PIMA544450

SMAD2 Recombinant Rabbit Monoclonal Antibody (BLR130H), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA544450-Each-of-1 In Stock ₹ 13,492.81

PIMA544450 - Each of 1

₹ 13,492.81

In Stock

Quantity

1

Base Price: ₹ 13,492.81

GST (18%): ₹ 2,428.706

Total Price: ₹ 15,921.516

Antigen

SMAD2

Classification

Recombinant Monoclonal

Concentration

0.5 mg/mL

Formulation

BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6

Gene Accession No.

Q15796

Gene Symbols

SMAD2

Immunogen

Between 225 And 275

Quantity

10 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

BLR130H

Conjugate

Unconjugated

Gene

SMAD2

Gene Alias

7120426M23Rik; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; Smad2; Smad-2; Smad2Deltaexon3

Host Species

Rabbit

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

4087

Content And Storage

2-8°C

Form

Liquid

Description

  • Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections
  • SMAD2 (MADH2, MAD2) regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation
  • SMAD2 interacts with the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation into the nucleus is a central event in TGF beta signaling
  • Phosphorylation of threonine 8 in the calmodulin-binding region of the MH1 domain by extracellular signal regulated kinase 1 (ERK1) enhances SMAD2 transcriptional activity, which is negatively regulated by calmodulin
  • In response to the TGF-beta signal, SMAD2 is phosphorylated by the TGF-beta receptors
  • The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4
  • The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors
  • SMAD2 can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin
  • Alternatively spliced transcript variants encoding the SMAD2 protein have been observed.

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Img

Thermo Scientific

PIMA544450

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Antigen:
SMAD2

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6

Gene Accession No.:
Q15796

Gene Symbols:
SMAD2

Immunogen:
Between 225 And 275

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
BLR130H

Conjugate:
Unconjugated

Gene:
SMAD2

Gene Alias:
7120426M23Rik; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; Smad2; Smad-2; Smad2Deltaexon3

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
4087

Content And Storage:
2-8°C

Form:
Liquid

Img

Thermo Scientific

PIMA544451

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Antigen:
CD47

Classification:
Recombinant Monoclonal

Concentration:
50 μg/mL

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 8.2

Gene Accession No.:
Q08722

Gene Symbols:
CD47

Immunogen:
Residues 19-142 (Ecd)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
BLR131H

Conjugate:
Unconjugated

Gene:
CD47

Gene Alias:
9130415E20Rik; AA407862; AI848868; antigen identified by monoclonal antibody 1D8; antigenic surface determinant protein OA3; AW108519; B430305P08Rik; Cd47; CD47 antigen; CD47 antigen (Rh-related antigen, integrin-associated signal transducer); CD47 antigen/integrin-associated protein; CD47 glycoprotein; CD47 molecule; CD47/IAP; IAP; integrin associated protein; integrin-associated protein; integrin-associated signal transducer; Itgp; Leukocyte surface antigen CD47; MER6; OA3; Protein MER6; Rh-related antigen; sCD47; soluble CD 47; soluble CD47

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
961

Content And Storage:
2-8°C

Form:
Liquid

Img

Thermo Scientific

PIMA544454

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Antigen:
SMAD4

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 6.8-7.4

Gene Accession No.:
Q13485

Gene Symbols:
SMAD4

Immunogen:
Between 1 And 50

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
BLR133J

Conjugate:
Unconjugated

Gene:
SMAD4

Gene Alias:
AW743858; D18Wsu70e; Deleted in Pancreatic Carcinoma 4 (DPC4); deleted in pancreatic carcinoma locus 4; deletion target in pancreatic carcinoma 4; Deletion target in pancreatic carcinoma 4 homolog; DPC4; hSMAD4; JIP; MAD (mothers against decapentaplegic Drosophila) homolog 4; MAD homolog 4; MAD homolog 4 (MADH4); Madh4; mothers against decapentaplegic homolog 4; Mothers against decapentaplegic homolog 4 (MADH4); mothers against decapentaplegic, Drosophila, homolog of, 4; mothers against DPP homolog 4; MYHRS; SMAD; SMAD 4; SMAD family member 4; SMAD, mothers against DPP homolog 4; SMAD4

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
4089

Content And Storage:
2-8°C

Form:
Liquid

Img

Thermo Scientific

PIMA544456

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Antigen:
FOXP1

Classification:
Recombinant Monoclonal

Concentration:
30 μg/mL

Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6

Gene Accession No.:
P58462, Q9H334

Gene Symbols:
FOXP1

Immunogen:
Between 627 And 677 (C-Term)

Quantity:
10 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
BLR134H

Conjugate:
Unconjugated

Gene:
FOXP1

Gene Alias:
12CC4; 3110052D19Rik; 4932443N09Rik; AI461938; AW494214; FLJ23741; Fork head related protein like B; fork head-related protein like B; forkhead box P1; forkhead box protein P1; Forkhead box protein P1 (FOXP1); Forkhead-related transcription factor 1; Foxp1; Glutamine rich factor 1; glutamine-rich factor 1; hFKH1B; HSPC215; mac-1-regulated forkhead; MFH; MGC12942; MGC88572; MGC99551; QRF1

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
108655, 27086

Content And Storage:
2-8°C

Form:
Liquid