsequent proteasomal degradation of target proteins
  • Promotes proteasomal degradation of COMMD1 and IKBKB
  • Modulates NF-kappa-B transcriptional activity
  • Nuclear isoforms promote apoptosis
  • Mitochondrial isoforms suppress BAX-dependent release of cytochrome c into the cytoplasm and inhibit apoptosis
  • Plays a role in the regulation of cell proliferation.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA543985

--


Antigen:
Apolipoprotein J

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q29549

Gene Symbols:
Clu

Immunogen:
Recombinant protein Clusterin. The antigen corresponds to amino acid range 229-446 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Porcine

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
D18

Conjugate:
Unconjugated

Gene:
Clu

Gene Alias:
AAG4; Aging associated protein 4; Aging-associated gene 4 protein; aging-associated protein 4; AI893575; apo j; Apo J a; Apo J alpha; Apo J b; Apo J beta; Apo J a; Apo J β; Apo Ja; Apo Jb; ApoJ; Apo-J; ApoJ a; ApoJ alpha; ApoJ b; ApoJ beta; ApoJ a; ApoJ β; ApoJa; ApoJalpha; ApoJb; ApoJbeta; Apolipoprotein J; CLI; Clu; CLU1; CLU2; clusterin; Clusterin alpha / beta chain; Clusterin alpha chain; Clusterin beta chain; Clustrin; Complement associated protein SP40; complement cytolysis inhibitor; Complement cytolysis inhibitor a chain; Complement cytolysis inhibitor b chain; complement lysis inhibitor; complement-associated protein SP-40,40; D14Ucla3; DAG; Dimeric acid glycoprotein; GP80; HGNC:2095; ku70-binding protein 1; Ku70-binding protein 1 (KUB1); KUB1; MGC24903; Msgp-2; NA1/NA2; RATTRPM2B; SGP2; Sgp-2; SP40; SP-40; Sugp-2; sulfated glycoprotein 2; Sulfated glycoprotein 2 (SGP2); testosterone repressed prostate message; testosterone repressed prostate message 2; Testosterone

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
397025

Content And Storage:
-20°C

Form:
Liquid

Img

Fischer Scientific

PIMA543986

--


Antigen:
ADAMTS9

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q9P2N4

Gene Symbols:
ADAMTS9

Immunogen:
Cys1727-Leu1935 (Accession Q9P2N4), with N-terminal His Tag

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Western Blot

Clone:
D2

Conjugate:
Unconjugated

Gene:
ADAMTS9

Gene Alias:
a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 9; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 9; ADAM metallopeptidase with thrombospondin type 1 motif, 9; ADAMs; ADAM-TS 9; ADAMTS9; JSCFDG; KIAA1312; metalloendopeptidases

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
56999

Content And Storage:
-20°C

Form:
Liquid

Img

Fischer Scientific

PIMA543987

--


Antigen:
ADAMTS9

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q9P2N4

Gene Symbols:
ADAMTS9

Immunogen:
Cys1727-Leu1935 (Accession Q9P2N4), with N-terminal His Tag

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Western Blot

Clone:
D2

Conjugate:
Unconjugated

Gene:
ADAMTS9

Gene Alias:
a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 9; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 9; ADAM metallopeptidase with thrombospondin type 1 motif, 9; ADAMs; ADAM-TS 9; ADAMTS9; JSCFDG; KIAA1312; metalloendopeptidases

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
56999

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA543988

--


Antigen:
ACVR2A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P27037

Gene Symbols:
ACVR2A

Immunogen:
Recombinant protein Activin A Receptor Type II A. The antigen corresponds to amino acid range 20-135 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
C11

Conjugate:
Unconjugated

Gene:
ACVR2A

Gene Alias:
activin A receptor type 2A; activin A receptor type IIA; activin A receptor, type IIA; activin receptor IIA; activin receptor type IIA; Activin receptor type-2A; Actrii; ActrIIa; ACTR-IIA; ACVR2; Acvr2a; rActR-II; TactrII; type II activin receptor

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
92

Content And Storage:
-20°C

Form:
Liquid