PIMA544454
SMAD4 Recombinant Rabbit Monoclonal Antibody (BLR133J), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA544454-Each-of-1 | In Stock | ₹ 13,492.81 |
PIMA544454 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 13,492.81
GST (18%): ₹ 2,428.706
Total Price: ₹ 15,921.516
Antigen
SMAD4
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.09% sodium azide; pH 6.8-7.4
Gene Accession No.
Q13485
Gene Symbols
SMAD4
Immunogen
Between 1 And 50
Quantity
10 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
BLR133J
Conjugate
Unconjugated
Gene
SMAD4
Gene Alias
AW743858; D18Wsu70e; Deleted in Pancreatic Carcinoma 4 (DPC4); deleted in pancreatic carcinoma locus 4; deletion target in pancreatic carcinoma 4; Deletion target in pancreatic carcinoma 4 homolog; DPC4; hSMAD4; JIP; MAD (mothers against decapentaplegic Drosophila) homolog 4; MAD homolog 4; MAD homolog 4 (MADH4); Madh4; mothers against decapentaplegic homolog 4; Mothers against decapentaplegic homolog 4 (MADH4); mothers against decapentaplegic, Drosophila, homolog of, 4; mothers against DPP homolog 4; MYHRS; SMAD; SMAD 4; SMAD family member 4; SMAD, mothers against DPP homolog 4; SMAD4
Host Species
Rabbit
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
4089
Content And Storage
2-8°C
Form
Liquid
Description
- Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections
- Smad4 is encoded by the Smad4 gene that is located on chromosome 18 in humans
- Smad4 is also known as Smad family member 4, Sma- and Mad-related protein 4 or Mothers against decapentaplegic (MAD) homolog 4
- Smad4 contains N-terminal MH1 (MAD homology 1) and C-terminal MH2 (MAD homology 2) globular domains that are involved in DNA binding and protein interactions respectively
- Binding of the TGF-beta superfamily of ligands that includes Transforming Growth Factor -beta (TGF-beta) and bone morphogenetic protein (BMP) to its cognate receptor allows phosphorylation of Smad 1, 2, 3, 5 and 8 (R-Smad, Receptor Smad)
- This signals for heterotrimerization with Smad4 (co-Smad, co-mediator Smad) and translocation of the complex to the nucleus
- Inhibitory or antagonistic Smad (I-Smad) that includes Smad 6 and 7, interact with activated R-Smads and attenuate the signaling pathway
- Smad4 acts as a tumor suppressor protein by transcriptionally regulating its target genes such as Cyclin D1 (downregulation) and collagen (upregulation) that inhibit cell proliferation
- Dephosphorylation regulates nuclear export and nucleocytoplasmic dynamics of Smads.
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Antigen: SMAD4
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.09% sodium azide; pH 6.8-7.4
Gene Accession No.: Q13485
Gene Symbols: SMAD4
Immunogen: Between 1 And 50
Quantity: 10 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: BLR133J
Conjugate: Unconjugated
Gene: SMAD4
Gene Alias: AW743858; D18Wsu70e; Deleted in Pancreatic Carcinoma 4 (DPC4); deleted in pancreatic carcinoma locus 4; deletion target in pancreatic carcinoma 4; Deletion target in pancreatic carcinoma 4 homolog; DPC4; hSMAD4; JIP; MAD (mothers against decapentaplegic Drosophila) homolog 4; MAD homolog 4; MAD homolog 4 (MADH4); Madh4; mothers against decapentaplegic homolog 4; Mothers against decapentaplegic homolog 4 (MADH4); mothers against decapentaplegic, Drosophila, homolog of, 4; mothers against DPP homolog 4; MYHRS; SMAD; SMAD 4; SMAD family member 4; SMAD, mothers against DPP homolog 4; SMAD4
Host Species: Rabbit
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 4089
Content And Storage: 2-8°C
Form: Liquid
Antigen:
SMAD4
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.09% sodium azide; pH 6.8-7.4
Gene Accession No.:
Q13485
Gene Symbols:
SMAD4
Immunogen:
Between 1 And 50
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
BLR133J
Conjugate:
Unconjugated
Gene:
SMAD4
Gene Alias:
AW743858; D18Wsu70e; Deleted in Pancreatic Carcinoma 4 (DPC4); deleted in pancreatic carcinoma locus 4; deletion target in pancreatic carcinoma 4; Deletion target in pancreatic carcinoma 4 homolog; DPC4; hSMAD4; JIP; MAD (mothers against decapentaplegic Drosophila) homolog 4; MAD homolog 4; MAD homolog 4 (MADH4); Madh4; mothers against decapentaplegic homolog 4; Mothers against decapentaplegic homolog 4 (MADH4); mothers against decapentaplegic, Drosophila, homolog of, 4; mothers against DPP homolog 4; MYHRS; SMAD; SMAD 4; SMAD family member 4; SMAD, mothers against DPP homolog 4; SMAD4
Host Species:
Rabbit
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
4089
Content And Storage:
2-8°C
Form:
Liquid
Antigen: FOXP1
Classification: Recombinant Monoclonal
Concentration: 30 μg/mL
Formulation: BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.: P58462, Q9H334
Gene Symbols: FOXP1
Immunogen: Between 627 And 677 (C-Term)
Quantity: 10 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: BLR134H
Conjugate: Unconjugated
Gene: FOXP1
Gene Alias: 12CC4; 3110052D19Rik; 4932443N09Rik; AI461938; AW494214; FLJ23741; Fork head related protein like B; fork head-related protein like B; forkhead box P1; forkhead box protein P1; Forkhead box protein P1 (FOXP1); Forkhead-related transcription factor 1; Foxp1; Glutamine rich factor 1; glutamine-rich factor 1; hFKH1B; HSPC215; mac-1-regulated forkhead; MFH; MGC12942; MGC88572; MGC99551; QRF1
Host Species: Rabbit
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 108655, 27086
Content And Storage: 2-8°C
Form: Liquid
Antigen:
FOXP1
Classification:
Recombinant Monoclonal
Concentration:
30 μg/mL
Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.:
P58462, Q9H334
Gene Symbols:
FOXP1
Immunogen:
Between 627 And 677 (C-Term)
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
BLR134H
Conjugate:
Unconjugated
Gene:
FOXP1
Gene Alias:
12CC4; 3110052D19Rik; 4932443N09Rik; AI461938; AW494214; FLJ23741; Fork head related protein like B; fork head-related protein like B; forkhead box P1; forkhead box protein P1; Forkhead box protein P1 (FOXP1); Forkhead-related transcription factor 1; Foxp1; Glutamine rich factor 1; glutamine-rich factor 1; hFKH1B; HSPC215; mac-1-regulated forkhead; MFH; MGC12942; MGC88572; MGC99551; QRF1
Host Species:
Rabbit
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
108655, 27086
Content And Storage:
2-8°C
Form:
Liquid
Antigen: MACC1
Classification: Recombinant Monoclonal
Concentration: 0.25 mg/mL
Formulation: BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.: Q6ZN28
Gene Symbols: MACC1
Immunogen: Between 100 And 150
Quantity: 10 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: BLR135H
Conjugate: Unconjugated
Gene: MACC1
Gene Alias: 4732474O15Rik; 7A5; Gm267; MACC1; metastasis associated in colon cancer 1; metastasis-associated in colon cancer protein 1; putative binding protein 7a5; RGD1309838; SH3 domain-containing protein 7a5; SH3BP4L
Host Species: Rabbit
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 346389
Content And Storage: 2-8°C
Form: Liquid
Antigen:
MACC1
Classification:
Recombinant Monoclonal
Concentration:
0.25 mg/mL
Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.:
Q6ZN28
Gene Symbols:
MACC1
Immunogen:
Between 100 And 150
Quantity:
10 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
BLR135H
Conjugate:
Unconjugated
Gene:
MACC1
Gene Alias:
4732474O15Rik; 7A5; Gm267; MACC1; metastasis associated in colon cancer 1; metastasis-associated in colon cancer protein 1; putative binding protein 7a5; RGD1309838; SH3 domain-containing protein 7a5; SH3BP4L
Host Species:
Rabbit
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
346389
Content And Storage:
2-8°C
Form:
Liquid
Antigen: EphA2
Classification: Recombinant Monoclonal
Concentration: 40 μg/mL
Formulation: BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.: P29317
Gene Symbols: EPHA2
Immunogen: Residues 25-534 (Ecd)
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunoprecipitation, Western Blot
Clone: BLR136H
Conjugate: Unconjugated
Gene: EPHA2
Gene Alias: ARCC2; AW545284; CTPA; CTPP1; CTRCT6; Eck; EPH receptor A2; Epha2; ephrin receptor EphA2; Ephrin type-A receptor 2; Epithelial cell kinase; epithelial cell receptor protein tyrosine kinase; I79_019726; Myk2; Sek2; Sek-2; soluble EPHA2 variant 1; tyrosine-protein kinase receptor ECK; Tyrosine-protein kinase receptor MPK-5; tyrosine-protein kinase receptor SEK-2
Host Species: Rabbit
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 1969
Content And Storage: 2-8°C
Form: Liquid
Antigen:
EphA2
Classification:
Recombinant Monoclonal
Concentration:
40 μg/mL
Formulation:
BBS with 0.1% BSA and 0.09% sodium azide; pH 7.8-8.6
Gene Accession No.:
P29317
Gene Symbols:
EPHA2
Immunogen:
Residues 25-534 (Ecd)
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunoprecipitation, Western Blot
Clone:
BLR136H
Conjugate:
Unconjugated
Gene:
EPHA2
Gene Alias:
ARCC2; AW545284; CTPA; CTPP1; CTRCT6; Eck; EPH receptor A2; Epha2; ephrin receptor EphA2; Ephrin type-A receptor 2; Epithelial cell kinase; epithelial cell receptor protein tyrosine kinase; I79_019726; Myk2; Sek2; Sek-2; soluble EPHA2 variant 1; tyrosine-protein kinase receptor ECK; Tyrosine-protein kinase receptor MPK-5; tyrosine-protein kinase receptor SEK-2
Host Species:
Rabbit
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
1969
Content And Storage:
2-8°C
Form:
Liquid