PIMA544587

Cytokeratin 18 Recombinant Rabbit Monoclonal Antibody (RM279), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA544587-Each-of-1 In Stock ₹ 38,416.44

PIMA544587 - Each of 1

₹ 38,416.44

In Stock

Quantity

1

Base Price: ₹ 38,416.44

GST (18%): ₹ 6,914.959

Total Price: ₹ 45,331.399

Antigen

Cytokeratin 18

Classification

Recombinant Monoclonal

Concentration

200 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.

P05783

Gene Symbols

KRT18

Immunogen

A peptide corresponding to the N-terminus of human Cytokeratin-18.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

RM279

Conjugate

Unconjugated

Gene

KRT18

Gene Alias

cb83, Cell proliferation-inducing gene 46 protein, CK 18, CK18, CK-18, CYK18, cytokeratin 18, cytokeratin endo B, cytokeratin type -1, DAPK-1, Cytokeratin18, cytokeratin-18, dapk1, dorsal aorta proneprin kinesin-1, DreK18, Endo B, I79_023185, K 18, K18, keratin 18, keratin 18, type I, keratin 18a, tandem duplicate 1, keratin complex 1, acidic, gene 18, keratin D, Keratin, type I cytoskeletal 18, Keratin18, keratin-18, Kerd, KRT 18, Krt1-18, KRT18, krt18 {ECO:0000250, krt18a.1, LOC100008885, PIG46, sb:cb83, type I cytoskeletal 18, UniProtKB:P05783}, wu:fa13f02, wu:fb36b04

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

3875

Content And Storage

-20°C

Isotype

IgG

Description

  • This antibody reacts to human Aurora A/B/C only when phosphorylated at either Thr288, Thr232 or Thr198 respectively
  • There is no cross-reactivity to Aurora A/B/C that is not phosphorylated
  • Cytokeratin 18 (Keratin 18, KRT18, type I cytoskeletal 18) belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8
  • Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18
  • Further, cytokeratin 18 is found primarily in non-squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas, but not in squamous cell carcinomas
  • Hepatocellular carcinomas express only cytokeratins 8 and 18
  • Mutations in the cytokeratin 18 gene have been linked to cryptogenic cirrhosis
  • Two transcript variants encoding the same protein have been found for the cytokeratin 18 gene
  • Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies
  • The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA544587

--


Antigen:
Cytokeratin 18

Classification:
Recombinant Monoclonal

Concentration:
200 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
P05783

Gene Symbols:
KRT18

Immunogen:
A peptide corresponding to the N-terminus of human Cytokeratin-18.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM279

Conjugate:
Unconjugated

Gene:
KRT18

Gene Alias:
cb83, Cell proliferation-inducing gene 46 protein, CK 18, CK18, CK-18, CYK18, cytokeratin 18, cytokeratin endo B, cytokeratin type -1, DAPK-1, Cytokeratin18, cytokeratin-18, dapk1, dorsal aorta proneprin kinesin-1, DreK18, Endo B, I79_023185, K 18, K18, keratin 18, keratin 18, type I, keratin 18a, tandem duplicate 1, keratin complex 1, acidic, gene 18, keratin D, Keratin, type I cytoskeletal 18, Keratin18, keratin-18, Kerd, KRT 18, Krt1-18, KRT18, krt18 {ECO:0000250, krt18a.1, LOC100008885, PIG46, sb:cb83, type I cytoskeletal 18, UniProtKB:P05783}, wu:fa13f02, wu:fb36b04

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3875

Content And Storage:
-20°C

Isotype:
IgG

Img

Thermo Scientific

PIMA544588

--


Antigen:
SMAD4

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
O70437, P97471, Q13485

Gene Symbols:
SMAD4

Immunogen:
A peptide corresponding to the C-terminus of human Smad4.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM277

Conjugate:
Unconjugated

Gene:
SMAD4

Gene Alias:
AW743858, D18Wsu70e, Deleted in Pancreatic Carcinoma 4 (DPC4), deleted in pancreatic carcinoma locus 4, deletion target in pancreatic carcinoma 4, Deletion target in pancreatic carcinoma 4 homolog, DPC4, hSMAD4, JIP, MAD (mothers against decapentaplegic Drosophila) homolog 4, MAD homolog 4, MAD homolog 4 (MADH4), Madh4, mothers against decapentaplegic homolog 4, Mothers against decapentaplegic homolog 4 (MADH4), mothers against decapentaplegic, Drosophila, homolog of, 4, mothers against DPP homolog 4, MYHRS, SMAD, SMAD 4, SMAD family member 4, SMAD, mothers against DPP homolog 4, SMAD4

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
17128, 4089, 50554

Content And Storage:
-20°C

Isotype:
IgG

Img

Thermo Scientific

PIMA544589

--


Antigen:
Nkx3.1

Classification:
Recombinant Monoclonal

Concentration:
400 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
Q99801

Gene Symbols:
NKX3-1

Immunogen:
A peptide corresponding to the N-terminus of human Nkx3.1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Clone:
RM430

Conjugate:
Unconjugated

Gene:
NKX3-1

Gene Alias:
bagpipe, BAPX2, Bax, Drosophila NK-3 transcription factor, locus 1, homeobox protein NK-3 homolog A, Homeobox protein Nkx-3.1, NK homeobox, family 3, A, NK3 homeobox 1, NK3 transcription factor homolog A, NK3 transcription factor related, locus 1, NK-3 transcription factor, locus 1, NK-3 transcription factor, locus 1 (Drosophila), NKX3, NKX3.1, Nkx-3.1, Nkx3-1, NKX3-1 antibody, NKX3A, prostate-specific ag

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4824

Content And Storage:
-20°C

Isotype:
IgG

Img

Thermo Scientific

PIMA544590

--


Antigen:
Synaptophysin

Classification:
Recombinant Monoclonal

Concentration:
40 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
P08247

Gene Symbols:
Syp

Immunogen:
A peptide corresponding to the C-terminus of Synaptophysin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM258

Conjugate:
Unconjugated

Gene:
Syp

Gene Alias:
A230093K24Rik, AI848995, BM89 antigen, I79_012252, Major synaptic vesicle protein p38, MRX96, MRXSYP, p38, Syn, Synaptophysin, Syp, Syp I, Syp1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6855

Content And Storage:
-20°C

Isotype:
IgG