PIMA544026

CD2 Monoclonal Antibody (RM2-5), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA544026-Each-of-1 In Stock ₹ 22,716.18

PIMA544026 - Each of 1

₹ 22,716.18

In Stock

Quantity

1

Base Price: ₹ 22,716.18

GST (18%): ₹ 4,088.912

Total Price: ₹ 26,805.092

Antigen

CD2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 15mM sodium azide; pH 7.4

Gene Accession No.

P08920

Gene Symbols

CD2

Immunogen

murine thymocytes

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG2b λ

Applications

Flow Cytometry, Immunoprecipitation

Clone

RM2-5

Conjugate

Unconjugated

Gene

CD2

Gene Alias

Cd2; CD2 antigen; CD2 antigen (p50), sheep red blood cell receptor; CD2 molecule; CD2R; cluster of differentiation 2; Erythrocyte receptor; FLJ46032; LFA2; LFA-2; LFA-3 receptor; Ly37; Ly-37; lymphocyte antigen 37; OX34; OX-34; OX-34 antigen; OX-45 surface antigen homolog to human T lymphocyte CD2 antigen; Rosette receptor; SRBC; surface immunoglobulin superfamily molecule; T11; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5

Host Species

Rat

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

12481

Content And Storage

4° C, do not freeze

Form

Liquid

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Description

  • CD2 (LFA-2) is a monomeric surface antigen (MW range 45-58 kDa) of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells
  • CD2 is one of the earliest T-cell markers, being present on more than 95% of thymocytes and it is also found on some natural killer cells, but not on B lymphocytes
  • Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it
  • The interaction between CD2 and CD58 stabilizes adhesion between T cells and antigen presenting or target cells
  • Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion
  • Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58
  • Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion
  • CD2 deficiency reduces intestinal inflammation and helps to control infection
  • Diseases associated with CD2 dysfunction include penis squamous cell carcinoma and immune deficiency due to the absence of the thymus.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA544026

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Antigen:
CD2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P08920

Gene Symbols:
CD2

Immunogen:
murine thymocytes

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b λ

Applications:
Flow Cytometry, Immunoprecipitation

Clone:
RM2-5

Conjugate:
Unconjugated

Gene:
CD2

Gene Alias:
Cd2; CD2 antigen; CD2 antigen (p50), sheep red blood cell receptor; CD2 molecule; CD2R; cluster of differentiation 2; Erythrocyte receptor; FLJ46032; LFA2; LFA-2; LFA-3 receptor; Ly37; Ly-37; lymphocyte antigen 37; OX34; OX-34; OX-34 antigen; OX-45 surface antigen homolog to human T lymphocyte CD2 antigen; Rosette receptor; SRBC; surface immunoglobulin superfamily molecule; T11; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
12481

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

PIMA544027

--


Antigen:
CD42a

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P14770

Gene Symbols:
GP9

Immunogen:
Human acute lymphoblastic leukemia cells

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry

Clone:
GR-P

Conjugate:
Unconjugated

Gene:
GP9

Gene Alias:
CD42a; Glycoprotein 9; glycoprotein 9 (platelet); glycoprotein IX (platelet); glycoprotein IX platelet; GP9; GPIX; GP-IX; platelet glycoprotein IX; Platelet GPIX

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2815, 609630

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

PIMA544029

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Antigen:
CD178

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
P48023

Gene Symbols:
Faslg

Immunogen:
L5178Y mouse T lymphoma cells expressing recombinant human CD178

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
NOK-1

Conjugate:
Unconjugated

Gene:
Faslg

Gene Alias:
ADAM10-processed FasL form; ALPS1B; APL; Apoptosis (APO 1) antigen ligand 1; apoptosis (APO-1) antigen ligand 1; Apoptosis (APO-1) antigen ligand 1 (Fas antigen ligand); apoptosis antigen ligand; APT1LG1; APTL; CD178; CD178 antigen; CD95 ligand; CD95 ligand protein;Generalized lymphoproliferative disease (Gld); Cd95l; CD95-L; CD95L protein; fas antigen ligand; Fas ligand; Fas ligand (TNF superfamily, member 6); Fasl; Fas-L; FasL ICD; FasL intracellular domain; Faslg; Fas-LG; generalized lymphoproliferative disease; gld; mutant tumor necrosis factor family member 6; Receptor-binding FasL ectodomain; sFasL; Soluble Fas ligand; soluble form; SPA; SPPL2A-processed FasL form; TNFL; Tnfsf6; TNLG1A; Tumor necrosis factor (ligand) superfamily member 6; Tumor necrosis factor (ligand) superfamily member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Tumor necrosis factor (ligand) superfamily, member 6 (apoptosis (APO-1) antigen ligand 1) (Fas antigen ligand); Tumor necrosis factor ligand; tumor necrosis factor ligand 1A; tumor necrosis factor ligand superfamily member 6; Tumor necrosis factor ligand superfamily member 6 (TNFL6 / TNFSF6); Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
356

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

PIMA544030

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Antigen:
CD41

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide; pH 7.4

Gene Accession No.:
Q9QUM0

Gene Symbols:
Itga2b

Immunogen:
Murine platelets

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation

Clone:
MWReg30

Conjugate:
Unconjugated

Gene:
Itga2b

Gene Alias:
AI172977; alpha IIb; alphaIIb; alphaIIb protein; BDPLT16; BDPLT2; CD41; CD41B; form 1; form 2; GP IIb; GP2B; GPalpha IIb; GPIIb; GT; GTA; HPA3; integrin alpha 2b; integrin alpha 2b (Cd41b); integrin alpha-IIb; Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2; integrin subunit alpha 2b; integrin subunit alpha IIb; integrin, alpha 2B; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); ITGA2B; ITGAB; platelet fibrinogen receptor, alpha subunit; platelet glycoprotein IIb; platelet glycoprotein IIb of IIb/II Ia complex; platelet glycoprotein IIb of IIb/IIIa complex; platelet membrane glycoprotein IIb; platelet-specific antigen BAK; PPP1R93; protein phosphatase 1, regulatory subunit 93

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
16399

Content And Storage:
4° C, do not freeze

Form:
Liquid